CA2739705A1 - Efficient expression of truncated human rnaset2 in e. coli - Google Patents

Efficient expression of truncated human rnaset2 in e. coli Download PDF

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Publication number
CA2739705A1
CA2739705A1 CA2739705A CA2739705A CA2739705A1 CA 2739705 A1 CA2739705 A1 CA 2739705A1 CA 2739705 A CA2739705 A CA 2739705A CA 2739705 A CA2739705 A CA 2739705A CA 2739705 A1 CA2739705 A1 CA 2739705A1
Authority
CA
Canada
Prior art keywords
rnaset2
truncated
human
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2739705A
Other languages
English (en)
French (fr)
Inventor
Oded Shoseyov
Betty Schwartz
Levava Roiz
Patricia Smirnoff
Liron Nuttman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yissum Research Development Co of Hebrew University of Jerusalem
Original Assignee
Yissum Research Development Co of Hebrew University of Jerusalem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Research Development Co of Hebrew University of Jerusalem filed Critical Yissum Research Development Co of Hebrew University of Jerusalem
Publication of CA2739705A1 publication Critical patent/CA2739705A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA2739705A 2008-10-30 2009-10-29 Efficient expression of truncated human rnaset2 in e. coli Abandoned CA2739705A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19313408P 2008-10-30 2008-10-30
US61/193,134 2008-10-30
PCT/IL2009/001012 WO2010049933A1 (en) 2008-10-30 2009-10-29 Efficient expression of truncated human rnaset2 in e. coli

Publications (1)

Publication Number Publication Date
CA2739705A1 true CA2739705A1 (en) 2010-05-06

Family

ID=41694413

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2739705A Abandoned CA2739705A1 (en) 2008-10-30 2009-10-29 Efficient expression of truncated human rnaset2 in e. coli

Country Status (8)

Country Link
US (1) US20110207667A1 (enExample)
EP (1) EP2346993A1 (enExample)
JP (1) JP2012507278A (enExample)
AU (1) AU2009309277A1 (enExample)
CA (1) CA2739705A1 (enExample)
EA (1) EA201100610A1 (enExample)
WO (1) WO2010049933A1 (enExample)
ZA (1) ZA201102615B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2863108A1 (en) * 2012-02-29 2013-09-06 F. Hoffmann-La Roche Ag Method for reduction of 1->3 reading frame shifts
EP3004339B1 (en) * 2013-05-29 2021-07-07 Cellectis New compact scaffold of cas9 in the type ii crispr system
US20160340659A1 (en) 2014-01-30 2016-11-24 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same
KR20240095481A (ko) * 2016-03-17 2024-06-25 세다르스-신나이 메디칼 센터 Rnaset2를 통한 염증성 장 질환의 진단 방법
WO2020112890A1 (en) 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60044977D1 (de) * 1999-09-24 2010-10-28 Ambion Inc Cocktail von nukleaseinhibitoren
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
ES2524601T3 (es) * 2004-09-29 2014-12-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. RNasa T2 humana recombinante y usos de la misma
US7608413B1 (en) * 2005-03-25 2009-10-27 Celera Corporation Kidney disease targets and uses thereof

Also Published As

Publication number Publication date
JP2012507278A (ja) 2012-03-29
ZA201102615B (en) 2012-03-28
AU2009309277A1 (en) 2010-05-06
EP2346993A1 (en) 2011-07-27
WO2010049933A1 (en) 2010-05-06
AU2009309277A8 (en) 2011-05-12
US20110207667A1 (en) 2011-08-25
EA201100610A1 (ru) 2011-10-31

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20141022

FZDE Discontinued

Effective date: 20161031