CA2743032A1 - Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes - Google Patents
Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes Download PDFInfo
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- CA2743032A1 CA2743032A1 CA2743032A CA2743032A CA2743032A1 CA 2743032 A1 CA2743032 A1 CA 2743032A1 CA 2743032 A CA2743032 A CA 2743032A CA 2743032 A CA2743032 A CA 2743032A CA 2743032 A1 CA2743032 A1 CA 2743032A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
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- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20070853A FI20070853A0 (fi) | 2007-11-09 | 2007-11-09 | Glykaania sitovat monoklonaaliset vasta-aineet |
| FI20070853 | 2007-11-09 | ||
| PCT/FI2008/050643 WO2009060129A1 (en) | 2007-11-09 | 2008-11-10 | Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2743032A1 true CA2743032A1 (en) | 2009-05-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2743032A Abandoned CA2743032A1 (en) | 2007-11-09 | 2008-11-10 | Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100292095A1 (enExample) |
| EP (1) | EP2209809A4 (enExample) |
| JP (1) | JP2011504099A (enExample) |
| AU (1) | AU2008324073A1 (enExample) |
| CA (1) | CA2743032A1 (enExample) |
| FI (1) | FI20070853A0 (enExample) |
| WO (1) | WO2009060129A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT110526A (pt) * | 2018-01-26 | 2019-07-26 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI20095418A0 (fi) * | 2009-04-16 | 2009-04-16 | Suomen Punainen Risti Veripalv | Kryptinen subpopulaatio |
| EP2345964A4 (en) * | 2008-10-13 | 2013-11-20 | Mitsubishi Electric Corp | CONTRACTING APPROACH, OPERATING PROGRAM, RECORDING MEDIUM AND CONTRACTING PROCESS |
| WO2013151649A1 (en) | 2012-04-04 | 2013-10-10 | Sialix Inc | Glycan-interacting compounds |
| PL2928476T3 (pl) | 2012-12-07 | 2018-07-31 | Glycomimetics, Inc. | Związki, kompozycje i sposoby wykorzystujące antagonistów e-selektyny do mobilizacji komórek hematopoietycznych |
| US9879087B2 (en) | 2014-11-12 | 2018-01-30 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| EP3218005B1 (en) | 2014-11-12 | 2023-01-04 | Seagen Inc. | Glycan-interacting compounds and methods of use |
| PT3227310T (pt) | 2014-12-03 | 2019-11-06 | Glycomimetics Inc | Inibidores heterobifuncionais de e-selectinas e recetores de quimiocina cxcr4 |
| EP3371222A1 (en) * | 2015-11-03 | 2018-09-12 | GlycoMimetics, Inc. | Methods and compositions for the production of monoclonal antibodies, hematopoietic stem cells, and methods of using the same |
| WO2017083582A1 (en) | 2015-11-12 | 2017-05-18 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| US11291678B2 (en) | 2016-03-02 | 2022-04-05 | Glycomimetics, Inc | Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin |
| US11433086B2 (en) | 2016-08-08 | 2022-09-06 | Glycomimetics, Inc. | Combination of T-cell checkpoint inhibitors with inhibitors of e-selectin or CXCR4, or with heterobifunctional inhibitors of both E-selectin and CXCR4 |
| CN109890421B (zh) | 2016-10-07 | 2023-10-20 | 糖模拟物有限公司 | 高效的多聚体e-选择蛋白拮抗剂 |
| US11401330B2 (en) | 2016-11-17 | 2022-08-02 | Seagen Inc. | Glycan-interacting compounds and methods of use |
| GB201703212D0 (en) * | 2017-02-28 | 2017-04-12 | Nat Univ Ireland Galway | The detectionm quantification and discrimination of the sialic acid N-glycolylneuraminic (Neu5Gc) acid and N-acetylneuraminic acid (Neu5gc) |
| CA3054939A1 (en) | 2017-03-03 | 2018-09-07 | Seattle Genetics, Inc. | Glycan-interacting compounds and methods of use |
