CA2761886A1 - Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab - Google Patents

Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab Download PDF

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Publication number
CA2761886A1
CA2761886A1 CA2761886A CA2761886A CA2761886A1 CA 2761886 A1 CA2761886 A1 CA 2761886A1 CA 2761886 A CA2761886 A CA 2761886A CA 2761886 A CA2761886 A CA 2761886A CA 2761886 A1 CA2761886 A1 CA 2761886A1
Authority
CA
Canada
Prior art keywords
antibodies
fragments
cell line
human
staphylococcus aureus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2761886A
Other languages
English (en)
French (fr)
Inventor
Knut Ohlsen
Udo Lorenz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Julius Maximilians Universitaet Wuerzburg
Original Assignee
Julius Maximilians Universitaet Wuerzburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Julius Maximilians Universitaet Wuerzburg filed Critical Julius Maximilians Universitaet Wuerzburg
Publication of CA2761886A1 publication Critical patent/CA2761886A1/en
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
CA2761886A 2009-05-18 2010-05-18 Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab Abandoned CA2761886A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17913309P 2009-05-18 2009-05-18
US61/179,133 2009-05-18
PCT/EP2010/056827 WO2010133600A1 (en) 2009-05-18 2010-05-18 Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab

Publications (1)

Publication Number Publication Date
CA2761886A1 true CA2761886A1 (en) 2010-11-25

Family

ID=42316060

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2761886A Abandoned CA2761886A1 (en) 2009-05-18 2010-05-18 Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab

Country Status (13)

Country Link
US (3) US8609102B2 (https=)
EP (1) EP2432804B1 (https=)
JP (2) JP5882892B2 (https=)
CN (1) CN102695724B (https=)
AU (1) AU2010251156C1 (https=)
BR (1) BRPI1010911A2 (https=)
CA (1) CA2761886A1 (https=)
ES (1) ES2537437T3 (https=)
MX (1) MX2011012248A (https=)
PL (1) PL2432804T3 (https=)
PT (1) PT2432804E (https=)
RU (1) RU2560415C2 (https=)
WO (1) WO2010133600A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011012248A (es) * 2009-05-18 2012-02-29 Univ Wuerzburg J Maximilians Anticuerpos o sus fragmentos dirigidos contra un epitope de staphylococcus aureus de isaa o isab.
JP2014534169A (ja) * 2011-09-23 2014-12-18 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓエピトープ結合部位を形成するペプチドまたはペプチドの配置
EP3080160B1 (en) * 2013-12-13 2022-07-06 Rijksuniversiteit Groningen Antibodies against staphylococcus aureus and uses thereof
JP7525471B2 (ja) 2018-07-24 2024-07-30 メディミューン，エルエルシー Ｓ．アウレウス（Ｓ．ａｕｒｅｕｓ）クランピング因子Ａ（ＣｌｆＡ）に対する抗体
KR102341805B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균에 특이적으로 반응하는 항-IsaA G4 항체 및 이의 용도
KR102341804B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균을 억제하는 항-IsaA F10 항체 및 이의 용도
JP7750490B2 (ja) * 2019-12-17 2025-10-07 国立大学法人三重大学 線維症の評価および処置のための方法および組成物
WO2022250205A1 (ko) * 2021-05-25 2022-12-01 주식회사 하울바이오 항-IsaA F10 항체의 아토피 피부염 예방 및 개선 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4238806A1 (en) 1991-11-18 1993-05-27 Dainabot Co Methicillin-resistant staphylococcus aureus (MRSA)detection method - by detection of MRSA penicillin binding protein (PBP)2 antigen-antibody complex, and synthetic MRSA PBP2 peptides
FR2746398B1 (fr) * 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
RU2144190C1 (ru) * 1998-01-13 2000-01-10 Катханов Али Муратович Способ диагностики стафилококковой инфекции
GB0014907D0 (en) * 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
GB0127983D0 (en) * 2001-11-22 2002-01-16 Neutec Pharma Plc Treatment of micro-organism infection
WO2006076058A1 (en) * 2005-01-10 2006-07-20 Nabi Biopharmaceuticals Method of treating staphylococcus aureus infection
MX2011012248A (es) * 2009-05-18 2012-02-29 Univ Wuerzburg J Maximilians Anticuerpos o sus fragmentos dirigidos contra un epitope de staphylococcus aureus de isaa o isab.

Also Published As

Publication number Publication date
EP2432804A1 (en) 2012-03-28
CN102695724B (zh) 2016-08-24
EP2432804B1 (en) 2015-02-25
CN102695724A (zh) 2012-09-26
AU2010251156C1 (en) 2015-02-05
BRPI1010911A2 (pt) 2019-09-24
AU2010251156B2 (en) 2014-10-09
US20120100151A1 (en) 2012-04-26
US20160109449A1 (en) 2016-04-21
US9658230B2 (en) 2017-05-23
JP2016047828A (ja) 2016-04-07
PL2432804T3 (pl) 2015-08-31
WO2010133600A1 (en) 2010-11-25
JP2012527423A (ja) 2012-11-08
RU2011146424A (ru) 2013-06-27
US8609102B2 (en) 2013-12-17
RU2560415C2 (ru) 2015-08-20
US20140072570A1 (en) 2014-03-13
ES2537437T3 (es) 2015-06-08
US9260511B2 (en) 2016-02-16
AU2010251156A1 (en) 2011-11-24
PT2432804E (pt) 2015-06-25
MX2011012248A (es) 2012-02-29
JP5882892B2 (ja) 2016-03-09

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Legal Events

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EEER Examination request

Effective date: 20150219

FZDE Discontinued

Effective date: 20180518