CA2731496A1 - Pyrazolopyridine kinase inhibitors - Google Patents
Pyrazolopyridine kinase inhibitors Download PDFInfo
- Publication number
- CA2731496A1 CA2731496A1 CA2731496A CA2731496A CA2731496A1 CA 2731496 A1 CA2731496 A1 CA 2731496A1 CA 2731496 A CA2731496 A CA 2731496A CA 2731496 A CA2731496 A CA 2731496A CA 2731496 A1 CA2731496 A1 CA 2731496A1
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Landscapes
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- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
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| US8294108P | 2008-07-23 | 2008-07-23 | |
| US61/082,941 | 2008-07-23 | ||
| PCT/US2009/051423 WO2010011762A1 (en) | 2008-07-23 | 2009-07-22 | Pyrazolopyridine kinase inhibitors |
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| CA2731496A1 true CA2731496A1 (en) | 2010-01-28 |
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| CA2731496A Abandoned CA2731496A1 (en) | 2008-07-23 | 2009-07-22 | Pyrazolopyridine kinase inhibitors |
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| US (1) | US20120165368A1 (enExample) |
| EP (1) | EP2321318A1 (enExample) |
| JP (1) | JP5542287B2 (enExample) |
| CN (1) | CN102131808A (enExample) |
| AU (1) | AU2009274017A1 (enExample) |
| CA (1) | CA2731496A1 (enExample) |
| MX (1) | MX2011000834A (enExample) |
| WO (1) | WO2010011762A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8569337B2 (en) | 2008-07-23 | 2013-10-29 | Vertex Pharmaceuticals Incorporated | Tri-cyclic pyrazolopyridine kinase inhibitors |
| MX2011001319A (es) | 2008-08-06 | 2011-04-05 | Vertex Pharma | Inhibidores de aminopiridina cinasa. |
| GEP20207129B (en) | 2009-06-17 | 2020-07-10 | Vertex Pharma | Inhibitors of influenza viruses replication |
| EP2528917B1 (en) * | 2010-01-27 | 2016-10-19 | Vertex Pharmaceuticals Incorporated | Pyrazolopyridines useful for the treatment of autoimmune, inflammatory or (hyper)proliferative diseases |
| MX2012008642A (es) * | 2010-01-27 | 2012-11-23 | Vertex Pharma | Inhibidores de cinasas de pirazolopiridinas. |
| RU2013132681A (ru) | 2010-12-16 | 2015-01-27 | Вертекс Фармасьютикалз Инкорпорейтед | Ингибиторы репликации вирусов гриппа |
| UA118010C2 (uk) | 2011-08-01 | 2018-11-12 | Вертекс Фармасьютікалз Інкорпорейтед | Інгібітори реплікації вірусів грипу |
| HUE038820T2 (hu) | 2013-11-13 | 2018-11-28 | Vertex Pharma | Eljárás influenzavírusok replikációjának inhibitorai elõállítására |
| PT3068776T (pt) | 2013-11-13 | 2019-08-26 | Vertex Pharma | Inibidores da replicação de vírus da gripe |
| EP3294717B1 (en) | 2015-05-13 | 2020-07-29 | Vertex Pharmaceuticals Inc. | Methods of preparing inhibitors of influenza viruses replication |
| WO2016183120A1 (en) | 2015-05-13 | 2016-11-17 | Vertex Pharmaceuticals Incorporated | Inhibitors of influenza viruses replication |
| CN108794480A (zh) * | 2017-04-28 | 2018-11-13 | 天津药物研究院有限公司 | 吡咯并嘧啶类化合物、其制备方法和用途 |
| WO2020142557A1 (en) | 2018-12-31 | 2020-07-09 | Biomea Fusion, Llc | Irreversible inhibitors of menin-mll interaction |
| TW202043205A (zh) | 2018-12-31 | 2020-12-01 | 美商拜歐米富士恩有限公司 | Menin-mll相互作用之抑制劑 |
| JP7891524B2 (ja) | 2021-08-11 | 2026-07-16 | バイオメア フュージョン，インコーポレイテッド | 真性糖尿病に対するメニン－ｍｌｌ相互作用の共有結合性阻害剤 |
| MX2024002189A (es) | 2021-08-20 | 2024-06-11 | Biomea Fusion Inc | Forma cristalina de n-[4-[4-(4-morfolinil)-7h-pirrolo[2,3-d]pirimi din-6-il]fenil]-4-[[3(r)-[(1-oxo)-2-propen-1-il)amino]-1-piperidi nil]metil]-2-piridinacarboxamida, un inhibidor irreversible de menina-mll para el tratamiento del cancer. |
| WO2024155719A1 (en) | 2023-01-18 | 2024-07-25 | Biomea Fusion, Inc. | Crystalline forms of n-[4-[4-(4-morpholinyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl]phenyl]-4-[[3(r)-[(l-oxo-2-propen-l-yl)amino]-l-piperidinyl]methyl]-2- pyridinecarboxamide as a covalentinhibitor of menin-mll interaction |
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| US7186716B2 (en) * | 2002-08-12 | 2007-03-06 | Sugen, Inc. | 3-Pyrrol-pyridopyrazoles and 3-pyrrolyl-indazoles as novel kinase inhibitors |
| US7514448B2 (en) * | 2004-04-02 | 2009-04-07 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of rock and other protein kinases |
| AU2005309566A1 (en) * | 2004-11-22 | 2006-06-01 | Vertex Pharmaceuticals Incorporated | Bicyclic inhibitors or Rho kinase |
-
2009
- 2009-07-22 WO PCT/US2009/051423 patent/WO2010011762A1/en not_active Ceased
- 2009-07-22 CN CN2009801327342A patent/CN102131808A/zh active Pending
- 2009-07-22 CA CA2731496A patent/CA2731496A1/en not_active Abandoned
- 2009-07-22 MX MX2011000834A patent/MX2011000834A/es not_active Application Discontinuation
- 2009-07-22 EP EP09790732A patent/EP2321318A1/en not_active Withdrawn
- 2009-07-22 JP JP2011520170A patent/JP5542287B2/ja not_active Expired - Fee Related
- 2009-07-22 AU AU2009274017A patent/AU2009274017A1/en not_active Abandoned
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2011
- 2011-12-01 US US13/308,605 patent/US20120165368A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20120165368A1 (en) | 2012-06-28 |
| AU2009274017A1 (en) | 2010-01-28 |
| JP2011529063A (ja) | 2011-12-01 |
| JP5542287B2 (ja) | 2014-07-09 |
| WO2010011762A1 (en) | 2010-01-28 |
| CN102131808A (zh) | 2011-07-20 |
| EP2321318A1 (en) | 2011-05-18 |
| MX2011000834A (es) | 2011-04-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20140722 |