CA2732040A1 - Systems and methods for optical measurement of analyte concentration - Google Patents
Systems and methods for optical measurement of analyte concentration Download PDFInfo
- Publication number
- CA2732040A1 CA2732040A1 CA2732040A CA2732040A CA2732040A1 CA 2732040 A1 CA2732040 A1 CA 2732040A1 CA 2732040 A CA2732040 A CA 2732040A CA 2732040 A CA2732040 A CA 2732040A CA 2732040 A1 CA2732040 A1 CA 2732040A1
- Authority
- CA
- Canada
- Prior art keywords
- sensor
- waveform
- analyte
- indicator
- microcontroller
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000012491 analyte Substances 0.000 title claims abstract description 81
- 238000000034 method Methods 0.000 title claims abstract description 40
- 230000003287 optical effect Effects 0.000 title claims description 26
- 238000005259 measurement Methods 0.000 title claims description 22
- 230000005855 radiation Effects 0.000 claims abstract description 44
- 230000004044 response Effects 0.000 claims abstract description 21
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 31
- 239000001301 oxygen Substances 0.000 claims description 31
- 229910052760 oxygen Inorganic materials 0.000 claims description 31
- 230000000737 periodic effect Effects 0.000 claims description 19
- 230000005284 excitation Effects 0.000 claims description 14
- 238000004891 communication Methods 0.000 claims description 13
- MOBZIKDAUJCZDU-UHFFFAOYSA-L 4,7-diphenyl-1,10-phenanthroline;ruthenium(2+);diperchlorate Chemical compound [Ru+2].[O-]Cl(=O)(=O)=O.[O-]Cl(=O)(=O)=O.C1=CC=CC=C1C1=CC=NC2=C1C=CC1=C(C=3C=CC=CC=3)C=CN=C21.C1=CC=CC=C1C1=CC=NC2=C1C=CC1=C(C=3C=CC=CC=3)C=CN=C21.C1=CC=CC=C1C1=CC=NC2=C1C=CC1=C(C=3C=CC=CC=3)C=CN=C21 MOBZIKDAUJCZDU-UHFFFAOYSA-L 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000008280 blood Substances 0.000 claims description 5
- 210000004369 blood Anatomy 0.000 claims description 5
- 230000008859 change Effects 0.000 claims description 5
- 229910052747 lanthanoid Inorganic materials 0.000 claims description 5
- 150000002602 lanthanoids Chemical class 0.000 claims description 5
- 238000012546 transfer Methods 0.000 claims description 5
- 239000003570 air Substances 0.000 claims description 3
- 238000013480 data collection Methods 0.000 claims description 3
- 230000001419 dependent effect Effects 0.000 claims description 3
- 230000001678 irradiating effect Effects 0.000 claims description 3
- 238000010791 quenching Methods 0.000 claims description 3
- 230000000171 quenching effect Effects 0.000 claims description 3
- 229910052693 Europium Inorganic materials 0.000 claims description 2
- 150000001217 Terbium Chemical class 0.000 claims description 2
- 150000004945 aromatic hydrocarbons Chemical class 0.000 claims description 2
- OGPBJKLSAFTDLK-UHFFFAOYSA-N europium atom Chemical compound [Eu] OGPBJKLSAFTDLK-UHFFFAOYSA-N 0.000 claims description 2
- 230000006870 function Effects 0.000 description 20
- 238000005424 photoluminescence Methods 0.000 description 15
- 238000004020 luminiscence type Methods 0.000 description 8
- 241000894006 Bacteria Species 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 230000008901 benefit Effects 0.000 description 4
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 238000012544 monitoring process Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 239000002351 wastewater Substances 0.000 description 4
- 239000003990 capacitor Substances 0.000 description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 description 3
