CA2781754C - Diagnostic method for detecting acute kidney injury using heat shock protein 72 as a sensitive biomarker - Google Patents

Diagnostic method for detecting acute kidney injury using heat shock protein 72 as a sensitive biomarker Download PDF

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Publication number
CA2781754C
CA2781754C CA2781754A CA2781754A CA2781754C CA 2781754 C CA2781754 C CA 2781754C CA 2781754 A CA2781754 A CA 2781754A CA 2781754 A CA2781754 A CA 2781754A CA 2781754 C CA2781754 C CA 2781754C
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CA
Canada
Prior art keywords
biomarker
hsp72
injury
renal
aki
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CA2781754A
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English (en)
French (fr)
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CA2781754A1 (en
Inventor
Norma Araceli Bobadilla Sandoval
Jonatan Barrera Chimal
Original Assignee
Universidad Nacional Autonoma de Mexico
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Publication of CA2781754A1 publication Critical patent/CA2781754A1/en
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA2781754A 2009-11-23 2010-11-23 Diagnostic method for detecting acute kidney injury using heat shock protein 72 as a sensitive biomarker Expired - Fee Related CA2781754C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
MXMX/A/2009/012633 2009-11-23
MX2009012633A MX2009012633A (es) 2009-11-23 2009-11-23 Metodo de diagnostico para detectar la lesion renal aguda a traves del uso de la proteina de choque termico de 72 kda como un biomarcador sensible.
PCT/MX2010/000138 WO2011062469A2 (es) 2009-11-23 2010-11-23 Método de diagnóstico para detectar la lesión renal aguda a través del uso de la proteína de choque térmico de 72 kda como un biomarcador sensible

Publications (2)

Publication Number Publication Date
CA2781754A1 CA2781754A1 (en) 2011-05-26
CA2781754C true CA2781754C (en) 2019-09-03

Family

ID=44060228

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2781754A Expired - Fee Related CA2781754C (en) 2009-11-23 2010-11-23 Diagnostic method for detecting acute kidney injury using heat shock protein 72 as a sensitive biomarker

Country Status (8)

Country Link
US (1) US20130065239A1 (https=)
EP (1) EP2506016B1 (https=)
JP (1) JP5755657B2 (https=)
CN (1) CN102762985B (https=)
CA (1) CA2781754C (https=)
ES (1) ES2549610T3 (https=)
MX (1) MX2009012633A (https=)
WO (1) WO2011062469A2 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011149962A1 (en) 2010-05-24 2011-12-01 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
NZ605698A (en) 2010-06-23 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN103874923B (zh) * 2011-08-26 2016-09-14 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物
CN102879584A (zh) * 2012-09-26 2013-01-16 中国人民解放军军事医学科学院基础医学研究所 一种人血液hsp70抗体胶体金标检测试纸条及其制备方法
EP2925337B1 (en) 2012-11-21 2019-07-03 The Trustees of Columbia University in the City of New York Mutant ngal proteins and uses thereof
KR101468047B1 (ko) * 2013-01-16 2014-12-02 고려대학교 산학협력단 열충격단백질군의 mRNA 발현 양상 분석을 통한 사인 추정방법
US11346846B2 (en) 2017-02-06 2022-05-31 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN107045594B (zh) * 2017-04-25 2018-06-26 吉林大学 一种脊柱损伤测量中x射线标志物的数字化系统
WO2020125806A1 (en) 2018-12-17 2020-06-25 Shanghai United Imaging Intelligence Co., Ltd. Systems and methods for image segmentation
CN109754394B (zh) * 2018-12-28 2021-02-23 上海联影智能医疗科技有限公司 三维医学图像处理装置及方法
CN111007255A (zh) * 2019-12-10 2020-04-14 江苏三联生物工程有限公司 一种用于肾损伤标志物检测的蛋白芯片及其制备方法
CN116449024A (zh) * 2023-04-13 2023-07-18 武汉市第三医院 Saa1作为生物标志物在预测或诊断急性肾损伤中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4035591B2 (ja) * 2003-01-24 2008-01-23 株式会社三重ティーエルオー 血管障害病態改善剤
AU2006272913B2 (en) * 2005-07-21 2012-01-19 The Johns Hopkins University Methods of detecting and treating acute kidney injury

Also Published As

Publication number Publication date
CN102762985A (zh) 2012-10-31
EP2506016A2 (en) 2012-10-03
JP5755657B2 (ja) 2015-07-29
JP2013511735A (ja) 2013-04-04
WO2011062469A2 (es) 2011-05-26
EP2506016B1 (en) 2015-07-08
CA2781754A1 (en) 2011-05-26
CN102762985B (zh) 2015-06-17
WO2011062469A3 (es) 2011-11-24
EP2506016A4 (en) 2013-01-23
US20130065239A1 (en) 2013-03-14
MX2009012633A (es) 2011-05-24
WO2011062469A8 (es) 2012-01-12
ES2549610T3 (es) 2015-10-29

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