CA2737453A1 - Combination gas vaccines and therapeutics - Google Patents

Combination gas vaccines and therapeutics Download PDF

Info

Publication number
CA2737453A1
CA2737453A1 CA2737453A CA2737453A CA2737453A1 CA 2737453 A1 CA2737453 A1 CA 2737453A1 CA 2737453 A CA2737453 A CA 2737453A CA 2737453 A CA2737453 A CA 2737453A CA 2737453 A1 CA2737453 A1 CA 2737453A1
Authority
CA
Canada
Prior art keywords
spy0167
spy0416
mutant
protein
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2737453A
Other languages
English (en)
French (fr)
Inventor
Andrea Manetti
Sabrina Capo
Giuliano Bensi
Guido Grandi
Imma Margarit Y Ros
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2737453A1 publication Critical patent/CA2737453A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2737453A 2008-09-17 2009-09-17 Combination gas vaccines and therapeutics Abandoned CA2737453A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9755108P 2008-09-17 2008-09-17
US61/097,551 2008-09-17
PCT/IB2009/006949 WO2010076618A1 (en) 2008-09-17 2009-09-17 Combination gas vaccines and therapeutics

Publications (1)

Publication Number Publication Date
CA2737453A1 true CA2737453A1 (en) 2010-07-08

Family

ID=41508998

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2737453A Abandoned CA2737453A1 (en) 2008-09-17 2009-09-17 Combination gas vaccines and therapeutics

Country Status (18)

Country Link
US (2) US20100136041A1 (https=)
EP (1) EP2344523B1 (https=)
JP (2) JP5680536B2 (https=)
CN (1) CN102356090B (https=)
AU (1) AU2009334428B2 (https=)
BR (1) BRPI0919236A8 (https=)
CA (1) CA2737453A1 (https=)
DK (1) DK2344523T3 (https=)
ES (1) ES2566740T3 (https=)
HR (1) HRP20160306T1 (https=)
HU (1) HUE027618T2 (https=)
MX (1) MX2011002760A (https=)
NZ (1) NZ591633A (https=)
PL (1) PL2344523T3 (https=)
SI (1) SI2344523T1 (https=)
SM (1) SMT201600125B (https=)
WO (1) WO2010076618A1 (https=)
ZA (1) ZA201102005B (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0210128D0 (en) * 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
HUE034251T2 (en) * 2009-10-30 2018-02-28 Glaxosmithkline Biologicals Sa Purification of staphylococcus aureus type 5 and type 8 capsular saccharides
CN103239734B (zh) * 2012-02-10 2016-02-24 北京艾棣维欣生物技术有限公司 用于预防和/或治疗呼吸道合胞病毒感染的疫苗
GB201206366D0 (en) * 2012-04-11 2012-05-23 Absynth Biologics Ltd Bacterial vaccine
JP6283674B2 (ja) * 2012-09-18 2018-02-21 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム 外膜小胞
KR102730367B1 (ko) * 2014-04-15 2024-11-15 그리피스 유니버시티 그룹 a 스트렙토코쿠스 백신
BE1022553A1 (fr) * 2014-05-07 2016-05-31 Glaxosmithkline Biologicals Sa Mutants de spy0269
US10329601B2 (en) * 2015-12-28 2019-06-25 Ionian Technologies, Inc. Nicking and extension amplification reaction (NEAR) of Streptococcus species
CN112442472B (zh) * 2020-11-30 2023-05-26 四川大学华西医院 抗艰难梭菌的重组乳酸乳球菌、活载体疫苗及其制备方法
JP7601913B2 (ja) * 2021-01-19 2024-12-17 デンカ株式会社 タンパク質、溶血性連鎖球菌ワクチン、ｄｎａ、ベクター、形質転換体、タンパク質を製造する方法、バキュロウイルス、アグロバクテリウム、ラテックス粒子、キット及び抗ストレプトリジンｏ抗体の測定方法
GB202215414D0 (en) 2022-10-18 2022-11-30 Glaxosmithkline Biologicals Sa Vaccine
CN116875520B (zh) * 2023-07-12 2024-06-14 吉林农业大学 表达核糖体失活蛋白的乳酸菌及其在抗轮状病毒中的应用
CN120005039B (zh) * 2025-01-10 2025-12-19 遵义医科大学珠海校区 HtsA-SLOdm融合蛋白及其在制备A族链球菌疫苗中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8827038D0 (en) * 1988-11-18 1988-12-21 Kehoe M Streptolysin o antigens & uses
US5866135A (en) * 1994-04-21 1999-02-02 North American Vaccine, Inc. Group A streptococcal polysaccharide immunogenic compositions and methods
ES2505695T3 (es) * 2003-07-31 2014-10-10 Novartis Vaccines And Diagnostics, Inc. Composiciones inmunógenas para Streptococcus pyogenes
US7838010B2 (en) * 2004-10-08 2010-11-23 Novartis Vaccines And Diagnostics S.R.L. Immunogenic and therapeutic compositions for Streptococcus pyogenes
CA2668018A1 (en) * 2006-10-30 2008-09-12 Novartis Ag Immunogenic and therapeutic compositions for streptococcus pyogenes
KR101621837B1 (ko) * 2007-09-12 2016-05-17 노파르티스 아게 Ｇａｓ57 돌연변이 항원 및 ｇａｓ57 항체
EP2537857B1 (en) * 2007-12-21 2017-01-18 GlaxoSmithKline Biologicals SA Mutant forms of streptolysin O

Also Published As

Publication number Publication date
CN102356090B (zh) 2016-01-20
JP5680536B2 (ja) 2015-03-04
AU2009334428A1 (en) 2010-07-08
HRP20160306T1 (hr) 2016-04-22
EP2344523B1 (en) 2016-02-10
SI2344523T1 (sl) 2016-06-30
BRPI0919236A2 (pt) 2015-12-15
SMT201600125B (it) 2016-07-01
NZ591633A (en) 2012-10-26
US20100136041A1 (en) 2010-06-03
WO2010076618A1 (en) 2010-07-08
BRPI0919236A8 (pt) 2023-01-31
MX2011002760A (es) 2011-06-16
JP2012502969A (ja) 2012-02-02
AU2009334428B2 (en) 2014-02-20
JP2015038156A (ja) 2015-02-26
HUE027618T2 (en) 2016-11-28
DK2344523T3 (da) 2016-04-18
PL2344523T3 (pl) 2016-09-30
CN102356090A (zh) 2012-02-15
US20150132337A1 (en) 2015-05-14
ZA201102005B (en) 2016-09-28
EP2344523A1 (en) 2011-07-20
ES2566740T3 (es) 2016-04-15

Similar Documents

Publication Publication Date Title
AU2009334428B2 (en) Combination gas vaccines and therapeutics
US7731978B2 (en) Mutant forms of streptolysin O
US9102741B2 (en) GAS57 mutant antigens and GAS57 antibodies
WO2008108830A2 (en) Immunogenic and therapeutic compositions for streptococcus pyogenes
AU2013203022B2 (en) GAS57 mutant antigens and GAS57 antibodies
AU2013203063A1 (en) Combination gas vaccines and therapeutics

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140911

FZDE Discontinued

Effective date: 20190501