CA2789945A1 - Universal virus-like particle (vlp) influenza vaccines - Google Patents
Universal virus-like particle (vlp) influenza vaccines Download PDFInfo
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- CA2789945A1 CA2789945A1 CA2789945A CA2789945A CA2789945A1 CA 2789945 A1 CA2789945 A1 CA 2789945A1 CA 2789945 A CA2789945 A CA 2789945A CA 2789945 A CA2789945 A CA 2789945A CA 2789945 A1 CA2789945 A1 CA 2789945A1
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- A61K2039/5258—Virus-like particles
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16023—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
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- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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Landscapes
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| WO2009076778A1 (en) | 2007-11-27 | 2009-06-25 | Medicago Inc. | Recombinant influenza virus-like particles (vlps) produced in transgenic plants expressing hemagglutinin |
| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| EP2536428B1 (en) * | 2010-02-18 | 2018-12-05 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| CN103154021A (zh) * | 2010-08-16 | 2013-06-12 | 威斯特解剖及生物研究所 | 通用甲型流感疫苗 |
| CN103957891B (zh) | 2011-09-23 | 2017-01-11 | 美利坚合众国由健康及人类服务部部长代表 | 基于流感血凝素蛋白的新颖疫苗 |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| DK2760882T5 (da) | 2011-09-30 | 2024-06-24 | Medicago Inc | Forøgelse af udbyttet af viruslignende partikler i planter |
| WO2013059403A1 (en) * | 2011-10-19 | 2013-04-25 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of influenza virus infection |
| IN2014DN07152A (enExample) | 2012-03-22 | 2015-04-24 | Fraunhofer Usa Inc | |
| EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
| US10358652B2 (en) | 2013-03-28 | 2019-07-23 | Medicago Inc. | Influenza virus-like particle production in plants |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| EP3733244A1 (en) * | 2013-10-02 | 2020-11-04 | Medlmmune, LLC | Neutralizing anti-influenza a antibodies and uses thereof |
| WO2015054639A1 (en) | 2013-10-11 | 2015-04-16 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Epstein-barr virus vaccines |
| EP3089755A1 (en) | 2014-01-03 | 2016-11-09 | Fundacion Biofisica Bizkaia | VLPs, METHODS FOR THEIR OBTENTION AND APPLICATIONS THEREOF |
| WO2015195218A1 (en) * | 2014-06-20 | 2015-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Polyvalent influenza virus-like particles (vlps) and use as vaccines |
| BR112017014219A2 (pt) | 2014-12-31 | 2018-03-06 | The Usa As Represented By The Secretary Dept Of Health And Human Services | vacinas à base de nanopartículas multivalentes |
| US11324816B2 (en) | 2015-08-31 | 2022-05-10 | Technovax, Inc. | Human respiratory syncytial virus (HRSV) virus-like particles (VLPS) based vaccine |
| IL303650B2 (en) | 2016-09-02 | 2025-02-01 | Us Health | Stable group 2 trimers from the stem region of influenza hemagglutinin and their uses |
| MX2023012554A (es) | 2018-12-12 | 2023-11-08 | Cambridge Tech Llc | Vacuna universal contra la gripe. |
| CN110272473B (zh) * | 2019-07-10 | 2021-03-02 | 军事科学院军事医学研究院军事兽医研究所 | 甲型流感通用型病毒样颗粒及其制备方法和应用 |
| US20230321219A1 (en) * | 2020-08-17 | 2023-10-12 | Technovax, Inc. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS [SARS-CoV-2]-VIRUS-LIKE PARTICLE [VLP] VACCINE: COMPOSITIONS, DELIVERY STRATEGIES, METHODS AND USES |
| AU2021342576A1 (en) * | 2020-09-21 | 2023-04-06 | University Of Georgia Research Foundation, Inc. | PIV5-based covid-19 vaccine |
| CN112342149A (zh) * | 2020-11-12 | 2021-02-09 | 新疆畜牧科学院兽医研究所（新疆畜牧科学院动物临床医学研究中心） | 一种禽流感病毒样颗粒组装表达系统及其应用 |
| AU2022425707A1 (en) * | 2021-12-31 | 2024-07-04 | Mynvax Private Limited | Polypeptide fragments, immunogenic composition against influenza virus, and implementations thereof |
| CN120053630B (zh) * | 2025-04-28 | 2025-07-18 | 中国医学科学院医学生物学研究所 | 一种广谱流感疫苗的抗原表位肽组合及其应用 |
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| AU2001268662A1 (en) * | 2000-06-23 | 2002-01-08 | Wyeth Holdings Corporation | Assembly of wild-type and chimeric influenza virus-like particles (VLPs) |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| US8080255B2 (en) | 2003-07-11 | 2011-12-20 | Novavax Inc. | Functional influenza virus like particles (VLPs) |
| US20060051859A1 (en) * | 2004-09-09 | 2006-03-09 | Yan Fu | Long acting human interferon analogs |
| MX2008000890A (es) * | 2005-07-19 | 2008-03-18 | Dow Global Technologies Inc | Vacunas de influenza (flu) recombinantes. |
| AU2006304640B2 (en) * | 2005-10-18 | 2012-10-11 | Novavax, Inc. | Functional influenza virus like particles (VLPs) |
| US9101578B2 (en) | 2006-05-01 | 2015-08-11 | Technovax, Inc. | Polyvalent influenza virus-like particle (VLP) compositions |
| WO2007130327A2 (en) | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Influenza virus-like particle (vlp) compositions |
| WO2008094200A2 (en) * | 2006-07-27 | 2008-08-07 | Ligocyte Pharmaceuticals, Inc | Chimeric virus-like particles |
| EP2089515A4 (en) | 2006-11-16 | 2011-02-23 | Novavax Inc | VIRUSUAL PARTICLES OF RESPIRATORY SYNZYTIAL VIRUS |
| CN102223895B (zh) * | 2008-11-25 | 2014-11-05 | 巴克斯特保健股份有限公司 | 生产pH稳定的包膜病毒的方法 |
| US9051359B2 (en) * | 2009-03-30 | 2015-06-09 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
| EP2536428B1 (en) * | 2010-02-18 | 2018-12-05 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| KR102072582B1 (ko) * | 2012-12-31 | 2020-02-03 | 엘지전자 주식회사 | 듀얼 디스플레이 방법 및 장치 |
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| EP2536428A1 (en) | 2012-12-26 |
| US9352031B2 (en) | 2016-05-31 |
| EP2536428B1 (en) | 2018-12-05 |
| EP2536428A4 (en) | 2014-04-09 |
| US20110212128A1 (en) | 2011-09-01 |
| JP6524555B2 (ja) | 2019-06-05 |
| JP2013520167A (ja) | 2013-06-06 |
| US20200297836A1 (en) | 2020-09-24 |
| JP2016198107A (ja) | 2016-12-01 |
| US10080796B2 (en) | 2018-09-25 |
| US11529410B2 (en) | 2022-12-20 |
| US10695418B2 (en) | 2020-06-30 |
| CN102858368A (zh) | 2013-01-02 |
| US20190091323A1 (en) | 2019-03-28 |
| US20160303223A1 (en) | 2016-10-20 |
| CN102858368B (zh) | 2017-04-12 |
| WO2011102900A1 (en) | 2011-08-25 |
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