CA2785168C - Swallowable drug delivery device and methods of drug delivery - Google Patents

Swallowable drug delivery device and methods of drug delivery Download PDF

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Publication number
CA2785168C
CA2785168C CA2785168A CA2785168A CA2785168C CA 2785168 C CA2785168 C CA 2785168C CA 2785168 A CA2785168 A CA 2785168A CA 2785168 A CA2785168 A CA 2785168A CA 2785168 C CA2785168 C CA 2785168C
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CA
Canada
Prior art keywords
tissue penetrating
capsule
penetrating member
therapeutic agent
drug
Prior art date
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Active
Application number
CA2785168A
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English (en)
French (fr)
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CA2785168A1 (en
Inventor
Mir Imran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rani Therapeutics LLC
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Rani Therapeutics LLC
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44196421&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2785168(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Rani Therapeutics LLC filed Critical Rani Therapeutics LLC
Publication of CA2785168A1 publication Critical patent/CA2785168A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/065—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/07—Endoradiosondes
    • A61B5/073—Intestinal transmitters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14539—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring pH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4094—Diagnosing or monitoring seizure diseases, e.g. epilepsy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • A61M2005/14284—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Optics & Photonics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Human Computer Interaction (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2785168A 2009-12-24 2010-12-23 Swallowable drug delivery device and methods of drug delivery Active CA2785168C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US28476609P 2009-12-24 2009-12-24
US61/284,766 2009-12-24
US34033110P 2010-03-15 2010-03-15
US61/340,331 2010-03-15
US39530410P 2010-05-10 2010-05-10
US61/395,304 2010-05-10
PCT/US2010/062070 WO2011079302A2 (en) 2009-12-24 2010-12-23 Swallowable drug delivery device and methods of drug delivery

Publications (2)

Publication Number Publication Date
CA2785168A1 CA2785168A1 (en) 2011-06-30
CA2785168C true CA2785168C (en) 2018-04-17

Family

ID=44196421

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2785168A Active CA2785168C (en) 2009-12-24 2010-12-23 Swallowable drug delivery device and methods of drug delivery

Country Status (11)

