CA2775124A1 - Combination - Google Patents
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- Publication number
- CA2775124A1 CA2775124A1 CA2775124A CA2775124A CA2775124A1 CA 2775124 A1 CA2775124 A1 CA 2775124A1 CA 2775124 A CA2775124 A CA 2775124A CA 2775124 A CA2775124 A CA 2775124A CA 2775124 A1 CA2775124 A1 CA 2775124A1
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- Prior art keywords
- chloro
- methyl
- administered
- compound
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| TWI505828B (zh) | 2010-12-20 | 2015-11-01 | 葛蘭素史克智慧財產（第二）有限公司 | 新穎醫藥組成物 |
| US9682082B2 (en) * | 2011-04-01 | 2017-06-20 | Genentech, Inc. | Combinations of AKT and MEK inhibitor compounds, and methods of use |
| EP2913048A1 (en) | 2014-02-27 | 2015-09-02 | ratiopharm GmbH | Pharmaceutical composition comprising trametinib |
| CN111201023A (zh) * | 2017-08-11 | 2020-05-26 | 启码策有限公司 | 用于靶向癌症中的多个突变的药物组合物 |
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| SI1301472T1 (sl) * | 2000-07-19 | 2014-05-30 | Warner-Lambert Company Llc | Oksigenirani estri 4-jodo fenilamino benzihidroksamskih kislin |
| US7378423B2 (en) * | 2004-06-11 | 2008-05-27 | Japan Tobacco Inc. | Pyrimidine compound and medical use thereof |
| DE602005004286T2 (de) * | 2004-06-11 | 2009-01-02 | Japan Tobacco Inc. | 5-amino-2,4,7-trioxo-3,4,7,8-tetrahydro-2h-pyridoä2,3-düpyrimidinderivate und verwandte verbindungen zur behandlung von krebs |
| JP3821154B1 (ja) * | 2005-03-16 | 2006-09-13 | いすゞ自動車株式会社 | 排気ガス浄化方法及び排気ガス浄化システム |
| UY30892A1 (es) * | 2007-02-07 | 2008-09-02 | Smithkline Beckman Corp | Inhibidores de la actividad akt |
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2010
- 2010-09-23 ES ES10819435.8T patent/ES2527625T3/es active Active
- 2010-09-23 EP EP10819435.8A patent/EP2480084B1/en active Active
- 2010-09-23 US US13/497,576 patent/US20120322817A1/en not_active Abandoned
- 2010-09-23 CN CN201080052971.0A patent/CN102770026B/zh not_active Expired - Fee Related
- 2010-09-23 BR BR112012006693A patent/BR112012006693A2/pt not_active IP Right Cessation
- 2010-09-23 CA CA2775124A patent/CA2775124A1/en not_active Abandoned
- 2010-09-23 JP JP2012531018A patent/JP2013505939A/ja not_active Ceased
- 2010-09-23 WO PCT/US2010/049946 patent/WO2011038082A1/en not_active Ceased
- 2010-09-23 MX MX2012003546A patent/MX2012003546A/es active IP Right Grant
- 2010-09-23 AU AU2010298277A patent/AU2010298277B2/en not_active Ceased
- 2010-09-23 KR KR1020127010303A patent/KR20120099219A/ko not_active Ceased
- 2010-09-23 EA EA201270445A patent/EA021951B1/ru not_active IP Right Cessation
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2012
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- 2012-03-23 ZA ZA2012/02173A patent/ZA201202173B/en unknown
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2014
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2015
- 2015-12-18 JP JP2015246931A patent/JP2016106092A/ja active Pending
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| Publication number | Publication date |
|---|---|
| KR20120099219A (ko) | 2012-09-07 |
| CN102770026B (zh) | 2015-04-01 |
| EP2480084A4 (en) | 2013-02-20 |
| ES2527625T3 (es) | 2015-01-27 |
| IL218797A0 (en) | 2012-06-28 |
| EA021951B1 (ru) | 2015-10-30 |
| JP2013505939A (ja) | 2013-02-21 |
| WO2011038082A1 (en) | 2011-03-31 |
| AU2010298277A1 (en) | 2012-04-19 |
| IL218797A (en) | 2014-11-30 |
| ZA201202173B (en) | 2012-11-28 |
| US20120322817A1 (en) | 2012-12-20 |
| BR112012006693A2 (pt) | 2015-09-08 |
| EP2480084B1 (en) | 2014-11-12 |
| AU2010298277B2 (en) | 2014-07-03 |
| JP2016106092A (ja) | 2016-06-16 |
| CN102770026A (zh) | 2012-11-07 |
| US20150094321A1 (en) | 2015-04-02 |
| EA201270445A1 (ru) | 2013-03-29 |
| MX2012003546A (es) | 2012-09-07 |
| EP2480084A1 (en) | 2012-08-01 |
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