- 230000007613 environmental effect Effects 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000010865 sewage Substances 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 108700012359 toxins Proteins 0.000 description 3
- 238000005842 biochemical reaction Methods 0.000 description 2
- 239000001569 carbon dioxide Substances 0.000 description 2
- UBAZGMLMVVQSCD-UHFFFAOYSA-N carbon dioxide;molecular oxygen Chemical compound O=O.O=C=O UBAZGMLMVVQSCD-UHFFFAOYSA-N 0.000 description 2
- 238000002485 combustion reaction Methods 0.000 description 2
- 230000003111 delayed effect Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000000695 excitation spectrum Methods 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000002352 surface water Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 230000026683 transduction Effects 0.000 description 2
- 238000010361 transduction Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 206010011906 Death Diseases 0.000 description 1
- 238000004378 air conditioning Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 238000012993 chemical processing Methods 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000012937 correction Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000009189 diving Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000005281 excited state Effects 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 210000003608 fece Anatomy 0.000 description 1
- 239000003269 fluorescent indicator Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 239000010842 industrial wastewater Substances 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 150000002605 large molecules Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 230000005055 memory storage Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- VUZPPFZMUPKLLV-UHFFFAOYSA-N methane;hydrate Chemical compound C.O VUZPPFZMUPKLLV-UHFFFAOYSA-N 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000007539 photo-oxidation reaction Methods 0.000 description 1
- 238000009372 pisciculture Methods 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000006335 response to radiation Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N21/643—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" non-biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/18—Water
- G01N33/1806—Biological oxygen demand [BOD] or chemical oxygen demand [COD]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N9/00—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity
- G01N9/24—Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity by observing the transmission of wave or particle radiation through the material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6432—Quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
- G01N2021/7786—Fluorescence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Optics & Photonics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Plasma & Fusion (AREA)
- Biodiversity & Conservation Biology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8410008P | 2008-07-28 | 2008-07-28 | |
| US61/084,100 | 2008-07-28 | ||
| PCT/US2009/051633 WO2010014505A1 (en) | 2008-07-28 | 2009-07-24 | Systems and methods for optical measurement of analyte concentration |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2732040A1 true CA2732040A1 (en) | 2010-02-04 |
Family
ID=41606942
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2732040A Abandoned CA2732040A1 (en) | 2008-07-28 | 2009-07-24 | Systems and methods for optical measurement of analyte concentration |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100024526A1 (zh) |
