CA2743032A1 - Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes - Google Patents
Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes Download PDFInfo
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- CA2743032A1 CA2743032A1 CA2743032A CA2743032A CA2743032A1 CA 2743032 A1 CA2743032 A1 CA 2743032A1 CA 2743032 A CA2743032 A CA 2743032A CA 2743032 A CA2743032 A CA 2743032A CA 2743032 A1 CA2743032 A1 CA 2743032A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI20070853 | 2007-11-09 | ||
| FI20070853A FI20070853A0 (fi) | 2007-11-09 | 2007-11-09 | Glykaania sitovat monoklonaaliset vasta-aineet |
| PCT/FI2008/050643 WO2009060129A1 (en) | 2007-11-09 | 2008-11-10 | Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2743032A1 true CA2743032A1 (en) | 2009-05-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2743032A Abandoned CA2743032A1 (en) | 2007-11-09 | 2008-11-10 | Human monoclonal antibodies directed to sialyl lewis c, sialyl tn and n-glycolylneuraminic acid epitopes and a method of analysis of stem cells comprising said epitopes |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20100292095A1 (enExample) |
| EP (1) | EP2209809A4 (enExample) |
| JP (1) | JP2011504099A (enExample) |
| AU (1) | AU2008324073A1 (enExample) |
| CA (1) | CA2743032A1 (enExample) |
| FI (1) | FI20070853A0 (enExample) |
| WO (1) | WO2009060129A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT110526A (pt) * | 2018-01-26 | 2019-07-26 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
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| FI20095418A0 (fi) * | 2009-04-16 | 2009-04-16 | Suomen Punainen Risti Veripalv | Kryptinen subpopulaatio |
| WO2010044131A1 (ja) * | 2008-10-13 | 2010-04-22 | 三菱電機株式会社 | リソース割り当て装置及びリソース割り当てプログラム及び記録媒体及びリソース割り当て方法 |
| WO2013151649A1 (en) | 2012-04-04 | 2013-10-10 | Sialix Inc | Glycan-interacting compounds |
| SI2928476T1 (en) | 2012-12-07 | 2018-06-29 | Glycomimetics, Inc. | COMPONENTS, INSTALLATIONS AND PROCEDURES OF THE APPLICATION OF E-SELECTINE OF ANTAGONISTS FOR THE MOBILIZATION OF HEMATOPOETIC CELLS |
| US9879087B2 (en) | 2014-11-12 | 2018-01-30 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| IL278574B2 (en) | 2014-11-12 | 2024-11-01 | Seagen Inc | Glycan-interacting compounds and methods of use |
| HUE045542T2 (hu) | 2014-12-03 | 2019-12-30 | Glycomimetics Inc | E-szelektinek és CXCR4 kemokin receptorok heterobifunkcionális inhibitorai |
| CN108350077A (zh) * | 2015-11-03 | 2018-07-31 | 糖模拟物有限公司 | 产生单克隆抗体、造血干细胞的方法和组合物以及利用所述抗体和造血干细胞的方法 |
| EP3373969A4 (en) | 2015-11-12 | 2019-08-14 | Siamab Therapeutics, Inc. | GLYCANINTERAGING COMPOUNDS AND METHOD OF USE |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| WO2018031445A1 (en) | 2016-08-08 | 2018-02-15 | Glycomimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4 |
| BR112019006642A2 (pt) | 2016-10-07 | 2019-07-02 | Glycomimetics Inc | antagonistas multiméricos de e-selectina altamente potentes |
| WO2018094143A1 (en) | 2016-11-17 | 2018-05-24 | Siamab Therapeutics, Inc. | Glycan-interacting compounds and methods of use |
| GB201703212D0 (en) * | 2017-02-28 | 2017-04-12 | Nat Univ Ireland Galway | The detectionm quantification and discrimination of the sialic acid N-glycolylneuraminic (Neu5Gc) acid and N-acetylneuraminic acid (Neu5gc) |
| BR112019018043A2 (pt) | 2017-03-03 | 2020-04-07 | Seattle Genetics Inc | método de tratamento de câncer, e, conjugado de anticorpo-fármaco |
