CA2753713A1 - Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer - Google Patents

Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer Download PDF

Info

Publication number
CA2753713A1
CA2753713A1 CA2753713A CA2753713A CA2753713A1 CA 2753713 A1 CA2753713 A1 CA 2753713A1 CA 2753713 A CA2753713 A CA 2753713A CA 2753713 A CA2753713 A CA 2753713A CA 2753713 A1 CA2753713 A1 CA 2753713A1
Authority
CA
Canada
Prior art keywords
glycodelin
monoclonal antibody
seq
antibody
ovarian cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2753713A
Other languages
English (en)
French (fr)
Inventor
Robert L. Cheek
Eric P. Dixon
Timothy J. Fischer
John W. Groelke
Steven L. Knapp
Stephen G. Simkins
Clark M. Whitehead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TriPath Imaging Inc
Original Assignee
TriPath Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TriPath Imaging Inc filed Critical TriPath Imaging Inc
Publication of CA2753713A1 publication Critical patent/CA2753713A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57449Specifically defined cancers of ovaries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Biotechnology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2753713A 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer Abandoned CA2753713A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15815909P 2009-03-06 2009-03-06
US61/158,159 2009-03-06
PCT/US2010/026319 WO2010102177A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Publications (1)

Publication Number Publication Date
CA2753713A1 true CA2753713A1 (en) 2010-09-10

Family

ID=42101610

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2753713A Abandoned CA2753713A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Country Status (6)

Country Link
US (2) US8252904B2 (enExample)
EP (1) EP2403875A1 (enExample)
JP (1) JP2012524521A (enExample)
AU (1) AU2010221188A1 (enExample)
CA (1) CA2753713A1 (enExample)
WO (1) WO2010102177A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2737317A2 (en) * 2011-07-28 2014-06-04 The Trustees Of The University Of Pennsylvania Methods for diagnosing cancer by characterization of tumor cells associated with pleural or serous fluids
CA2845536A1 (en) 2011-08-15 2013-02-21 Amplimmune, Inc. Anti-b7-h4 antibodies and their uses
SG11201504764SA (en) 2012-12-19 2015-07-30 Amplimmune Inc Anti-human b7-h4 antibodies and their uses
GB201604468D0 (en) * 2016-03-16 2016-04-27 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
CN106199012A (zh) * 2016-06-30 2016-12-07 深圳市亚辉龙生物科技股份有限公司 抑制素b化学发光免疫检测试剂盒及其制备方法
CN106053836A (zh) * 2016-06-30 2016-10-26 深圳市亚辉龙生物科技股份有限公司 抗子宫内膜抗体化学发光免疫检测试剂盒及其制备方法
JP7211604B2 (ja) * 2017-12-05 2023-01-24 国立大学法人金沢大学 膠芽腫マーカー及びその使用
US20190346457A1 (en) 2018-03-13 2019-11-14 Government Of The Unted States, As Represented By The Secretary Of The Army Assays and methods for detection and targeted treatment of hydrosalpinx
EA202092684A1 (ru) 2018-08-27 2021-03-11 Ридженерон Фармасьютикалз, Инк. Применение рамановской спектроскопии для последующей очистки
CN116496394B (zh) * 2022-01-26 2024-07-23 东莞市朋志生物科技有限公司 抗s100蛋白的抗体、检测s100蛋白的试剂和试剂盒

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
CA1247080A (en) 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ES2139598T3 (es) 1990-07-10 2000-02-16 Medical Res Council Procedimientos para la produccion de miembros de parejas de union especifica.
GB9022543D0 (en) 1990-10-17 1990-11-28 Wellcome Found Antibody production
WO1992009690A2 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with altered binding properties
ATE439435T1 (de) 1991-03-01 2009-08-15 Dyax Corp Chimäres protein mit mikroprotein mit zwei oder mehr disulfidbindungen und ausgestaltungen davon
EP1471142B1 (en) 1991-04-10 2008-11-19 The Scripps Research Institute Heterodimeric receptor libraries using phagemids
CA2064544A1 (en) 1991-06-28 1992-12-29 Anthony E. Bolton Immune cell proliferation inhibitors
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
CA2115811A1 (en) 1993-02-17 1994-08-18 Claus Krebber A method for in vivo selection of ligand-binding proteins
US5830698A (en) 1997-03-14 1998-11-03 Idec Pharmaceuticals Corporation Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
DE19807389C2 (de) 1998-02-21 2000-08-17 Max Delbrueck Centrum Monoklonale Antikörper gegen Glycodelin A, Verfahren zu ihrer Herstellung und ihre Verwendung
US20020058292A1 (en) 2000-12-08 2002-05-16 Dillon Davin C. Ovarian tumor antigen and methods of use therefor
US20030087250A1 (en) * 2001-03-14 2003-05-08 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
AU2005228026B2 (en) 2004-03-24 2011-03-24 Tripath Imaging, Inc. Methods and compositions for the detection of cervical disease
US7595380B2 (en) 2005-04-27 2009-09-29 Tripath Imaging, Inc. Monoclonal antibodies and methods for their use in the detection of cervical disease
MX2008009592A (es) * 2006-01-27 2008-09-08 Tripath Imaging Inc Metodos y composiciones para identificar pacientes con una probabilidad incrementada de tener cancer de ovario.
AU2008226587A1 (en) * 2007-03-09 2008-09-18 Tripath Imaging, Inc. HE4 monoclonal antibodies and methods for their use
US20090087849A1 (en) * 2007-09-06 2009-04-02 Tripath Imaging, Inc. Nucleic acid-based methods and compositions for the detection of ovarian cancer

Also Published As

Publication number Publication date
US8252904B2 (en) 2012-08-28
WO2010102177A1 (en) 2010-09-10
US8476033B2 (en) 2013-07-02
JP2012524521A (ja) 2012-10-18
AU2010221188A1 (en) 2011-10-20
US20100227343A1 (en) 2010-09-09
EP2403875A1 (en) 2012-01-11
US20130022998A1 (en) 2013-01-24

Similar Documents

Publication Publication Date Title
US8252904B2 (en) Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer
US20100227335A1 (en) Matrix metalloproteinase-7 (mmp-7) monoclonal antibodies and methods for their use in the detection of ovarian cancer
US7846692B2 (en) HE4 monoclonal antibodies and methods for their use
JP6554152B2 (ja) 葉酸受容体アルファ発現癌の診断および予後マーカーとしての葉酸受容体アルファ
CA2809368C (en) Methods for detecting anti-he4 antibodies and methods of diagnosis and/or prognosis of conditions associated with he4-expressing cells
CN114705858A (zh) 用于评估癌症发生的风险的组合物和方法
CN109517062A (zh) 能够结合linc00266-1多肽的抗体
AU2015215008B2 (en) Composition and method for detecting malignant neoplastic disease
CN111303289B (zh) 抗人Tn型糖基化MUC1抗体及其用途
KR20110091423A (ko) 항―tmap/ckap2 항체를 포함하는 암의 예후 진단용 조성물
HK40073614A (en) Compositions and methods for assessing the risk of cancer occurrence
CA3009768C (en) Compositions and methods for assessing the risk of cancer occurrence
HK1262633A1 (en) Compositions and methods for assessing the risk of cancer occurrence
HK1262633B (zh) 用於评估癌症发生的风险的组合物和方法
EA043033B1 (ru) Способ оценки риска возникновения рака, соответствующие набор, блок хранения данных и обрабатывающая система

Legal Events

Date Code Title Description
FZDE Dead

Effective date: 20150305