| EP (1) | EP2313761A4 (zh) |
| JP (1) | JP2011529577A (zh) |
| KR (1) | KR20110051213A (zh) |
| CN (1) | CN102132145A (zh) |
| AU (1) | AU2009276832A1 (zh) |
| BR (1) | BRPI0916428A2 (zh) |
| CA (1) | CA2732040A1 (zh) |
| MX (1) | MX2011001114A (zh) |
| WO (1) | WO2010014505A1 (zh) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103533884B (zh) | 2011-03-15 | 2016-06-01 | 传感技术股份有限公司 | 氧化敏感性材料的集成催化保护 |
| EP2721382B1 (en) * | 2011-05-18 | 2023-01-18 | Samuel Walker Inman | Irregular excitation of optical sensors |
| EP2795295B1 (en) | 2011-12-12 | 2017-10-11 | Step Ahead Innovations, Inc. | Water-quality monitoring system |
| KR101159215B1 (ko) * | 2011-12-22 | 2012-06-25 | 한국생산기술연구원 | 가스 온도 및 농도 동시 계측 광학장치 |
| CN103172630B (zh) * | 2011-12-22 | 2015-09-23 | 海洋王照明科技股份有限公司 | 含菲啰啉有机半导体材料及其制备方法和有机电致发光器件 |
| US9693714B2 (en) * | 2012-02-10 | 2017-07-04 | Senseonics, Incorporated | Digital ASIC sensor platform |
| US10327714B2 (en) | 2012-03-29 | 2019-06-25 | Senseonics, Incorporated | Analyte concentration alert function for analyte sensor system |
| US10111588B2 (en) | 2012-03-29 | 2018-10-30 | Senseonics, Incorporated | Analyte sensor transceiver configured to provide tactile, visual, and/or aural feedback |
| US9414775B2 (en) | 2012-03-29 | 2016-08-16 | Senseonics, Incorporated | Purification of glucose concentration signal in an implantable fluorescence based glucose sensor |
| EP2856254B1 (en) | 2012-05-29 | 2019-11-06 | Siemens Healthcare Diagnostics Inc. | Shutter assembly for a luminescence-based sample analyzer |
| GB2509338B (en) * | 2012-11-16 | 2017-09-27 | Essentra Packaging & Security Ltd | Moisture control label |
| EP2976033A4 (en) * | 2013-03-19 | 2016-12-14 | Surgisense Corp | APPARATUSES, SYSTEMS AND METHODS FOR DETERMINING THE OXYGENATION OF A FABRIC |
| WO2014152845A1 (en) * | 2013-03-20 | 2014-09-25 | Siemens Healthcare Diagnostics Inc. | Light and shutter for a sample analyzer |
| CN103196806A (zh) * | 2013-04-03 | 2013-07-10 | 中国科学院电工研究所 | 空气粒子浓度和荧光强度数据的实时监测系统和监测方法 |
| US9784686B2 (en) | 2013-06-19 | 2017-10-10 | Step Ahead Innovations, Inc. | Aquatic environment water parameter testing systems and methods |
| EP3019072B1 (en) * | 2013-07-09 | 2020-06-10 | Senseonics, Incorporated | Purification of glucose concentration signal in an implantable fluorescence based glucose sensor |
| US9963556B2 (en) | 2013-09-18 | 2018-05-08 | Senseonics, Incorporated | Critical point drying of hydrogels in analyte sensors |
| MY181662A (en) * | 2014-10-13 | 2020-12-31 | Mimos Berhad | A system and method to extract phase shift of a fluorescence signal |
| US10436761B2 (en) | 2015-05-05 | 2019-10-08 | Honeywell International Inc. | Gas identification by measuring stain development at multiple specific wavelength regions with narrow band optical sensors |
| CN109073457B (zh) * | 2016-03-09 | 2021-12-28 | Ysi公司 | 用于多参数水质测量的光学硝酸盐传感器补偿算法 |
| US10041923B1 (en) * | 2017-04-12 | 2018-08-07 | Swift Engineering, Inc. | Spectrophotometric system for measuring water quality |
| CN111051860A (zh) * | 2017-08-30 | 2020-04-21 | 松下知识产权经营株式会社 | 含水量检测装置 |
| WO2020047397A1 (en) | 2018-08-31 | 2020-03-05 | Lucid Scientific, Inc. | Measurement of a dynamic system |
| CN109142230A (zh) * | 2018-09-19 | 2019-01-04 | 东莞市缔网通讯科技有限公司 | 一种高频通讯导线拉拔液成分检测的方法 |