Country Link
EP (4) EP4056173B1 (https=)
JP (7) JP2013515576A (https=)
CN (2) CN102905753B (https=)
AU (5) AU2010336330B2 (https=)
CA (1) CA2785168C (https=)
DK (3) DK3756657T3 (https=)
ES (2) ES3031275T3 (https=)
FI (1) FI3756657T3 (https=)
PL (2) PL3756657T3 (https=)
PT (1) PT3756657T (https=)
WO (1) WO2011079302A2 (https=)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8682440B2 (en) 2009-08-03 2014-03-25 Incube Labs, Llc Swallowable capsule and method for stimulating incretin production within the intestinal tract
CA2785168C (en) 2009-12-24 2018-04-17 Incube Labs, Llc Swallowable drug delivery device and methods of drug delivery
US8721620B2 (en) 2009-12-24 2014-05-13 Rani Therapeutics, Llc Swallowable drug delivery device and methods of drug delivery
CA2792862C (en) * 2010-03-10 2018-03-06 Incube Labs, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809271B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising liraglutide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8846040B2 (en) 2010-12-23 2014-09-30 Rani Therapeutics, Llc Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9861683B2 (en) 2010-12-23 2018-01-09 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9259386B2 (en) 2010-12-23 2016-02-16 Rani Therapeutics, Llc Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8764733B2 (en) 2010-12-23 2014-07-01 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9629799B2 (en) 2010-12-23 2017-04-25 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9402806B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8809269B2 (en) 2010-12-23 2014-08-19 Rani Therapeutics, Llc Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9149617B2 (en) 2010-12-23 2015-10-06 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9284367B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9402807B2 (en) 2010-12-23 2016-08-02 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US9283179B2 (en) 2010-12-23 2016-03-15 Rani Therapeutics, Llc GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8980822B2 (en) 2010-12-23 2015-03-17 Rani Therapeutics, Llc Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10639272B2 (en) 2010-12-23 2020-05-05 Rani Therapeutics, Llc Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device
US8734429B2 (en) 2010-12-23 2014-05-27 Rani Therapeutics, Llc Device, system and methods for the oral delivery of therapeutic compounds
US9415004B2 (en) 2010-12-23 2016-08-16 Rani Therapeutics, Llc Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US8969293B2 (en) 2010-12-23 2015-03-03 Rani Therapeutics, Llc Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
PT2665512T (pt) 2011-01-21 2016-08-29 Obalon Therapeutics Inc Dispositivo intragástrico
PT3653223T (pt) 2011-06-29 2021-12-06 Rani Therapeutics Llc Dispositivo para a entrega oral de compostos terapêuticos
ES2773115T3 (es) * 2011-06-29 2020-07-09 Rani Therapeutics Llc Preparados de agentes terapéuticos para la administración hacia el interior de una luz del tubo intestinal utilizando un dispositivo tragable para la administración de fármacos
EP2968071B1 (en) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Device for oral delivery of therapeutic compounds
US20150064241A1 (en) * 2013-09-05 2015-03-05 Google Inc. Delivery of Functionalized Particles
CN103479401B (zh) * 2013-09-29 2015-08-19 中山大学附属第一医院 一种肠道生物标志物采样器
EP3142645A4 (en) 2014-05-15 2017-12-27 Rani Therapeutics, LLC Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins
US10689460B2 (en) 2014-05-15 2020-06-23 Incube Labs, Llc PCSK9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US11548940B2 (en) 2014-05-15 2023-01-10 Rani Therapeutics, Llc Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
WO2015191922A1 (en) * 2014-06-11 2015-12-17 Massachusetts Institute Of Technology Enteric elastomers
WO2016155671A1 (zh) * 2015-04-02 2016-10-06 傅君志 可吞咽式装置
AU2016261599B2 (en) * 2015-05-08 2021-08-26 Rani Therapeutics, Llc Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
WO2017044665A1 (en) * 2015-09-08 2017-03-16 Mir Imran Pcsk9 antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US10220003B2 (en) * 2016-03-09 2019-03-05 Incube Labs, Llc Methods and articles for delivering viable cells into solid tissue
KR20230042759A (ko) 2016-09-09 2023-03-29 비오라 쎄라퓨틱스, 인크. 분배가능한 물질의 전달을 위한 전자기계식 섭취가능한 디바이스
FR3059553B1 (fr) * 2016-12-07 2021-04-23 Univ Grenoble Alpes Dispositif implantable
EP3554346B1 (en) 2016-12-14 2024-01-31 Biora Therapeutics, Inc. Treatment of a disease of the gastrointestinal tract with an immunosuppressant
CN107050578A (zh) * 2017-05-04 2017-08-18 梁曦 一种药物自动注射装置
WO2018213579A1 (en) * 2017-05-17 2018-11-22 Massachusetts Institute Of Technology Self-actuating articles
IL270674B2 (en) * 2017-05-19 2024-12-01 Shalon Tidhar Instruments and methods for collecting samples from the digestive system
US11103187B2 (en) * 2017-06-12 2021-08-31 Rani Therapeutics, Llc Swallowable capsule, system and method for measuring gastric emptying parameters
CN108324231A (zh) * 2018-03-14 2018-07-27 潍坊学院 一种自清洁上药胶囊内镜
SG11202009767PA (en) 2018-04-10 2020-10-29 Panacea Biomatx Inc Method and system for making personalized nutritional and pharmaceutical formulations using additive manufacturing
US10675248B2 (en) * 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
US20210196627A1 (en) * 2018-08-15 2021-07-01 Lyndra, Inc. Systems for enteric delivery of therapeutic agents
WO2020041774A1 (en) * 2018-08-23 2020-02-27 Baywind Bioventures Capsule device for delivery of active agent to gastrointestinal tract
US12128133B2 (en) * 2018-09-25 2024-10-29 Rani Therapeutics, Llc Ingestible device with expandable enclosure
US20220249814A1 (en) 2018-11-19 2022-08-11 Progenity, Inc. Methods and devices for treating a disease with biotherapeutics
EP4696361A3 (en) 2019-02-01 2026-04-15 Massachusetts Institute of Technology Systems and methods for liquid injection
JP7420819B2 (ja) 2019-02-01 2024-01-23 ノボ・ノルデイスク・エー／エス 作動機構を有する医療デバイス
US11833319B2 (en) * 2019-03-01 2023-12-05 Rani Therapeutics, Llc Propulsive drug delivery from a swallowable device into a patients intestinal tract
CN113966242A (zh) * 2019-06-07 2022-01-21 诺和诺德股份有限公司 具有递送构件脱离的可摄取装置
US11793980B2 (en) * 2019-08-31 2023-10-24 Celero Systems, Inc. Intestinal attachment device
WO2021071927A1 (en) * 2019-10-08 2021-04-15 Incube Labs, Llc Controlled release formulation delivery device
CN121197633A (zh) 2019-12-13 2025-12-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
WO2021146296A1 (en) * 2020-01-14 2021-07-22 Rani Therapeutics, Llc Swallowable devices for drug delivery in an intestinal tract
WO2021167993A1 (en) * 2020-02-18 2021-08-26 Rani Therapeutics, Llc Injection of a therapeutic formulation into a wall of the gastrointestinal tract
WO2021198353A1 (en) * 2020-03-31 2021-10-07 Danmarks Tekniske Universitet A flexible foil for the delivery of therapeutic cargos
WO2022000078A1 (en) * 2020-06-29 2022-01-06 The Governing Council Of The University Of Toronto Magnetically actuated capsule
CN111772589B (zh) * 2020-08-04 2022-07-12 重庆金山医疗技术研究院有限公司 一种判断胶囊内镜是否适用的检测系统及其探路胶囊
JP7654068B2 (ja) * 2020-09-16 2025-03-31 イーライ リリー アンド カンパニー 拡張アームを有する経口薬物送達デバイス
US20240358629A1 (en) * 2021-07-19 2024-10-31 Cochlear Limited Self-propelled pharmaceutical delivery capsules
CN113598690B (zh) * 2021-08-10 2023-07-28 安徽光阵光电科技有限公司 一种用于人体体内医疗的内窥镜药丸
CA3252806A1 (en) * 2022-02-21 2023-08-24 Rani Therapeutics, Llc DEVICES, ASSEMBLIES AND METHODS FOR ADMINISTRATING A FLUID PREPARATION INTO A DIGESTIVE TRACT
CN119424884B (zh) * 2024-09-29 2025-10-10 北京水木金昇医疗科技服务有限公司 一种递送注射药物的微针胶囊及其应用

