CA2755364C - Biosensor with predetermined dose response curve and method of manufacturing - Google Patents
Biosensor with predetermined dose response curve and method of manufacturing Download PDFInfo
- Publication number
- CA2755364C CA2755364C CA2755364A CA2755364A CA2755364C CA 2755364 C CA2755364 C CA 2755364C CA 2755364 A CA2755364 A CA 2755364A CA 2755364 A CA2755364 A CA 2755364A CA 2755364 C CA2755364 C CA 2755364C
- Authority
- CA
- Canada
- Prior art keywords
- biosensor
- biosensors
- dose
- effective area
- electrical pattern
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 68
- 231100000673 dose–response relationship Toxicity 0.000 title claims abstract description 65
- 238000000034 method Methods 0.000 claims description 60
- 239000000758 substrate Substances 0.000 claims description 30
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 230000004075 alteration Effects 0.000 claims description 2
- 238000010030 laminating Methods 0.000 claims description 2
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 21
- 239000012491 analyte Substances 0.000 description 28
- 239000000523 sample Substances 0.000 description 22
- 238000012360 testing method Methods 0.000 description 22
- 238000012937 correction Methods 0.000 description 16
- 230000008859 change Effects 0.000 description 10
- 239000004020 conductor Substances 0.000 description 8
- 230000004044 response Effects 0.000 description 8
- 239000012530 fluid Substances 0.000 description 7
- 230000006870 function Effects 0.000 description 6
- 238000005259 measurement Methods 0.000 description 6
- 238000003070 Statistical process control Methods 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 238000009792 diffusion process Methods 0.000 description 4
- 238000000608 laser ablation Methods 0.000 description 4
- 230000003287 optical effect Effects 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 239000013060 biological fluid Substances 0.000 description 3
- 230000000875 corresponding effect Effects 0.000 description 3
- 238000003869 coulometry Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- 238000004082 amperometric method Methods 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 2
- 230000005611 electricity Effects 0.000 description 2
- 238000002848 electrochemical method Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000004313 potentiometry Methods 0.000 description 2
- 238000003908 quality control method Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 238000007650 screen-printing Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000006978 adaptation Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 239000002800 charge carrier Substances 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000001066 destructive effect Effects 0.000 description 1
- 238000009658 destructive testing Methods 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 150000004677 hydrates Chemical class 0.000 description 1
- 238000002847 impedance measurement Methods 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000004611 spectroscopical analysis Methods 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000004832 voltammetry Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
- B29C65/74—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by welding and severing, or by joining and severing, the severing being performed in the area to be joined, next to the area to be joined, in the joint area or next to the joint area
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/4875—Details of handling test elements, e.g. dispensing or storage, not specific to a particular test method
- G01N33/48771—Coding of information, e.g. calibration data, lot number
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Mechanical Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/413.778 | 2009-03-30 | ||
