CA2743177A1 - Peptidomimetic macrocycles with improved properties - Google Patents
Peptidomimetic macrocycles with improved properties Download PDFInfo
- Publication number
- CA2743177A1 CA2743177A1 CA2743177A CA2743177A CA2743177A1 CA 2743177 A1 CA2743177 A1 CA 2743177A1 CA 2743177 A CA2743177 A CA 2743177A CA 2743177 A CA2743177 A CA 2743177A CA 2743177 A1 CA2743177 A1 CA 2743177A1
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- Prior art keywords
- polypeptide
- crosslinked
- cross
- crosslink
- helical
- Prior art date
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- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
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| US11750808P | 2008-11-24 | 2008-11-24 | |
| US61/117,508 | 2008-11-24 | ||
| PCT/US2009/065824 WO2010060112A1 (en) | 2008-11-24 | 2009-11-24 | Peptidomimetic macrocycles with improved properties |
Publications (1)
| Publication Number | Publication Date |
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| CA2743177A1 true CA2743177A1 (en) | 2010-05-27 |
Family
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| CA2743177A Abandoned CA2743177A1 (en) | 2008-11-24 | 2009-11-24 | Peptidomimetic macrocycles with improved properties |
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| EP (1) | EP2352507A4 (OSRAM) |
| JP (3) | JP2012509902A (OSRAM) |
| CN (1) | CN102223891A (OSRAM) |
| AU (2) | AU2009316288B2 (OSRAM) |
| BR (1) | BRPI0920899A2 (OSRAM) |
| CA (1) | CA2743177A1 (OSRAM) |
| IL (1) | IL212748A (OSRAM) |
| WO (1) | WO2010060112A1 (OSRAM) |
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| US7192713B1 (en) | 1999-05-18 | 2007-03-20 | President And Fellows Of Harvard College | Stabilized compounds having secondary structure motifs |
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| WO2005118620A2 (en) * | 2004-05-27 | 2005-12-15 | New York University | Methods for preparing internally constraied peptides and peptidomimetics |
| AU2007333846B2 (en) * | 2006-12-14 | 2014-01-23 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| US7981998B2 (en) * | 2006-12-14 | 2011-07-19 | Aileron Therapeutics, Inc. | Bis-sulfhydryl macrocyclization systems |
| PL2118123T3 (pl) | 2007-01-31 | 2016-06-30 | Dana Farber Cancer Inst Inc | Stabilizowane peptydy p53 i ich zastosowania |
| EP2114428B1 (en) | 2007-02-23 | 2012-10-31 | Aileron Therapeutics, Inc. | Triazole linked macrocyclic peptides |
| KR101525754B1 (ko) | 2007-03-28 | 2015-06-09 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
| EP2247298B1 (en) * | 2007-12-31 | 2016-08-31 | New York University | Control of viral-host membrane fusion with hydrogen bond surrogate-based artificial helices |
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| EP2376100B1 (en) | 2009-01-14 | 2017-10-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
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2009
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- 2009-11-24 JP JP2011537728A patent/JP2012509902A/ja active Pending
- 2009-11-24 BR BRPI0920899A patent/BRPI0920899A2/pt not_active Application Discontinuation
- 2009-11-24 CA CA2743177A patent/CA2743177A1/en not_active Abandoned
- 2009-11-24 WO PCT/US2009/065824 patent/WO2010060112A1/en not_active Ceased
- 2009-11-24 EP EP09828398A patent/EP2352507A4/en not_active Withdrawn
- 2009-11-24 US US12/625,533 patent/US9458202B2/en not_active Expired - Fee Related
- 2009-11-24 CN CN2009801468497A patent/CN102223891A/zh active Pending
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2011
- 2011-05-05 IL IL212748A patent/IL212748A/en active IP Right Grant
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2015
- 2015-01-26 JP JP2015012176A patent/JP6194325B2/ja not_active Expired - Fee Related
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2016
- 2016-08-10 US US15/233,796 patent/US20170212125A1/en not_active Abandoned
- 2016-08-19 AU AU2016216698A patent/AU2016216698B2/en not_active Ceased
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2017
- 2017-06-16 JP JP2017118484A patent/JP2017186363A/ja not_active Withdrawn
Also Published As
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| WO2010060112A1 (en) | 2010-05-27 |
| US20100298201A1 (en) | 2010-11-25 |
| CN102223891A (zh) | 2011-10-19 |
| IL212748A0 (en) | 2011-07-31 |
| US20170212125A1 (en) | 2017-07-27 |
| US9458202B2 (en) | 2016-10-04 |
| AU2016216698B2 (en) | 2018-02-22 |
| JP2015091868A (ja) | 2015-05-14 |
| AU2009316288B2 (en) | 2016-05-19 |
| BRPI0920899A2 (pt) | 2016-04-26 |
| JP2017186363A (ja) | 2017-10-12 |
| AU2009316288A1 (en) | 2010-05-27 |
| AU2016216698A1 (en) | 2016-09-08 |
| EP2352507A1 (en) | 2011-08-10 |
| JP2012509902A (ja) | 2012-04-26 |
| EP2352507A4 (en) | 2012-04-25 |
| IL212748A (en) | 2017-10-31 |
| JP6194325B2 (ja) | 2017-09-06 |
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