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474785A (en) * 1990-01-24 1995-12-12 Alza Corporation Delivery system comprising means for controlling internal pressure
US5217449A (en) * 1990-12-11 1993-06-08 Miyarisan Kabushiki Kaisha Medical capsule and apparatus for activating the same
DK42093D0 (da) 1993-04-07 1993-04-07 Bukh Meditec Administrationsmetode
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
AU6517900A (en) 1999-08-03 2001-02-19 Smith & Nephew, Inc. Controlled release implantable devices
US6478776B1 (en) 2000-04-05 2002-11-12 Biocardia, Inc. Implant delivery catheter system and methods for its use
GB0017999D0 (en) * 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
JP4643089B2 (ja) * 2001-09-27 2011-03-02 オリンパス株式会社 カプセル型医療装置
JP2002186672A (ja) * 2001-09-28 2002-07-02 Olympus Optical Co Ltd 医療用カプセル装置
FR2835730B1 (fr) * 2002-02-11 2004-12-10 C T M Ct De Transfert Des Micr Dispositif pour la delivrance de substances et le prelevement intracorporel
AU2003243750A1 (en) * 2002-06-25 2004-01-06 Sung-Yun Kwon Rapidly dissolving micro-perforator for drug delivery and other applications
US7118531B2 (en) * 2002-09-24 2006-10-10 The Johns Hopkins University Ingestible medical payload carrying capsule with wireless communication
AU2003288516A1 (en) * 2002-12-26 2004-07-22 Given Imaging Ltd. Immobilizable in vivo sensing device
AU2004208580A1 (en) 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
JP2005021677A (ja) * 2003-06-10 2005-01-27 Medorekkusu:Kk 経皮投薬用パッドベース、及び注射針
US8000784B2 (en) * 2004-04-19 2011-08-16 The Invention Science Fund I, Llc Lumen-traveling device
DE102004026615A1 (de) * 2004-06-01 2005-12-29 Siemens Ag Vorrichtung und Verfahren zur Freisetzung eines in das Körperinnere eines Patienten geführten therapeutischen Mittels
US20060153894A1 (en) * 2004-06-30 2006-07-13 Ragae Ghabrial Multi-compartment delivery system
DE112005002806A5 (de) * 2004-09-13 2007-08-30 Luk Lamellen Und Kupplungsbau Beteiligungs Kg Verfahren zur Lagebestimmung bei einem EC-Motor
CA2582929A1 (en) * 2004-09-30 2006-04-06 Duocure, Inc. Device and method for treating weight disorders
JP2008532568A (ja) * 2005-01-18 2008-08-21 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 電子制御されるカプセル
WO2006126653A1 (ja) * 2005-05-27 2006-11-30 Olympus Corporation 被検体内導入装置
US20070078414A1 (en) 2005-08-05 2007-04-05 Mcallister Devin V Methods and devices for delivering agents across biological barriers
JP4402648B2 (ja) * 2005-12-16 2010-01-20 オリンパス株式会社 被検体内導入装置
AU2006334020B2 (en) 2005-12-30 2012-07-05 Mor Research Applications Ltd. Device and method for treating the anal sphincter
GB0603252D0 (en) * 2006-02-17 2006-03-29 Axcess Ltd Dissolution aids for oral peptide delivery
US7741273B2 (en) 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
DE102006047537B4 (de) * 2006-10-07 2024-05-16 Sanofi-Aventis Deutschland Gmbh Verfahren und Vorrichtung zur Bestimmung der Position eines Stopfens einer Ampulle für ein Arzneimittel in einem medizinischen Gerät sowie deren Verwendung, ein entsprechendes medizinisches Gerät sowie Herstellung eines medizinischen Geräts
US20080214919A1 (en) * 2006-12-26 2008-09-04 Lifescan, Inc. System and method for implementation of glycemic control protocols
WO2009041525A1 (ja) * 2007-09-26 2009-04-02 Olympus Medical Systems Corp. 被検体内導入システム
CA2785168C (en) 2009-12-24 2018-04-17 Incube Labs, Llc Swallowable drug delivery device and methods of drug delivery

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