CA2789945A1 - Universal virus-like particle (vlp) influenza vaccines - Google Patents
Universal virus-like particle (vlp) influenza vaccines Download PDFInfo
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- CA2789945A1 CA2789945A1 CA2789945A CA2789945A CA2789945A1 CA 2789945 A1 CA2789945 A1 CA 2789945A1 CA 2789945 A CA2789945 A CA 2789945A CA 2789945 A CA2789945 A CA 2789945A CA 2789945 A1 CA2789945 A1 CA 2789945A1
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
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- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16023—Virus like particles [VLP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
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-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| CA2615372A1 (en) | 2007-07-13 | 2009-01-13 | Marc-Andre D'aoust | Influenza virus-like particles (vlps) comprising hemagglutinin |
| PT2610345E (pt) | 2007-11-27 | 2016-01-11 | Medicago Inc | Partículas semelhantes ao vírus (vlps) da gripe recombinantes produzidas em plantas transgénicas que expressam hemaglutinina |
| WO2011102900A1 (en) | 2010-02-18 | 2011-08-25 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| WO2012024283A2 (en) * | 2010-08-16 | 2012-02-23 | The Wistar Institute Of Anatomy And Biology | Universal influenza a vaccines |
| US9441019B2 (en) | 2011-09-23 | 2016-09-13 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Influenza hemagglutinin protein-based vaccines |
| US11390878B2 (en) | 2011-09-30 | 2022-07-19 | Medicago Inc. | Increasing protein yield in plants |
| CN116218900A (zh) * | 2011-09-30 | 2023-06-06 | 麦迪卡格公司 | 增加植物中病毒样颗粒的产率 |
| WO2013059403A1 (en) * | 2011-10-19 | 2013-04-25 | Immunotope, Inc. | Cytotoxic t-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of influenza virus infection |
| BR112014019755B1 (pt) | 2012-03-22 | 2022-02-22 | Fraunhofer Usa, Inc | Partícula do tipo viral; método de produção das partículas do tipo viral; composição imunogênica e uso das partículas do tipo viral |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| US12467058B2 (en) | 2013-03-28 | 2025-11-11 | Aramis Biotechnologies Inc. | Influenza virus-like particle production in plants |
| EP2978848B1 (en) | 2013-03-28 | 2020-05-06 | Medicago Inc. | Influenza virus-like particle production in plants |
| JP6535675B2 (ja) * | 2013-10-02 | 2019-06-26 | メディミューン，エルエルシー | 抗ａ型インフルエンザ抗体の中和及びその使用 |
| CN105792842B (zh) | 2013-10-11 | 2020-06-02 | 美利坚合众国, 由健康及人类服务部部长代表 | 埃巴病毒疫苗 |
| WO2015101666A1 (en) | 2014-01-03 | 2015-07-09 | Fundación Biofísica Bizkaia | VLPs, METHODS FOR THEIR OBTENTION AND APPLICATIONS THEREOF |
| US10130700B2 (en) | 2014-06-20 | 2018-11-20 | The United States of America, as represented by the Secretary, DHHS | Polyvalent influenza virus-like particles (VLPS) and use as vaccines |
| AU2015373928B2 (en) | 2014-12-31 | 2019-10-17 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Novel multivalent nanoparticle-based vaccines |
| EP3344290A4 (en) * | 2015-08-31 | 2019-02-27 | Technovax, Inc. | VACCINE BASED ON VIRUS-LIKE PARTICLES OF HUMAN RESPIRATORY SYNZYTIAL VIRUS (HRSV) |
| JP7183149B2 (ja) | 2016-09-02 | 2022-12-05 | ザ・ユナイテッド・ステイツ・オブ・アメリカ・アズ・リプリゼンテッド・バイ・ザ・セクレタリー・デパートメント・オブ・ヘルス・アンド・ヒューマン・サービシーズ | 安定化されたグループ２インフルエンザヘマグルチニンステム領域三量体およびその使用 |
| MX2019014943A (es) | 2018-12-12 | 2020-08-06 | Cambridge Tech Llc | Vacuna universal contra la gripe. |
