CA2743537C - Benzimidazole derivatives and their use for modulating the gabaa receptor complex - Google Patents
Benzimidazole derivatives and their use for modulating the gabaa receptor complex Download PDFInfo
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- CA2743537C CA2743537C CA2743537A CA2743537A CA2743537C CA 2743537 C CA2743537 C CA 2743537C CA 2743537 A CA2743537 A CA 2743537A CA 2743537 A CA2743537 A CA 2743537A CA 2743537 C CA2743537 C CA 2743537C
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- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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- GTZCVFVGUGFEME-UHFFFAOYSA-N trans-aconitic acid Natural products OC(=O)CC(C(O)=O)=CC(O)=O GTZCVFVGUGFEME-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11494908P | 2008-11-14 | 2008-11-14 | |
| DKPA200801588 | 2008-11-14 | ||
| DKPA200801588 | 2008-11-14 | ||
| US61/114,949 | 2008-11-14 | ||
| PCT/EP2009/065125 WO2010055132A1 (en) | 2008-11-14 | 2009-11-13 | Benzimidazole derivatives and their use for modulating the gabaa receptor complex |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2743537A1 CA2743537A1 (en) | 2010-05-20 |
| CA2743537C true CA2743537C (en) | 2016-09-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2743537A Expired - Fee Related CA2743537C (en) | 2008-11-14 | 2009-11-13 | Benzimidazole derivatives and their use for modulating the gabaa receptor complex |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8492408B2 (enExample) |
| EP (1) | EP2365971B1 (enExample) |
| JP (1) | JP5712135B2 (enExample) |
| CN (1) | CN102216290A (enExample) |
| AR (1) | AR074121A1 (enExample) |
| CA (1) | CA2743537C (enExample) |
| MX (1) | MX2011004738A (enExample) |
| TW (1) | TW201029986A (enExample) |
| WO (1) | WO2010055132A1 (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201607943A (zh) * | 2013-12-19 | 2016-03-01 | 拜耳製藥公司 | 作為ｅｐ４配體之新穎苯并咪唑衍生物 |
| LT3849976T (lt) | 2018-09-13 | 2023-02-10 | Saniona A/S | Gaba a receptoriaus ligandas |
| WO2025141131A1 (en) | 2023-12-27 | 2025-07-03 | Saniona A/S | A gabaa receptor ligand and the use thereof in medicine, in particular in the treatment of epilepsy |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK40192D0 (da) * | 1992-03-26 | 1992-03-26 | Neurosearch As | Imidazolforbindelser, deres fremstilling og anvendelse |
| US5554630A (en) | 1993-03-24 | 1996-09-10 | Neurosearch A/S | Benzimidazole compounds |
| AU675484B2 (en) | 1993-03-24 | 1997-02-06 | Neurosearch A/S | Benzimidazole compounds, their use and preparation |
| WO2004087690A2 (en) * | 2003-04-03 | 2004-10-14 | Neurosearch A/S | Benzimidazole derivatives and their use for modulating the gaba-a receptor complex |
| TWI391381B (zh) | 2006-03-24 | 2013-04-01 | Neurosearch As | 新穎的苯并咪唑衍生物、含有其之醫藥組成物、及其於製造藥物之用途 |
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2009
- 2009-11-05 TW TW098137554A patent/TW201029986A/zh unknown
- 2009-11-13 AR ARP090104402A patent/AR074121A1/es unknown
- 2009-11-13 EP EP09756152.6A patent/EP2365971B1/en not_active Not-in-force
- 2009-11-13 CA CA2743537A patent/CA2743537C/en not_active Expired - Fee Related
- 2009-11-13 JP JP2011536027A patent/JP5712135B2/ja not_active Expired - Fee Related
- 2009-11-13 WO PCT/EP2009/065125 patent/WO2010055132A1/en not_active Ceased
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- 2009-11-13 US US13/129,066 patent/US8492408B2/en not_active Expired - Fee Related
- 2009-11-13 CN CN2009801454687A patent/CN102216290A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20110257230A1 (en) | 2011-10-20 |
| CN102216290A (zh) | 2011-10-12 |
| MX2011004738A (es) | 2011-10-24 |
| CA2743537A1 (en) | 2010-05-20 |
| TW201029986A (en) | 2010-08-16 |
| US8492408B2 (en) | 2013-07-23 |
| AR074121A1 (es) | 2010-12-22 |
| WO2010055132A1 (en) | 2010-05-20 |
| EP2365971B1 (en) | 2017-10-25 |
| EP2365971A1 (en) | 2011-09-21 |
| JP2012508727A (ja) | 2012-04-12 |
| JP5712135B2 (ja) | 2015-05-07 |
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