CA2751275A1 - Use of docosahexaenoic acid in treating mild cognitive impairment - Google Patents

Use of docosahexaenoic acid in treating mild cognitive impairment Download PDF

Info

Publication number
CA2751275A1
CA2751275A1 CA2751275A CA2751275A CA2751275A1 CA 2751275 A1 CA2751275 A1 CA 2751275A1 CA 2751275 A CA2751275 A CA 2751275A CA 2751275 A CA2751275 A CA 2751275A CA 2751275 A1 CA2751275 A1 CA 2751275A1
Authority
CA
Canada
Prior art keywords
dha
acid
less
unit dose
per day
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2751275A
Other languages
English (en)
French (fr)
Inventor
Karin Yurko-Mauro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
Martek Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Biosciences Corp filed Critical Martek Biosciences Corp
Publication of CA2751275A1 publication Critical patent/CA2751275A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
CA2751275A 2009-02-02 2010-02-02 Use of docosahexaenoic acid in treating mild cognitive impairment Abandoned CA2751275A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14931009P 2009-02-02 2009-02-02
US61/149,310 2009-02-02
US18354809P 2009-06-02 2009-06-02
US61/183,548 2009-06-02
PCT/US2010/022952 WO2010088700A1 (en) 2009-02-02 2010-02-02 Methods for improving cognitive function and decreasing heart rate

Publications (1)

Publication Number Publication Date
CA2751275A1 true CA2751275A1 (en) 2010-08-05

Family

ID=42041547

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2751275A Abandoned CA2751275A1 (en) 2009-02-02 2010-02-02 Use of docosahexaenoic acid in treating mild cognitive impairment

Country Status (8)

Country Link
US (2) US20100203123A1 (cg-RX-API-DMAC7.html)
EP (2) EP2939671A1 (cg-RX-API-DMAC7.html)
JP (5) JP2012516852A (cg-RX-API-DMAC7.html)
CN (3) CN104042600A (cg-RX-API-DMAC7.html)
AU (2) AU2016201382A1 (cg-RX-API-DMAC7.html)
CA (1) CA2751275A1 (cg-RX-API-DMAC7.html)
HK (1) HK1202243A1 (cg-RX-API-DMAC7.html)
WO (1) WO2010088700A1 (cg-RX-API-DMAC7.html)

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US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
US20110177061A1 (en) * 2009-07-10 2011-07-21 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid
CN103732223A (zh) * 2011-05-19 2014-04-16 加利福尼亚大学董事会 用于认知能力下降的医疗食品
US8168611B1 (en) 2011-09-29 2012-05-01 Chemo S.A. France Compositions, kits and methods for nutrition supplementation
US20130084272A1 (en) * 2011-09-29 2013-04-04 Philippe Perrin Compositions, kits and methods for nutritional supplementation with twelve carbon chain fatty acids and twelve carbon chain acylglycerols
BR112015023088A2 (pt) * 2013-03-15 2017-11-21 Genspera Inc método para preparar um composto, e, composto
CN115109804A (zh) 2013-12-20 2022-09-27 玛拉可再生能源公司 从微生物中回收油的方法
TR201503136A2 (tr) * 2015-03-16 2016-09-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dronedaron ve esansiyel yağ asitlerinin farmasötik kompozisyonları.
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
CN110168071A (zh) 2016-12-22 2019-08-23 玛拉可再生能源公司 用于使用真核微生物产生富含dha、棕榈酸和蛋白质的生物质的方法
JP7101087B2 (ja) * 2018-09-05 2022-07-14 株式会社 伊藤園 軽度認知障害に対する緑茶成分の有効性評価方法
FR3092968B1 (fr) * 2019-02-22 2021-05-21 Microphyt Complement alimentaire
CN114555074A (zh) * 2019-08-08 2022-05-27 斯威本科技大学 长链多不饱和脂肪酸的用途
US12359230B2 (en) 2020-04-03 2025-07-15 MARA Renewables Corporation Microbial oils with high levels of omega-3 fatty acids
DE102020115238A1 (de) * 2020-06-09 2021-12-09 Pm-International Ag Nahrungsergänzungsmittel und Nahrungsmittel
WO2022006496A1 (en) * 2020-07-02 2022-01-06 Pear Therapeutics, Inc. Systems, methods, and devices for generating and administering digital therapeutic placebos and shams
JP2024504116A (ja) * 2021-01-15 2024-01-30 ケンブリッジ コグニション リミテッド 周術期神経認知障害及び／又はウイルス感染後認知障害の個人を特定する方法及びシステム
EP4637824A1 (en) * 2023-01-18 2025-10-29 Bioventures, Llc Method of preventing and treating alzheimer's disease and related dementias with drugs inhibiting the interaction between 14-3-3g protein and hexokinase-1 protein
JP2025079778A (ja) * 2023-11-10 2025-05-22 ダイドーグループホールディングス株式会社 生理機能改善用の組成物
WO2025100476A1 (ja) * 2023-11-10 2025-05-15 国立大学法人京都大学 生理機能改善用の組成物