| US20200209162A1 (en) * | 2018-12-31 | 2020-07-02 | Marco De Angeli | Smart label architecture with organic leds |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4900933A (en) * | 1986-09-08 | 1990-02-13 | C. R. Bard, Inc. | Excitation and detection apparatus for remote sensor connected by optical fiber |
| US5012809A (en) * | 1986-10-10 | 1991-05-07 | Shulze John E | Fiber optic catheter system with fluorometric sensor and integral flexure compensation |
| CA2079987A1 (en) * | 1991-10-31 | 1993-05-01 | Colleen C. Nagel | Sensors and methods for sensing |
| US5593854A (en) * | 1994-02-16 | 1997-01-14 | Becton Dickinson And Company | Data analysis method for use with fluorescent bacterial sensors |
| US5517313A (en) * | 1995-02-21 | 1996-05-14 | Colvin, Jr.; Arthur E. | Fluorescent optical sensor |
| US7335164B2 (en) * | 1996-07-15 | 2008-02-26 | Ntc Technology, Inc. | Multiple function airway adapter |
| US6815211B1 (en) * | 1998-08-04 | 2004-11-09 | Ntc Technology | Oxygen monitoring methods and apparatus (I) |
| US6325978B1 (en) * | 1998-08-04 | 2001-12-04 | Ntc Technology Inc. | Oxygen monitoring and apparatus |
| US5818582A (en) * | 1996-09-19 | 1998-10-06 | Ciencia, Inc. | Apparatus and method for phase fluorometry |
| US6111248A (en) * | 1996-10-01 | 2000-08-29 | Texas Instruments Incorporated | Self-contained optical sensor system |
| JPH10132749A (ja) * | 1996-10-01 | 1998-05-22 | Texas Instr Inc <Ti> | 集積蛍光生化学センサ |
| US6207961B1 (en) * | 1996-10-15 | 2001-03-27 | American Research Corporation Of Virginia | Loss compensation using digital-signal processing in fiber-optic fluorescence sensors |
| AT409306B (de) * | 1997-10-03 | 2002-07-25 | Hoffmann La Roche | Optisch chemischer sensor |
| JP4625180B2 (ja) * | 1998-03-11 | 2011-02-02 | センサーズ・フォー・メディシン・アンド・サイエンス・インコーポレイテッド | 被分析物の蛍光ランタニドキレートによる検出 |
| US6749811B2 (en) * | 1998-04-28 | 2004-06-15 | The Johns Hopkins University | Molecularly imprinted polymer solution anion sensor |
| US6304766B1 (en) * | 1998-08-26 | 2001-10-16 | Sensors For Medicine And Science | Optical-based sensing devices, especially for in-situ sensing in humans |
| DE69938663D1 (de) * | 1998-08-26 | 2008-06-19 | Sensors For Medecine And Scien | Optisch basierte sensor-vorrichtungen |
| EP1217942A1 (en) * | 1999-09-24 | 2002-07-03 | Healthetech, Inc. | Physiological monitor and associated computation, display and communication unit |
| US6612306B1 (en) * | 1999-10-13 | 2003-09-02 | Healthetech, Inc. | Respiratory nitric oxide meter |
| US6563585B1 (en) * | 1999-11-24 | 2003-05-13 | University Of Maryland Biotechnology Institute | Ratiometric fluorometer |
| US6426505B1 (en) * | 2000-01-19 | 2002-07-30 | University Of Maryland Biotechnology Institute | Phase-modulation fluorometer and method for measuring nanosecond lifetimes using a lock-in amplifier |
| US6632402B2 (en) * | 2001-01-24 | 2003-10-14 | Ntc Technology Inc. | Oxygen monitoring apparatus |
| WO2002090951A1 (en) * | 2001-05-04 | 2002-11-14 | Sensors For Medicine And Science, Inc. | Electro-optical sensing device with reference channel |
| US6664111B2 (en) * | 2001-08-22 | 2003-12-16 | 3M Innovative Properties Company | Fluorescence based oxygen sensor systems |
| JP2005506536A (ja) * | 2001-10-16 | 2005-03-03 | ザ ジョンズ ホプキンズ ユニバーシティ | 分子的にインプリントされたポリマー溶液アニオンセンサ |
| TWI293363B (en) * | 2001-12-11 | 2008-02-11 | Sensors For Med & Science Inc | High performance fluorescent optical sensor |
| US6744034B2 (en) * | 2002-01-30 | 2004-06-01 | Texas Instruments Incorporated | Micro-electromechanical apparatus and method with position sensor compensation |