| US12/413,778 US8608937B2 (en) | 2009-03-30 | 2009-03-30 | Biosensor with predetermined dose response curve and method of manufacturing |
| PCT/EP2010/001857 WO2010112168A1 (en) | 2009-03-30 | 2010-03-25 | Biosensor with predetermined dose response curve and method of manufacturing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2755364A1 CA2755364A1 (en) | 2010-10-07 |
| CA2755364C true CA2755364C (en) | 2014-09-23 |
Family
ID=42226635
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2755364A Expired - Fee Related CA2755364C (en) | 2009-03-30 | 2010-03-25 | Biosensor with predetermined dose response curve and method of manufacturing |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8608937B2 (enExample) |
| EP (2) | EP2414825B1 (enExample) |
| JP (1) | JP5363645B2 (enExample) |
| KR (1) | KR101293361B1 (enExample) |
| CN (1) | CN102369437B (enExample) |
| CA (1) | CA2755364C (enExample) |
| ES (1) | ES2415856T3 (enExample) |
| MX (1) | MX2011009896A (enExample) |
| PL (1) | PL2414825T3 (enExample) |
| WO (1) | WO2010112168A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1486102A (en) * | 2000-11-07 | 2002-05-21 | Immunovaccine Technologies Inc | Vaccines with enhanced immune response and methods for their preparation |
| KR100918027B1 (ko) * | 2009-02-19 | 2009-09-18 | 주식회사 올메디쿠스 | 코드전극을 구비한 바이오센서와 이의 제조방법, 및 이의 센서 정보 획득 방법 |
| US8940141B2 (en) * | 2010-05-19 | 2015-01-27 | Lifescan Scotland Limited | Analytical test strip with an electrode having electrochemically active and inert areas of a predetermined size and distribution |
| US10168313B2 (en) * | 2013-03-15 | 2019-01-01 | Agamatrix, Inc. | Analyte detection meter and associated method of use |
| WO2016011308A1 (en) | 2014-07-17 | 2016-01-21 | Siemens Healthcare Diagnostics Inc. | Sensor array |
| EP3156790A1 (en) | 2015-10-15 | 2017-04-19 | ARKRAY, Inc. | Biosensor and manufacturing method of biosensor |
| JP6754259B2 (ja) * | 2015-10-15 | 2020-09-09 | アークレイ株式会社 | バイオセンサ、及びその製造方法 |
| FI128124B (en) * | 2016-04-25 | 2019-10-15 | Teknologian Tutkimuskeskus Vtt Oy | Optical sensor, systems and procedures |
| CN110161095B (zh) * | 2018-02-12 | 2024-02-23 | 杭州微策生物技术股份有限公司 | 一种生物传感器电阻调节激光系统及其方法 |
| WO2021138405A1 (en) * | 2019-12-30 | 2021-07-08 | Roche Diabetes Care, Inc. | Temperature compensated biosensors and methods of manufacture and use thereof |
| KR102782040B1 (ko) * | 2020-02-25 | 2025-03-13 | 엘지전자 주식회사 | 횡류팬 |
Family Cites Families (49)
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| US4008448A (en) | 1975-10-03 | 1977-02-15 | Polaroid Corporation | Solenoid with selectively arrestible plunger movement |
| US4233029A (en) | 1978-10-25 | 1980-11-11 | Eastman Kodak Company | Liquid transport device and method |
| US4225410A (en) | 1978-12-04 | 1980-09-30 | Technicon Instruments Corporation | Integrated array of electrochemical sensors |
| US4323536A (en) | 1980-02-06 | 1982-04-06 | Eastman Kodak Company | Multi-analyte test device |
| DE3228542A1 (de) | 1982-07-30 | 1984-02-02 | Siemens AG, 1000 Berlin und 8000 München | Verfahren zur bestimmung der konzentration elektrochemisch umsetzbarer stoffe |
| US5509410A (en) | 1983-06-06 | 1996-04-23 | Medisense, Inc. | Strip electrode including screen printing of a single layer |
| US5682884A (en) | 1983-05-05 | 1997-11-04 | Medisense, Inc. | Strip electrode with screen printing |
| SE8305704D0 (sv) | 1983-10-18 | 1983-10-18 | Leo Ab | Cuvette |
| US5108564A (en) | 1988-03-15 | 1992-04-28 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
| US5128015A (en) | 1988-03-15 | 1992-07-07 | Tall Oak Ventures | Method and apparatus for amperometric diagnostic analysis |
| DE68924026T3 (de) | 1988-03-31 | 2008-01-10 | Matsushita Electric Industrial Co., Ltd., Kadoma | Biosensor und dessen herstellung. |