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5407957A (en) 1990-02-13 1995-04-18 Martek Corporation Production of docosahexaenoic acid by dinoflagellates
US20050027004A1 (en) * 1993-06-09 2005-02-03 Martek Biosciences Corporation Methods of treating senile dementia and Alzheimer's diseases using docosahexaenoic acid and arachidonic acid compositions
AU693450B2 (en) * 1993-06-09 1998-07-02 Martek Biosciences Corporation Methods and pharmaceutical compositions useful for treating neurological disorders
CA2197187C (en) 1994-08-16 2007-03-27 Bernd Best Process for extracting native products which are not water-soluble from native substance mixtures by means of centrifugal force
DE69637953D1 (de) * 1995-04-17 2009-07-30 Nat Inst Of Advanced Ind Scien Hoch ungesättigte fettsäurenproduzierende mikroorganismen und verfahren zur herstellung von hoch ungesättigten fettsäuren durch verwendung dieser mikroorganismen
JP3985035B2 (ja) * 1995-09-14 2007-10-03 独立行政法人産業技術総合研究所 （ｎ−６）系ドコサペンタエン酸含有油脂ならびに該油脂の製造方法および用途
ATE273373T1 (de) 1999-02-26 2004-08-15 Martek Biosciences Corp Verfahren zum abtrennen von einem docosahexaensäure enthaltenden triglyerid aus einem triglyceridgemisch
WO2001051598A1 (en) 2000-01-11 2001-07-19 Monsanto Technology Llc Process for making an enriched mixture of polyunsaturated fatty acid esters
ATE485385T1 (de) 2000-01-19 2010-11-15 Martek Biosciences Corp Lösungsmittelfreies extraktionsverfahren
ATE447332T1 (de) 2000-04-12 2009-11-15 Gea Westfalia Separator Gmbh Verfahren zur fraktionierung von öl- und polar lipid-enthaltenden rohstoffen unter verwendung von alkohol und zentrifugation
JP2004536059A (ja) 2001-05-14 2004-12-02 マーテック バイオサイエンシズ ボールダー コーポレーション 微生物、遺伝的に改変された植物種子および海洋生物由来のω−３および／またはω−６高度不飽和脂肪酸を含有する極性脂質の豊富な画分の生成および使用
WO2002092073A1 (en) 2001-05-14 2002-11-21 Martek Biosciences Corporation Production and use of a polar lipid-rich fraction containing stearidonic acid and gamma linolenic acid from plant seeds and microbes
AU2002320251A1 (en) * 2001-07-05 2003-01-21 Vital Basics, Inc. Compositions for improving mental performance
EP2266525B1 (en) 2002-05-03 2012-07-11 Martek Biosciences Corporation High quality lipids and methods for producing by enzymatic liberation from biomass
US8324276B2 (en) * 2005-01-24 2012-12-04 Pronova Biopharma Norge As Fatty acid composition for treatment of alzheimer's disease and cognitive dysfunction
JP5503846B2 (ja) * 2005-01-24 2014-05-28 プロノヴァ・バイオファーマ・ノルゲ・アーエス アミロイドーシス関連疾患の治療のための医療品又は食料品の製造における、ｄｈａを含有する脂肪酸組成物の使用
WO2006116755A2 (en) * 2005-04-28 2006-11-02 Trustees Of Tufts College Synergitic effects of docosahexaenoic acid (dha) and carotenoid absorption of cognitive function
HUE031206T2 (en) * 2005-05-23 2017-06-28 Massachusetts Inst Technology Formulations and methods of application containing PUFA
MX336435B (es) * 2005-07-08 2016-01-19 Dsm Ip Assets Bv Acidos grasos poliinsaturados para el tratamiento de demencia y condiciones relacionadas con pre-demencia.
WO2009002145A1 (en) * 2007-06-26 2008-12-31 N.V. Nutricia Lipid composition for improving function of brain functioning
US20090023808A1 (en) 2007-06-29 2009-01-22 Martek Biosciences Corporation Production and Purification of Esters of Polyunsaturated Fatty Acids
US20110177061A1 (en) * 2009-07-10 2011-07-21 Martek Biosciences Corporation Methods of treating and preventing neurological disorders using docosahexaenoic acid

Also Published As

Publication number Publication date
JP2022059063A (ja) 2022-04-12
EP2391361A1 (en) 2011-12-07
JP2012516852A (ja) 2012-07-26
WO2010088700A1 (en) 2010-08-05
EP2939671A1 (en) 2015-11-04
JP2015143248A (ja) 2015-08-06
US20100203123A1 (en) 2010-08-12
CN102365087A (zh) 2012-02-29
US20130172412A1 (en) 2013-07-04
AU2010207929A1 (en) 2011-09-22
HK1202243A1 (en) 2015-09-25
AU2016201382A1 (en) 2016-03-24
AU2017245327A1 (en) 2017-11-02
CN104042600A (zh) 2014-09-17
JP2020050675A (ja) 2020-04-02
JP2018104477A (ja) 2018-07-05
CN108324706A (zh) 2018-07-27

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150130

FZDE Discontinued

Effective date: 20190204