CA2784450C - Polypeptides of pseudomonas aeruginosa - Google Patents
Polypeptides of pseudomonas aeruginosa Download PDFInfo
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- CA2784450C CA2784450C CA2784450A CA2784450A CA2784450C CA 2784450 C CA2784450 C CA 2784450C CA 2784450 A CA2784450 A CA 2784450A CA 2784450 A CA2784450 A CA 2784450A CA 2784450 C CA2784450 C CA 2784450C
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- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 229960001153 serine Drugs 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- RYMZZMVNJRMUDD-HGQWONQESA-N simvastatin Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@H](C)C[C@@H]([C@H]12)OC(=O)C(C)(C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 RYMZZMVNJRMUDD-HGQWONQESA-N 0.000 description 1
- 238000001542 size-exclusion chromatography Methods 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- QBSSGICBQYAHPS-OUPRKWGVSA-M sodium;(2s)-2-azaniumyl-3-[[(2r)-2,3-di(dodecanoyloxy)propoxy]-oxidophosphoryl]oxypropanoate Chemical compound [Na+].CCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OC[C@H]([NH3+])C([O-])=O)OC(=O)CCCCCCCCCCC QBSSGICBQYAHPS-OUPRKWGVSA-M 0.000 description 1
- FGGPAWQCCGEWTJ-UHFFFAOYSA-M sodium;2,3-bis(sulfanyl)propane-1-sulfonate Chemical compound [Na+].[O-]S(=O)(=O)CC(S)CS FGGPAWQCCGEWTJ-UHFFFAOYSA-M 0.000 description 1
- ALPWRKFXEOAUDR-GKEJWYBXSA-M sodium;[(2r)-2,3-di(octadecanoyloxy)propyl] hydrogen phosphate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)([O-])=O)OC(=O)CCCCCCCCCCCCCCCCC ALPWRKFXEOAUDR-GKEJWYBXSA-M 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 208000011117 substance-related disease Diseases 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- ZZIZZTHXZRDOFM-XFULWGLBSA-N tamsulosin hydrochloride Chemical compound [H+].[Cl-].CCOC1=CC=CC=C1OCCN[C@H](C)CC1=CC=C(OC)C(S(N)(=O)=O)=C1 ZZIZZTHXZRDOFM-XFULWGLBSA-N 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 229940118376 tetanus toxin Drugs 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 125000004149 thio group Chemical group *S* 0.000 description 1
- 125000003396 thiol group Chemical group [H]S* 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000005199 ultracentrifugation Methods 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33122101P | 2001-11-13 | 2001-11-13 | |
| US60/331,221 | 2001-11-13 | ||
| CA2466474A CA2466474C (en) | 2001-11-13 | 2002-11-13 | Compositions comprising spa-1, spa-2 and spa-3, polypeptides and related uses |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2466474A Division CA2466474C (en) | 2001-11-13 | 2002-11-13 | Compositions comprising spa-1, spa-2 and spa-3, polypeptides and related uses |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2784450A1 CA2784450A1 (en) | 2003-05-22 |
| CA2784450C true CA2784450C (en) | 2016-09-13 |
Family
ID=23293077
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2784450A Expired - Fee Related CA2784450C (en) | 2001-11-13 | 2002-11-13 | Polypeptides of pseudomonas aeruginosa |
| CA2466474A Expired - Fee Related CA2466474C (en) | 2001-11-13 | 2002-11-13 | Compositions comprising spa-1, spa-2 and spa-3, polypeptides and related uses |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2466474A Expired - Fee Related CA2466474C (en) | 2001-11-13 | 2002-11-13 | Compositions comprising spa-1, spa-2 and spa-3, polypeptides and related uses |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7459165B2 (enExample) |
| EP (1) | EP1458752A2 (enExample) |
| JP (2) | JP4481646B2 (enExample) |
| AU (2) | AU2002340683C1 (enExample) |
| CA (2) | CA2784450C (enExample) |
| ES (1) | ES2431318T3 (enExample) |
| WO (1) | WO2003042240A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090208535A1 (en) * | 2004-06-28 | 2009-08-20 | Proteome Systems Intellectual Property Pty Ltd | Novel Methods of Diagnosis of Treatment of P. Aeruginosa Infection and Reagents Therefor |
