CA2780016C - Size-based genomic analysis - Google Patents

Size-based genomic analysis Download PDF

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Publication number
CA2780016C
CA2780016C CA2780016A CA2780016A CA2780016C CA 2780016 C CA2780016 C CA 2780016C CA 2780016 A CA2780016 A CA 2780016A CA 2780016 A CA2780016 A CA 2780016A CA 2780016 C CA2780016 C CA 2780016C
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nucleic acid
chromosome
size
acid molecules
biological sample
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French (fr)
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CA2780016A1 (en
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Yuk Ming Dennis Lo
Kwan Chee Chan
Wenli Zheng
Wai Kwun Rossa Chiu
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Chinese University of Hong Kong
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Chinese University of Hong Kong
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/10—Ploidy or copy number detection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA2780016A 2009-11-06 2010-11-05 Size-based genomic analysis Active CA2780016C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US25907609P 2009-11-06 2009-11-06
US61/259,076 2009-11-06
US36039910P 2010-06-30 2010-06-30
US61/360,399 2010-06-30
PCT/EP2010/066935 WO2011054936A1 (en) 2009-11-06 2010-11-05 Size-based genomic analysis

Publications (2)

Publication Number Publication Date
CA2780016A1 CA2780016A1 (en) 2011-05-12
CA2780016C true CA2780016C (en) 2017-09-19

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Family Applications (1)

Application Number Title Priority Date Filing Date
CA2780016A Active CA2780016C (en) 2009-11-06 2010-11-05 Size-based genomic analysis

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US (4) US8620593B2 (enExample)
EP (3) EP3406737B1 (enExample)
JP (2) JP5770737B2 (enExample)
CN (2) CN102791881B (enExample)
AU (1) AU2010317019B2 (enExample)
CA (1) CA2780016C (enExample)
EA (1) EA034241B1 (enExample)
ES (1) ES3026544T3 (enExample)
IL (1) IL219545A (enExample)
MX (2) MX2012005217A (enExample)
TW (1) TWI445854B (enExample)
WO (1) WO2011054936A1 (enExample)

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TW201129736A (en) 2011-09-01
US20180237858A1 (en) 2018-08-23
CN107312844B (zh) 2021-01-22
EP3406737B1 (en) 2023-05-31
EP2496713B1 (en) 2018-07-18
MX2012005217A (es) 2012-07-23
AU2010317019B2 (en) 2014-10-30
CA2780016A1 (en) 2011-05-12
JP2015165805A (ja) 2015-09-24
CN107312844A (zh) 2017-11-03
EP4212630B1 (en) 2025-05-07
IL219545A0 (en) 2012-06-28
US9982300B2 (en) 2018-05-29
EP4212630C0 (en) 2025-05-07
EA201200701A1 (ru) 2012-12-28
JP5770737B2 (ja) 2015-08-26
TWI445854B (zh) 2014-07-21
US20110276277A1 (en) 2011-11-10
US8620593B2 (en) 2013-12-31
US20220282332A1 (en) 2022-09-08
EP4212630A1 (en) 2023-07-19
CN102791881B (zh) 2017-08-08
AU2010317019A1 (en) 2012-05-31
ES3026544T3 (en) 2025-06-11
US11365448B2 (en) 2022-06-21
US20140080720A1 (en) 2014-03-20
JP6001721B2 (ja) 2016-10-05
BR112012010708A2 (pt) 2016-03-29
IL219545A (en) 2015-02-26
CN102791881A (zh) 2012-11-21
EP3406737A1 (en) 2018-11-28
WO2011054936A1 (en) 2011-05-12
JP2013509870A (ja) 2013-03-21
EA034241B1 (ru) 2020-01-21
MX357692B (es) 2018-07-19
EP2496713A1 (en) 2012-09-12

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