| JP7272956B2 (ja) | 2017-03-15 | 2023-05-12 | グリコミメティクス， インコーポレイテッド | Ｅ－セレクチンアンタゴニストとしてのガラクトピラノシル－シクロヘキシル誘導体 |
| JP7275131B2 (ja) | 2017-11-30 | 2023-05-17 | グリコミメティクス， インコーポレイテッド | 骨髄浸潤リンパ球を動員する方法、およびその使用 |
| KR20200104889A (ko) | 2017-12-29 | 2020-09-04 | 글리코미메틱스, 인크. | E-셀렉틴 및 갈렉틴-3의 이종이기능성 억제제 |
| CA3091454A1 (en) | 2018-03-05 | 2019-09-12 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
| BR112021004444A2 (pt) * | 2018-09-10 | 2021-06-01 | Cold Spring Harbor Laboratory | métodos para tratar pancreatite |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (11)
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| US4342566A (en) * | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
| US4965198A (en) * | 1985-12-24 | 1990-10-23 | Konica Corporation | Monoclonal antibody and method of manufacturing hybridoma producing the same |
| US4949778A (en) * | 1987-12-16 | 1990-08-21 | Kawasaki Steel Corporation | Immersion nozzle for continuous casting |
| DE4208795A1 (de) * | 1992-03-19 | 1993-09-23 | Behringwerke Ag | Monoklonaler anti-gangliosid-antikoerper, seine herstellung und verwendung als tumortherapeutikum |
| EP2261255A1 (en) * | 2003-07-15 | 2010-12-15 | The Regents of The University of California | Methods for purifying sialic acid-specific antibodies and composition comprising affinity-purified antibodies |
| FI20055398A0 (fi) * | 2005-07-08 | 2005-07-08 | Suomen Punainen Risti Veripalv | Menetelmä solupopulaatioiden evaluoimiseksi |
| WO2007054622A1 (en) * | 2005-11-08 | 2007-05-18 | Suomen Punainen Risti, Veripalvelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| AU2007264846A1 (en) * | 2006-06-29 | 2008-01-03 | Glykos Finland Oy | Novel cellular glycan compositions |
| WO2008087259A1 (en) * | 2007-01-18 | 2008-07-24 | Suomen Punainen Risti, Veripalvelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| US20100047827A1 (en) * | 2007-01-18 | 2010-02-25 | Suomen Punainen Risti, Veripalvelu | Novel specific cell binders |
| CA2712556A1 (en) * | 2007-01-18 | 2008-07-24 | Glykos Finland Ltd | Novel carbohydrate from human cells and methods for analysis and modification thereof |
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2007
- 2007-11-09 FI FI20070853A patent/FI20070853A0/fi not_active Application Discontinuation
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2008
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- 2008-11-10 EP EP08847066A patent/EP2209809A4/en not_active Withdrawn
- 2008-11-10 CA CA2743032A patent/CA2743032A1/en not_active Abandoned
- 2008-11-10 AU AU2008324073A patent/AU2008324073A1/en not_active Abandoned
- 2008-11-10 WO PCT/FI2008/050643 patent/WO2009060129A1/en not_active Ceased
- 2008-11-10 JP JP2010532633A patent/JP2011504099A/ja active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT110526A (pt) * | 2018-01-26 | 2019-07-26 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
| WO2019147152A1 (en) | 2018-01-26 | 2019-08-01 | Universidade Nova De Lisboa | L2a5 antibody or functional fragment thereof against tumour antigens |
| PT110526B (pt) * | 2018-01-26 | 2021-02-04 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
Also Published As
| Publication number | Publication date |
|---|---|
| FI20070853A0 (fi) | 2007-11-09 |
| JP2011504099A (ja) | 2011-02-03 |
| EP2209809A4 (en) | 2011-03-30 |
| EP2209809A1 (en) | 2010-07-28 |
| AU2008324073A1 (en) | 2009-05-14 |
| US20100292095A1 (en) | 2010-11-18 |
| WO2009060129A1 (en) | 2009-05-14 |
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