| US7041986B2 (en) * | 2002-03-14 | 2006-05-09 | University Of Maryland Baltimore County | Device for discrimination of fluorescence lifetimes and uses therefor |
| JP2005523717A (ja) * | 2002-05-01 | 2005-08-11 | マサチューセッツ インスティテュート オブ テクノロジー | 生化学的過程の迅速なスクリーニングおよび分析のための微小発酵槽 |
| GB0426822D0 (en) * | 2004-12-07 | 2005-01-12 | Precisense As | Sensor for detection of glucose |
| CA2609430A1 (en) * | 2005-06-02 | 2006-12-07 | Glaxo Group Limited | Inductively powered remote oxygen sensor |
| US20070031283A1 (en) * | 2005-06-23 | 2007-02-08 | Davis Charles Q | Assay cartridges and methods for point of care instruments |
-
2009
- 2009-07-24 US US12/508,727 patent/US20100024526A1/en not_active Abandoned
- 2009-07-24 JP JP2011521208A patent/JP2011529577A/ja active Pending
- 2009-07-24 BR BRPI0916428A patent/BRPI0916428A2/pt not_active IP Right Cessation
- 2009-07-24 EP EP09803413.5A patent/EP2313761A4/en not_active Withdrawn
- 2009-07-24 KR KR1020117004840A patent/KR20110051213A/ko not_active Application Discontinuation
- 2009-07-24 CN CN2009801329827A patent/CN102132145A/zh active Pending
- 2009-07-24 MX MX2011001114A patent/MX2011001114A/es active IP Right Grant
- 2009-07-24 WO PCT/US2009/051633 patent/WO2010014505A1/en active Application Filing
- 2009-07-24 CA CA2732040A patent/CA2732040A1/en not_active Abandoned
- 2009-07-24 AU AU2009276832A patent/AU2009276832A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2011001114A (es) | 2011-04-21 |
| JP2011529577A (ja) | 2011-12-08 |
| US20100024526A1 (en) | 2010-02-04 |
| CN102132145A (zh) | 2011-07-20 |
| EP2313761A1 (en) | 2011-04-27 |
| BRPI0916428A2 (pt) | 2016-02-16 |
| EP2313761A4 (en) | 2013-08-14 |
| WO2010014505A1 (en) | 2010-02-04 |
| KR20110051213A (ko) | 2011-05-17 |
| AU2009276832A1 (en) | 2010-02-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20100024526A1 (en) | Systems and methods for optical measurement of analyte concentration | |
| US6563585B1 (en) | Ratiometric fluorometer | |
| EP1756550B1 (en) | Method for extending the useful life of optical sensors | |
| JP2011529577A5 (zh) | ||
| US8462343B2 (en) | Wireless sensor system for environmental monitoring | |
| CN110542667B (zh) | 一种便携式快速水质检测仪及水质检测方法 | |
| CN107389643B (zh) | 一种基于双通道锁相放大技术的溶解氧测量方法及装置 | |
| Lehner et al. | LUMOS-A sensitive and reliable optode system for measuring dissolved oxygen in the nanomolar range | |
| US20080190172A1 (en) | Inductively Powered Remote Oxygen Sensor | |
| EP2635624B1 (en) | Optical sensor and sensing system for oxygen monitoring in fluids using molybdenum cluster phosphorescence | |
| JPH04502207A (ja) | エレクトロケミルミネセンス測定装置 | |
| KR20090045954A (ko) | 이식된 센서 처리 시스템 및 방법 | |
| CN207081660U (zh) | 一种基于双通道锁相放大技术的溶解氧测量装置 | |
| CN104619828B (zh) | 微生物的检查方法及其装置 | |
| US8852509B2 (en) | Electronic device for analyzing aqueous solutions | |
| CN204613108U (zh) | 一种高精度光学溶解氧测量装置 | |
| EP2110430B1 (en) | Measuring cell, analyser, process, and computer program product for measuring biochemical oxygen demand (bod) | |
| JP2003004635A (ja) | 蛍光式酸素濃度計 | |
| US20100207035A1 (en) | Fluorescence based sensors utilizing a mirrored cavity | |
| TW202004180A (zh) | 全光譜水質分析系統 | |
| TWM565796U (zh) | Full spectrum water quality analysis system | |
| Chodavarapu et al. | CMOS-based biosensor systems using integrated nanostructured recognition elements |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20150724 |
|
| FZDE | Discontinued |
Effective date: 20150724 |