| WO2006086330A2 (en) * | 2005-02-08 | 2006-08-17 | Id Biomedical Corporation Of Quebec C.O.B. As Glaxosmithkline Biologicals North America | Pharmaceutical compositions |
| US20100028415A1 (en) * | 2005-04-12 | 2010-02-04 | Haynes Barton F | Method of Inducing Neutralizing Antibodies to Human Immunodeficiency Virus |
| US7781166B2 (en) * | 2006-03-31 | 2010-08-24 | Marshall University Research Corporation | Methods of detecting and controlling mucoid pseudomonas biofilm production |
| SG189957A1 (en) * | 2010-11-05 | 2013-06-28 | Morphotek Inc | Folate receptor alpha as a diagnostic and prognostic marker for folate receptor alpha-expressing cancers |
| BR112013016254A2 (pt) * | 2010-12-23 | 2017-07-11 | Intercell Austria Ag | agentes oprf/i e seu uso em pacientes hospitalizados e outros |
| WO2015048635A1 (en) | 2013-09-27 | 2015-04-02 | Duke University | Mper-liposome conjugates and uses thereof |
| EP3236995A4 (en) * | 2014-12-23 | 2018-07-18 | University of Maryland, Baltimore | Muc1 decoy peptides for treatment and prevention of bacterial infections |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4425437A (en) | 1979-11-05 | 1984-01-10 | Genentech, Inc. | Microbial polypeptide expression vehicle |
| US4431739A (en) | 1979-11-05 | 1984-02-14 | Genentech, Inc. | Transformant bacterial culture capable of expressing heterologous protein |
| US4338397A (en) | 1980-04-11 | 1982-07-06 | President And Fellows Of Harvard College | Mature protein synthesis |
| DE3718591A1 (de) * | 1987-06-03 | 1988-12-15 | Behringwerke Ag | Aeusseres membranprotein f von pseudomonas aeruginosa |
| US5591838A (en) * | 1993-02-12 | 1997-01-07 | Board Of Regents, The University Of Texas System | Detection of conversion to mucoidy in pseudomonas aeruginosa infecting cystic fibrosis patients |
| ATE190657T1 (de) * | 1994-12-16 | 2000-04-15 | Chiron Behring Gmbh & Co | Immunogenes hybridprotein oprf-oprl erhältlich aus membranproteinen von pseudomonas aeruginosa |
| US6551795B1 (en) * | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
| WO1999057142A2 (en) | 1998-05-06 | 1999-11-11 | The Governors Of The University Of Alberta | Vaccine for $i(pseudomonas aeruginosa) |
| GB9915419D0 (en) * | 1999-07-01 | 1999-09-01 | Cortecs Uk Ltd | Antigens |
| GB9928676D0 (en) * | 1999-12-03 | 2000-02-02 | Provalis Uk Ltd | Pseudomonas aeruginosa antigens |
| JP4355786B2 (ja) * | 2001-01-26 | 2009-11-04 | エムシーダブリユー リサーチ フオンデーシヨン インコーポレーテツド | シュードモナスｖ抗原を用いる免疫化のための方法および組成物 |
-
2002
- 2002-11-13 WO PCT/CA2002/001740 patent/WO2003042240A2/en not_active Ceased
- 2002-11-13 ES ES06022429T patent/ES2431318T3/es not_active Expired - Lifetime
- 2002-11-13 CA CA2784450A patent/CA2784450C/en not_active Expired - Fee Related
- 2002-11-13 JP JP2003544075A patent/JP4481646B2/ja not_active Expired - Fee Related
- 2002-11-13 AU AU2002340683A patent/AU2002340683C1/en not_active Ceased
- 2002-11-13 EP EP02774222A patent/EP1458752A2/en not_active Withdrawn
- 2002-11-13 CA CA2466474A patent/CA2466474C/en not_active Expired - Fee Related
- 2002-11-13 US US10/495,455 patent/US7459165B2/en not_active Expired - Fee Related
-
2009
- 2009-06-23 AU AU2009202507A patent/AU2009202507C1/en not_active Ceased
-
2010
- 2010-01-28 JP JP2010016179A patent/JP5636194B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003042240A3 (en) | 2004-07-01 |
| US7459165B2 (en) | 2008-12-02 |
| WO2003042240A2 (en) | 2003-05-22 |
| AU2009202507B2 (en) | 2011-03-17 |
| CA2466474A1 (en) | 2003-05-22 |
| AU2002340683C1 (en) | 2009-11-12 |
| US20050107597A1 (en) | 2005-05-19 |
| AU2009202507A1 (en) | 2009-07-16 |
| JP5636194B2 (ja) | 2014-12-03 |
| JP2010166913A (ja) | 2010-08-05 |
| CA2466474C (en) | 2012-10-09 |
| JP4481646B2 (ja) | 2010-06-16 |
| CA2784450A1 (en) | 2003-05-22 |
| EP1458752A2 (en) | 2004-09-22 |
| AU2009202507C1 (en) | 2011-09-15 |
| ES2431318T3 (es) | 2013-11-26 |
| JP2005524387A (ja) | 2005-08-18 |
| AU2002340683B2 (en) | 2009-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20130107 |
|
| MKLA | Lapsed |
Effective date: 20181113 |