CA2723769A1 - Anhydrous and hydrate forms of crystalline 2-((2s, 3r, 4e, 6e, 1oe, 12 s)-13-(4-fluorophenoxy)-2,3, 12-(trihydroxytrideca-4, 6, 10-trien-8- ynyl)oxy) acetic acid - Google Patents

Anhydrous and hydrate forms of crystalline 2-((2s, 3r, 4e, 6e, 1oe, 12 s)-13-(4-fluorophenoxy)-2,3, 12-(trihydroxytrideca-4, 6, 10-trien-8- ynyl)oxy) acetic acid Download PDF

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Publication number
CA2723769A1
CA2723769A1 CA2723769A CA2723769A CA2723769A1 CA 2723769 A1 CA2723769 A1 CA 2723769A1 CA 2723769 A CA2723769 A CA 2723769A CA 2723769 A CA2723769 A CA 2723769A CA 2723769 A1 CA2723769 A1 CA 2723769A1
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Canada
Prior art keywords
disease
crystalline
inflammatory
acid
trien
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Abandoned
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CA2723769A
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English (en)
French (fr)
Inventor
Klaus Bartel
Danja Grossbach
William Guilford
Michael Sander
Gabriele Winter
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Bayer Pharma AG
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Bayer Schering Pharma AG
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Publication date
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Publication of CA2723769A1 publication Critical patent/CA2723769A1/en
Abandoned legal-status Critical Current

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Otolaryngology (AREA)
CA2723769A 2008-05-22 2008-05-22 Anhydrous and hydrate forms of crystalline 2-((2s, 3r, 4e, 6e, 1oe, 12 s)-13-(4-fluorophenoxy)-2,3, 12-(trihydroxytrideca-4, 6, 10-trien-8- ynyl)oxy) acetic acid Abandoned CA2723769A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2008/004100 WO2009140984A1 (en) 2008-05-22 2008-05-22 Anhydrous and hydrate forms of crystalline 2- ( (2s, 3r, 4e, 6e, 1oe, 12s) -13- (4-fluorophenoxy) -2,3, 12- (trihydroxytrideca-4, 6, 10-trien-8-ynyl) oxy) acetic acid

Publications (1)

Publication Number Publication Date
CA2723769A1 true CA2723769A1 (en) 2009-11-26

Family

ID=40275970

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2723769A Abandoned CA2723769A1 (en) 2008-05-22 2008-05-22 Anhydrous and hydrate forms of crystalline 2-((2s, 3r, 4e, 6e, 1oe, 12 s)-13-(4-fluorophenoxy)-2,3, 12-(trihydroxytrideca-4, 6, 10-trien-8- ynyl)oxy) acetic acid

Country Status (6)

Country Link
EP (1) EP2288414A1 (ko)
JP (1) JP2011520929A (ko)
KR (1) KR20110010755A (ko)
CN (1) CN102036714A (ko)
CA (1) CA2723769A1 (ko)
WO (1) WO2009140984A1 (ko)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6831186B2 (en) * 2001-11-06 2004-12-14 Schering Aktiengesellschft Lipoxin A4 analogs
TW200816991A (en) * 2006-08-23 2008-04-16 Bayer Schering Pharma Ag Treatment and prevention of intestinal fibrosis

Also Published As

Publication number Publication date
WO2009140984A1 (en) 2009-11-26
KR20110010755A (ko) 2011-02-07
CN102036714A (zh) 2011-04-27
EP2288414A1 (en) 2011-03-02
JP2011520929A (ja) 2011-07-21

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Effective date: 20140522