| CN110272473B (zh) * | 2019-07-10 | 2021-03-02 | 军事科学院军事医学研究院军事兽医研究所 | 甲型流感通用型病毒样颗粒及其制备方法和应用 |
| EP4196160A2 (en) * | 2020-08-17 | 2023-06-21 | Technovax, Inc. | [sars-cov-2]-virus-like particle [vlp] vaccine: compositions, delivery strategies, methods and uses |
| CA3196157A1 (en) * | 2020-09-21 | 2022-03-24 | University Of Georgia Research Foundation, Inc. | Piv5-based covid-19 vaccine |
| CN112342149A (zh) * | 2020-11-12 | 2021-02-09 | 新疆畜牧科学院兽医研究所（新疆畜牧科学院动物临床医学研究中心） | 一种禽流感病毒样颗粒组装表达系统及其应用 |
| WO2023126982A1 (en) * | 2021-12-31 | 2023-07-06 | Mynvax Private Limited | Polypeptide fragments, immunogenic composition against influenza virus, and implementations thereof |
| CN120053630B (zh) * | 2025-04-28 | 2025-07-18 | 中国医学科学院医学生物学研究所 | 一种广谱流感疫苗的抗原表位肽组合及其应用 |
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| BRPI0111830B8 (pt) * | 2000-06-23 | 2021-05-25 | American Cyanamid Co | método de produção de partículas semelhantes ao vírus da influenza (vlps), vlps da influenza, vlps quiméricas, composições imunogênica e farmacêutica, e, usos de vlps da influenza e de vlps quiméricas |
| US8592197B2 (en) * | 2003-07-11 | 2013-11-26 | Novavax, Inc. | Functional influenza virus-like particles (VLPs) |
| US8080255B2 (en) | 2003-07-11 | 2011-12-20 | Novavax Inc. | Functional influenza virus like particles (VLPs) |
| US20060051859A1 (en) * | 2004-09-09 | 2006-03-09 | Yan Fu | Long acting human interferon analogs |
| BRPI0613625A2 (pt) * | 2005-07-19 | 2011-01-18 | Dow Global Technologies Inc | vacinas da gripe recombinantes |
| TWI488968B (zh) * | 2005-10-18 | 2015-06-21 | Novavax Inc | 功能性流行性感冒類病毒顆粒（ＶＬＰｓ） |
| WO2007130330A2 (en) * | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Polyvalent influenza virus-like particle (vlp) compositions |
| WO2007130327A2 (en) * | 2006-05-01 | 2007-11-15 | Technovax, Inc. | Influenza virus-like particle (vlp) compositions |
| EP2044224A4 (en) * | 2006-07-27 | 2011-04-13 | Ligocyte Pharmaceuticals Inc | CHIMERIC VIRUS TYPE PARTICLES |
| EP2089515A4 (en) * | 2006-11-16 | 2011-02-23 | Novavax Inc | VIRUSUAL PARTICLES OF RESPIRATORY SYNZYTIAL VIRUS |
| US8883479B2 (en) * | 2008-11-25 | 2014-11-11 | Baxter Healthcare Sa | Method for production of pH stable enveloped viruses |
| CA2787099A1 (en) * | 2009-03-30 | 2010-10-14 | Anice C. Lowen | Influenza virus hemagglutinin polypeptides containing stem domains, vaccines and uses thereof |
| WO2011102900A1 (en) * | 2010-02-18 | 2011-08-25 | Technovax, Inc. | Universal virus-like particle (vlp) influenza vaccines |
| KR102072582B1 (ko) * | 2012-12-31 | 2020-02-03 | 엘지전자 주식회사 | 듀얼 디스플레이 방법 및 장치 |
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| US10695418B2 (en) | 2020-06-30 |
| EP2536428A1 (en) | 2012-12-26 |
| JP6524555B2 (ja) | 2019-06-05 |
| US10080796B2 (en) | 2018-09-25 |
| US20190091323A1 (en) | 2019-03-28 |
| EP2536428B1 (en) | 2018-12-05 |
| CN102858368A (zh) | 2013-01-02 |
| US20110212128A1 (en) | 2011-09-01 |
| US20200297836A1 (en) | 2020-09-24 |
| CN102858368B (zh) | 2017-04-12 |
| WO2011102900A1 (en) | 2011-08-25 |
| US9352031B2 (en) | 2016-05-31 |
| JP2013520167A (ja) | 2013-06-06 |
| US11529410B2 (en) | 2022-12-20 |
| JP2016198107A (ja) | 2016-12-01 |
| EP2536428A4 (en) | 2014-04-09 |
| US20160303223A1 (en) | 2016-10-20 |
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