| CA3054605A1 (en) | 2017-03-15 | 2018-09-20 | Glycomimetics, Inc. | Galactopyranosyl-cyclohexyl derivatives as e-selectin antagonists |
| EP3717013A1 (en) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| JP7304863B2 (ja) | 2017-12-29 | 2023-07-07 | グリコミメティクス， インコーポレイテッド | Ｅ－セレクチンおよびガレクチン－３のヘテロ二機能性阻害剤 |
| KR20200128025A (ko) | 2018-03-05 | 2020-11-11 | 글리코미메틱스, 인크. | 급성 골수성 백혈병 및 관련 병태의 치료 방법 |
| MX2021002761A (es) * | 2018-09-10 | 2021-05-31 | Cold Spring Harbor Laboratory | Metodos para tratar la pancreatitis. |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
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| US4342566A (en) * | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
| US4965198A (en) * | 1985-12-24 | 1990-10-23 | Konica Corporation | Monoclonal antibody and method of manufacturing hybridoma producing the same |
| US4949778A (en) * | 1987-12-16 | 1990-08-21 | Kawasaki Steel Corporation | Immersion nozzle for continuous casting |
| DE4208795A1 (de) * | 1992-03-19 | 1993-09-23 | Behringwerke Ag | Monoklonaler anti-gangliosid-antikoerper, seine herstellung und verwendung als tumortherapeutikum |
| EP2302390B1 (en) * | 2003-07-15 | 2013-06-05 | The Regents of The University of California | Methods for detecting and analyzing n-glycolylneuraminic acid (Neu5Gc) specific antibodies in biological materials |
| FI20055398A0 (fi) * | 2005-07-08 | 2005-07-08 | Suomen Punainen Risti Veripalv | Menetelmä solupopulaatioiden evaluoimiseksi |
| WO2007054620A1 (en) * | 2005-11-08 | 2007-05-18 | Suomen Punainen Risti, Veripalvelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| EP2047257A4 (en) * | 2006-06-29 | 2011-11-16 | Suomen Punainen Risti Veripalvelu | NEW CELLULAR GLYCAN COMPOSITIONS |
| EP2115461A4 (en) * | 2007-01-18 | 2010-01-13 | Suomen Punainen Risti Veripalv | NEW SPECIFIC CELL BINDERS |
| WO2008087259A1 (en) * | 2007-01-18 | 2008-07-24 | Suomen Punainen Risti, Veripalvelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| AU2008206885B2 (en) * | 2007-01-18 | 2011-02-03 | Glykos Finland Oy | Novel carbohydrate from human cells and methods for analysis and modification thereof |
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2007
- 2007-11-09 FI FI20070853A patent/FI20070853A0/fi not_active Application Discontinuation
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2008
- 2008-11-10 CA CA2743032A patent/CA2743032A1/en not_active Abandoned
- 2008-11-10 US US12/741,987 patent/US20100292095A1/en not_active Abandoned
- 2008-11-10 JP JP2010532633A patent/JP2011504099A/ja active Pending
- 2008-11-10 AU AU2008324073A patent/AU2008324073A1/en not_active Abandoned
- 2008-11-10 WO PCT/FI2008/050643 patent/WO2009060129A1/en not_active Ceased
- 2008-11-10 EP EP08847066A patent/EP2209809A4/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT110526A (pt) * | 2018-01-26 | 2019-07-26 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
| WO2019147152A1 (en) | 2018-01-26 | 2019-08-01 | Universidade Nova De Lisboa | L2a5 antibody or functional fragment thereof against tumour antigens |
| PT110526B (pt) * | 2018-01-26 | 2021-02-04 | Univ Nova De Lisboa | Anticorpo, fragmento funcional ou sonda do mesmo contra antigénios tumorais |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008324073A1 (en) | 2009-05-14 |
| WO2009060129A1 (en) | 2009-05-14 |
| US20100292095A1 (en) | 2010-11-18 |
| FI20070853A0 (fi) | 2007-11-09 |
| EP2209809A1 (en) | 2010-07-28 |
| EP2209809A4 (en) | 2011-03-30 |
| JP2011504099A (ja) | 2011-02-03 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20131113 |