CA2754335C - Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essentially consisting of vp3 - Google Patents

Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essentially consisting of vp3 Download PDF

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CA2754335C
CA2754335C CA2754335A CA2754335A CA2754335C CA 2754335 C CA2754335 C CA 2754335C CA 2754335 A CA2754335 A CA 2754335A CA 2754335 A CA2754335 A CA 2754335A CA 2754335 C CA2754335 C CA 2754335C
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seq
nucleic acid
protein
capsid
aav
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French (fr)
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CA2754335A1 (en
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Florian Sonntag
Juergen Kleinschmidt
Markus Hoerer
Kerstin Lux
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German Cancer Research Center
Medigene AG
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
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    • C12N2750/14123—Virus like particles [VLP]
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    • C12N2750/00011—Details
    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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CA2754335A 2009-03-04 2010-03-04 Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essentially consisting of vp3 Active CA2754335C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US15743609P 2009-03-04 2009-03-04
US61/157,436 2009-03-04
US30620510P 2010-02-19 2010-02-19
US61/306,205 2010-02-19
PCT/EP2010/001343 WO2010099960A2 (en) 2009-03-04 2010-03-04 Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essential consisting of vp3

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CA2754335A1 CA2754335A1 (en) 2010-09-10
CA2754335C true CA2754335C (en) 2019-12-24

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CA2754335A Active CA2754335C (en) 2009-03-04 2010-03-04 Assembly activating protein (aap) and its use for the manufacture of parvovirus particles essentially consisting of vp3

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US (3) US9464119B2 (cg-RX-API-DMAC10.html)
EP (1) EP2403867B1 (cg-RX-API-DMAC10.html)
JP (2) JP2012519008A (cg-RX-API-DMAC10.html)
CN (1) CN102341406B (cg-RX-API-DMAC10.html)
BR (1) BRPI1013364A2 (cg-RX-API-DMAC10.html)
CA (1) CA2754335C (cg-RX-API-DMAC10.html)
DK (1) DK2403867T3 (cg-RX-API-DMAC10.html)
ES (1) ES2742180T3 (cg-RX-API-DMAC10.html)
MX (2) MX345729B (cg-RX-API-DMAC10.html)
PL (1) PL2403867T3 (cg-RX-API-DMAC10.html)
PT (1) PT2403867T (cg-RX-API-DMAC10.html)
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JP2012519008A (ja) 2012-08-23
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PT2403867T (pt) 2019-08-29
CA2754335A1 (en) 2010-09-10
US9464119B2 (en) 2016-10-11
ES2742180T3 (es) 2020-02-13
US20120135022A1 (en) 2012-05-31
US11267847B2 (en) 2022-03-08
CN102341406A (zh) 2012-02-01
JP2016063810A (ja) 2016-04-28
MX345729B (es) 2017-02-14
DK2403867T3 (da) 2019-08-12
WO2010099960A3 (en) 2011-01-13
EP2403867A2 (en) 2012-01-11
WO2010099960A2 (en) 2010-09-10
US20200087352A1 (en) 2020-03-19
MX2011009193A (es) 2011-12-16
EP2403867B1 (en) 2019-05-22
US20170226160A1 (en) 2017-08-10
JP6151328B2 (ja) 2017-06-21
CN102341406B (zh) 2016-06-08
PL2403867T3 (pl) 2019-12-31

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