| ATE124990T1 (de) | 1989-12-15 | 1995-07-15 | Boehringer Mannheim Corp | Redox-vermittlungs-reagenz und biosensor. |
| US5243516A (en) | 1989-12-15 | 1993-09-07 | Boehringer Mannheim Corporation | Biosensing instrument and method |
| JP2541081B2 (ja) * | 1992-08-28 | 1996-10-09 | 日本電気株式会社 | バイオセンサ及びバイオセンサの製造・使用方法 |
| US5366609A (en) | 1993-06-08 | 1994-11-22 | Boehringer Mannheim Corporation | Biosensing meter with pluggable memory key |
| US5431800A (en) * | 1993-11-05 | 1995-07-11 | The University Of Toledo | Layered electrodes with inorganic thin films and method for producing the same |
| US5762770A (en) * | 1994-02-21 | 1998-06-09 | Boehringer Mannheim Corporation | Electrochemical biosensor test strip |
| US5437999A (en) | 1994-02-22 | 1995-08-01 | Boehringer Mannheim Corporation | Electrochemical sensor |
| KR0151203B1 (ko) * | 1994-12-08 | 1998-12-01 | 이헌조 | 다중전극형 바이오센서 |
| US5628890A (en) | 1995-09-27 | 1997-05-13 | Medisense, Inc. | Electrochemical sensor |
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| JP3365184B2 (ja) | 1996-01-10 | 2003-01-08 | 松下電器産業株式会社 | バイオセンサ |
| TR200000200T2 (tr) * | 1997-07-22 | 2000-05-22 | Kyoto Daiichi Kagaku Co., Ltd. | Konsantrasyon ölçüm cihazı, konsantrasyon ölçüm cihazı için test şeridi, biyosensor sistemi, ve test şeridi üzerinde terminal oluşturma yöntemi |
| US6054039A (en) | 1997-08-18 | 2000-04-25 | Shieh; Paul | Determination of glycoprotein and glycosylated hemoglobin in blood |
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| US5997817A (en) | 1997-12-05 | 1999-12-07 | Roche Diagnostics Corporation | Electrochemical biosensor test strip |
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| US7418285B2 (en) * | 2004-12-29 | 2008-08-26 | Abbott Laboratories | Analyte test sensor and method of manufacturing the same |
| US7866026B1 (en) * | 2006-08-01 | 2011-01-11 | Abbott Diabetes Care Inc. | Method for making calibration-adjusted sensors |
| US7312042B1 (en) * | 2006-10-24 | 2007-12-25 | Abbott Diabetes Care, Inc. | Embossed cell analyte sensor and methods of manufacture |
-
2009
- 2009-03-30 US US12/413,778 patent/US8608937B2/en active Active
-
2010
- 2010-03-25 ES ES10712005T patent/ES2415856T3/es active Active
- 2010-03-25 EP EP10712005.7A patent/EP2414825B1/en active Active
- 2010-03-25 CN CN201080014452.5A patent/CN102369437B/zh not_active Expired - Fee Related
- 2010-03-25 MX MX2011009896A patent/MX2011009896A/es active IP Right Grant
- 2010-03-25 KR KR1020117022864A patent/KR101293361B1/ko not_active Expired - Fee Related
- 2010-03-25 JP JP2012502496A patent/JP5363645B2/ja not_active Expired - Fee Related
- 2010-03-25 PL PL10712005T patent/PL2414825T3/pl unknown
- 2010-03-25 CA CA2755364A patent/CA2755364C/en not_active Expired - Fee Related
- 2010-03-25 WO PCT/EP2010/001857 patent/WO2010112168A1/en not_active Ceased
- 2010-03-25 EP EP13000782.6A patent/EP2594939B1/en active Active
-
2013
- 2013-07-10 US US13/938,791 patent/US8685229B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2594939B1 (en) | 2020-12-02 |
| ES2415856T3 (es) | 2013-07-29 |
| KR101293361B1 (ko) | 2013-08-07 |
| MX2011009896A (es) | 2011-09-30 |
| CA2755364A1 (en) | 2010-10-07 |
| HK1167893A1 (zh) | 2012-12-14 |
| CN102369437A (zh) | 2012-03-07 |
| EP2414825B1 (en) | 2013-04-17 |
| WO2010112168A1 (en) | 2010-10-07 |
| JP5363645B2 (ja) | 2013-12-11 |
| EP2594939A1 (en) | 2013-05-22 |
| CN102369437B (zh) | 2015-09-09 |
| JP2012522226A (ja) | 2012-09-20 |
| US8608937B2 (en) | 2013-12-17 |
| US20100243441A1 (en) | 2010-09-30 |
| EP2414825A1 (en) | 2012-02-08 |
| US20130292033A1 (en) | 2013-11-07 |
| US8685229B2 (en) | 2014-04-01 |
| PL2414825T3 (pl) | 2013-09-30 |
| KR20110122220A (ko) | 2011-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20210325 |