CA2767167A1 - Purification of monoclonal antibodies - Google Patents

Purification of monoclonal antibodies Download PDF

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Publication number
CA2767167A1
CA2767167A1 CA2767167A CA2767167A CA2767167A1 CA 2767167 A1 CA2767167 A1 CA 2767167A1 CA 2767167 A CA2767167 A CA 2767167A CA 2767167 A CA2767167 A CA 2767167A CA 2767167 A1 CA2767167 A1 CA 2767167A1
Authority
CA
Canada
Prior art keywords
antibody
antibodies
solid support
array
bead
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2767167A
Other languages
English (en)
French (fr)
Inventor
Qian Gao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of CA2767167A1 publication Critical patent/CA2767167A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00Methods of screening libraries
    • C40B30/04Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2767167A 2009-07-08 2010-07-07 Purification of monoclonal antibodies Abandoned CA2767167A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22398409P 2009-07-08 2009-07-08
US61/223,984 2009-07-08
PCT/US2010/041146 WO2011005818A1 (en) 2009-07-08 2010-07-07 Purification of monoclonal antibodies

Publications (1)

Publication Number Publication Date
CA2767167A1 true CA2767167A1 (en) 2011-01-13

Family

ID=43427937

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2767167A Abandoned CA2767167A1 (en) 2009-07-08 2010-07-07 Purification of monoclonal antibodies

Country Status (6)

Country Link
US (1) US9395370B2 (enExample)
EP (1) EP2452196B1 (enExample)
JP (1) JP5739419B2 (enExample)
CN (1) CN102472747B (enExample)
CA (1) CA2767167A1 (enExample)
WO (1) WO2011005818A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2542576T (pt) 2010-03-02 2016-07-14 Seattle Genetics Inc Métodos para rastreio de anticorpos
CN104034899B (zh) * 2014-07-01 2015-12-30 上海理工大学 一种食源性致病菌杂交瘤细胞快速筛选抗原宏阵列

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2718849B1 (fr) * 1994-04-14 1996-06-14 Pasteur Sanofi Diagnostics Procédé d'immunodosage de l'antithrombine III activée par un glycosaminoglycane, anticorps monoclonaux correspondants et leur procédé d'obtention.
JPH1072500A (ja) * 1996-06-18 1998-03-17 Mitsui Petrochem Ind Ltd 分子量約20000のヒト成長ホルモンに特異的に反応するモノクローナル抗体、該抗体を産生する細胞株及び該抗体を用いる分子量約20000のヒト成長ホルモンの免疫測定方法
US5892687A (en) 1997-03-12 1999-04-06 Ambit Design Systems, Inc. Don't-- care logic
US7271009B1 (en) 1997-11-18 2007-09-18 Bio-Rad Laboratories, Inc. Multi-analyte diagnostic test for thyroid disorders
US6770445B1 (en) * 1999-02-26 2004-08-03 Pacific Northwest Research Institute Methods and compositions for diagnosing carcinomas
IT1308253B1 (it) 1999-03-16 2001-12-10 Molteni L E C Dei Flii Alitti Dosatore di precisione per liquidi.
US6531283B1 (en) * 2000-06-20 2003-03-11 Molecular Staging, Inc. Protein expression profiling
JP2004537712A (ja) * 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
US20030143612A1 (en) * 2001-07-18 2003-07-31 Pointilliste, Inc. Collections of binding proteins and tags and uses thereof for nested sorting and high throughput screening
US20030044849A1 (en) * 2001-08-22 2003-03-06 Steven Kessler Methods for screening monoclonal antibodies on heterogeneous antigen substrates
WO2005116076A2 (en) 2004-01-26 2005-12-08 Debiovision Inc. Neoplasm-specific polypeptides and their uses
JP4680607B2 (ja) * 2005-01-14 2011-05-11 公立大学法人大阪府立大学 シガトキシン類を認識するモノクローナル抗体、およびそれを用いるシガトキシン類検出キット
US20070237713A1 (en) * 2006-04-04 2007-10-11 Fan Rong A PCan065 Antibody Compositions and Methods of Use
PE20130588A1 (es) 2007-02-02 2013-05-21 Amgen Inc Hepcidina, antagonistas de la hepcidina y metodos de uso

Also Published As

Publication number Publication date
EP2452196A1 (en) 2012-05-16
EP2452196A4 (en) 2013-03-06
US20110009287A1 (en) 2011-01-13
JP2012532876A (ja) 2012-12-20
EP2452196B1 (en) 2017-09-06
WO2011005818A1 (en) 2011-01-13
US9395370B2 (en) 2016-07-19
CN102472747B (zh) 2015-04-29
CN102472747A (zh) 2012-05-23
JP5739419B2 (ja) 2015-06-24

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150625

FZDE Dead

Effective date: 20180709