CA2764366C - Imaging of myelin basic protein - Google Patents

Imaging of myelin basic protein Download PDF

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Publication number
CA2764366C
CA2764366C CA2764366A CA2764366A CA2764366C CA 2764366 C CA2764366 C CA 2764366C CA 2764366 A CA2764366 A CA 2764366A CA 2764366 A CA2764366 A CA 2764366A CA 2764366 C CA2764366 C CA 2764366C
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CA
Canada
Prior art keywords
formula
agent
myelin
group
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2764366A
Other languages
English (en)
French (fr)
Other versions
CA2764366A1 (en
Inventor
Cristina Abucay Tan Hehir
Tiberiu Mircea Siclovan
Nicole Evelyn Barnhardt
Kenneth Michael Fish
Randall Lee Carter
Bruce Fletcher Johnson
Rong Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Electric Co
Original Assignee
General Electric Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/478,300 external-priority patent/US8617515B2/en
Application filed by General Electric Co filed Critical General Electric Co
Publication of CA2764366A1 publication Critical patent/CA2764366A1/en
Application granted granted Critical
Publication of CA2764366C publication Critical patent/CA2764366C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
    • A61K49/10—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA2764366A 2009-06-04 2010-06-03 Imaging of myelin basic protein Active CA2764366C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12/478,300 US8617515B2 (en) 2009-06-04 2009-06-04 Imaging of myelin basic protein
US12/478,300 2009-06-04
US12/694,820 2010-01-27
US12/694,820 US20100310456A1 (en) 2009-06-04 2010-01-27 Imaging of myelin basic protein
PCT/US2010/037237 WO2010141704A2 (en) 2009-06-04 2010-06-03 Imaging of myelin basic protein

Publications (2)

Publication Number Publication Date
CA2764366A1 CA2764366A1 (en) 2010-12-09
CA2764366C true CA2764366C (en) 2018-12-04

Family

ID=42983984

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2764366A Active CA2764366C (en) 2009-06-04 2010-06-03 Imaging of myelin basic protein

Country Status (7)

Country Link
US (1) US20100310456A1 (de)
EP (1) EP2437792B1 (de)
JP (1) JP5897461B2 (de)
CN (1) CN102802672B (de)
CA (1) CA2764366C (de)
DK (1) DK2437792T3 (de)
WO (1) WO2010141704A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8846955B2 (en) * 2009-08-24 2014-09-30 National Institute Of Information And Communications Technology Second-order nonlinear optical compound and nonlinear optical element comprising the same
MX336896B (es) * 2009-12-23 2016-02-05 Piramal Imaging Sa Formulaciones adecuadas para la generacion de imagenes pet con agentes pet hidrofobicos.
NL2007714C2 (en) * 2011-11-04 2013-05-08 Academisch Ziekenhuis Leiden Lumc Imaging ligands.
US8977331B2 (en) 2012-12-13 2015-03-10 General Electric Company Systems and methods for nerve imaging
US10744212B2 (en) * 2016-03-14 2020-08-18 General Electric Company Topical application of nerve labeling dyes for image-guided surgery
JP6876067B2 (ja) * 2016-04-04 2021-05-26 ゼネラル・エレクトリック・カンパニイ 神経調節のための技術
CN111885914B (zh) * 2017-10-27 2022-05-13 投资健康有限责任公司 使用芴衍生物制造扩增的造血干细胞的组合物和方法
WO2025235234A1 (en) * 2024-05-07 2025-11-13 Edison Innovations, Llc Non-invasive nerve imaging using ultrasound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6229024B1 (en) * 1998-01-23 2001-05-08 Laurence C. Schmued Method for detecting neuronal degeneration and anionic fluorescein homologue stains therefor
US6372451B1 (en) * 2000-04-24 2002-04-16 Laurence C. Schmued Histochemical labeling stain for myelin in brain tissue
US20030232016A1 (en) * 2002-04-17 2003-12-18 Russell Heinrich Nerve identification and sparing method
JP4774946B2 (ja) * 2005-06-21 2011-09-21 日本電産サンキョー株式会社 不揮発性メモリ及びそれを用いた電子機器装置
EP2038261A2 (de) * 2006-06-22 2009-03-25 Mallinckrodt Inc. Pyrazinderivate mit erweiterter konjugation und anwendung
JP2010520238A (ja) * 2007-03-01 2010-06-10 マリンクロット インコーポレイテッド 統合された光活性低分子および統合された光活性低分子使用
EP2198040B1 (de) * 2007-08-31 2018-08-15 Case Western Reserve University In-vivo-abbildung von myelin

Also Published As

Publication number Publication date
EP2437792B1 (de) 2015-10-21
AU2010256533A1 (en) 2011-12-15
CA2764366A1 (en) 2010-12-09
JP5897461B2 (ja) 2016-03-30
WO2010141704A2 (en) 2010-12-09
CN102802672A (zh) 2012-11-28
JP2012528880A (ja) 2012-11-15
US20100310456A1 (en) 2010-12-09
WO2010141704A3 (en) 2011-02-17
CN102802672B (zh) 2015-12-16
EP2437792A2 (de) 2012-04-11
DK2437792T3 (en) 2016-01-11

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