CA2718914C - Method and apparatus for increasing rotational amplitude of abrasive element on high-speed rotational atherectomy device - Google Patents
Method and apparatus for increasing rotational amplitude of abrasive element on high-speed rotational atherectomy device Download PDFInfo
- Publication number
- CA2718914C CA2718914C CA2718914A CA2718914A CA2718914C CA 2718914 C CA2718914 C CA 2718914C CA 2718914 A CA2718914 A CA 2718914A CA 2718914 A CA2718914 A CA 2718914A CA 2718914 C CA2718914 C CA 2718914C
- Authority
- CA
- Canada
- Prior art keywords
- drive shaft
- counterweight
- eccentric
- proximal
- distal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title description 19
- 210000001367 artery Anatomy 0.000 claims abstract description 22
- 208000031481 Pathologic Constriction Diseases 0.000 claims abstract description 14
- 230000036262 stenosis Effects 0.000 claims abstract description 12
- 208000037804 stenosis Diseases 0.000 claims abstract description 12
- 230000007246 mechanism Effects 0.000 claims description 10
- 238000000926 separation method Methods 0.000 abstract description 2
- 239000007787 solid Substances 0.000 description 21
- 210000001519 tissue Anatomy 0.000 description 16
- 239000000463 material Substances 0.000 description 15
- 230000002966 stenotic effect Effects 0.000 description 9
- 230000000284 resting effect Effects 0.000 description 7
- 230000003902 lesion Effects 0.000 description 6
- 208000037260 Atherosclerotic Plaque Diseases 0.000 description 5
- 239000003082 abrasive agent Substances 0.000 description 5
- 230000006378 damage Effects 0.000 description 5
- 238000002399 angioplasty Methods 0.000 description 4
- 229910003460 diamond Inorganic materials 0.000 description 4
- 239000010432 diamond Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 239000011230 binding agent Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 231100000241 scar Toxicity 0.000 description 2
- 238000004804 winding Methods 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 229910052580 B4C Inorganic materials 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- NRTOMJZYCJJWKI-UHFFFAOYSA-N Titanium nitride Chemical compound [Ti]#N NRTOMJZYCJJWKI-UHFFFAOYSA-N 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- INAHAJYZKVIDIZ-UHFFFAOYSA-N boron carbide Chemical compound B12B3B4C32B41 INAHAJYZKVIDIZ-UHFFFAOYSA-N 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 210000004351 coronary vessel Anatomy 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000002542 deteriorative effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 238000009713 electroplating Methods 0.000 description 1
- 210000003038 endothelium Anatomy 0.000 description 1
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- 239000000835 fiber Substances 0.000 description 1
- 239000005350 fused silica glass Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 208000037803 restenosis Diseases 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 238000010408 sweeping Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- UONOETXJSWQNOL-UHFFFAOYSA-N tungsten carbide Chemical compound [W+]#[C-] UONOETXJSWQNOL-UHFFFAOYSA-N 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for with a guide wire
- A61B2017/22042—Details of the tip of the guide wire
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B2017/320004—Surgical cutting instruments abrasive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/32—Surgical cutting instruments
- A61B17/3205—Excision instruments
- A61B17/3207—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions
- A61B17/320758—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven
- A61B2017/320766—Atherectomy devices working by cutting or abrading; Similar devices specially adapted for non-vascular obstructions with a rotating cutting instrument, e.g. motor driven eccentric
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4614508P | 2008-04-18 | 2008-04-18 | |
| US61/046,145 | 2008-04-18 | ||
| US12/405,765 | 2009-03-17 | ||
| US12/405,765 US8177801B2 (en) | 2008-04-18 | 2009-03-17 | Method and apparatus for increasing rotational amplitude of abrasive element on high-speed rotational atherectomy device |
| PCT/US2009/037763 WO2009145973A2 (en) | 2008-04-18 | 2009-03-20 | Method and apparatus for increasing rotational amplitude of abrasive element on high-speed rotational atherectomy device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2718914A1 CA2718914A1 (en) | 2009-12-03 |
| CA2718914C true CA2718914C (en) | 2016-06-14 |
Family
ID=41201758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2718914A Expired - Fee Related CA2718914C (en) | 2008-04-18 | 2009-03-20 | Method and apparatus for increasing rotational amplitude of abrasive element on high-speed rotational atherectomy device |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8177801B2 (enExample) |
| EP (2) | EP2276411B1 (enExample) |
| JP (1) | JP5435821B2 (enExample) |
| CN (1) | CN102223846B (enExample) |
| AU (1) | AU2009251702B2 (enExample) |
| CA (1) | CA2718914C (enExample) |
| ES (1) | ES2587720T3 (enExample) |
| WO (1) | WO2009145973A2 (enExample) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5636363B2 (ja) | 2008-06-13 | 2014-12-03 | ディージェイティー、 エルエルシー | 衝撃波バルーンカテーテル装置 |
| US10702293B2 (en) | 2008-06-13 | 2020-07-07 | Shockwave Medical, Inc. | Two-stage method for treating calcified lesions within the wall of a blood vessel |
| US9044618B2 (en) | 2008-11-05 | 2015-06-02 | Shockwave Medical, Inc. | Shockwave valvuloplasty catheter system |
| US9642673B2 (en) | 2012-06-27 | 2017-05-09 | Shockwave Medical, Inc. | Shock wave balloon catheter with multiple shock wave sources |
| AU2013300176B2 (en) | 2012-08-06 | 2017-08-17 | Shockwave Medical, Inc. | Low profile electrodes for an angioplasty shock wave catheter |
| JP2015524709A (ja) | 2012-08-08 | 2015-08-27 | ショックウェーブ メディカル， インコーポレイテッド | 複数のバルーンを伴う衝撃波弁形成 |
| US9522012B2 (en) | 2012-09-13 | 2016-12-20 | Shockwave Medical, Inc. | Shockwave catheter system with energy control |
| US9333000B2 (en) | 2012-09-13 | 2016-05-10 | Shockwave Medical, Inc. | Shockwave catheter system with energy control |
| US10517631B2 (en) | 2012-09-17 | 2019-12-31 | Cardiovascular Systems, Inc. | Rotational atherectomy device with a system of eccentric abrading heads |
| US9289230B2 (en) * | 2012-09-17 | 2016-03-22 | Cardiovascular Systems, Inc. | Rotational atherectomy device with a system of eccentric abrading heads |
| EP2967635B1 (en) | 2013-03-12 | 2017-06-28 | Boston Scientific Scimed, Inc. | Vibration and inertia enhanced atherectomy |
| US20150094749A1 (en) * | 2013-03-14 | 2015-04-02 | Cardiovascular Systems, Inc. | Devices, systems and methods for a piloting tip bushing for rotational atherectomy |
| US20150142028A1 (en) * | 2013-03-14 | 2015-05-21 | Cardiovascular Systems, Inc. | Devices, systems and methods for a piloting tip bushing for rotational atherectomy |
| US20140316447A1 (en) * | 2013-03-14 | 2014-10-23 | Cardiovascular Systems, Inc. | Devices, systems and methods for a piloting tip bushing for rotational atherectomy |
| US9936970B2 (en) | 2013-03-14 | 2018-04-10 | Cardiovascular Systems, Inc. | Devices, systems and methods for an oscillating crown drive for rotational atherectomy |
| US9750525B2 (en) | 2013-03-14 | 2017-09-05 | Cardiovascular Systems, Inc. | Devices, systems and methods for an oscillating crown drive for rotational atherectomy |
| US9468457B2 (en) | 2013-09-30 | 2016-10-18 | Cardiovascular Systems, Inc. | Atherectomy device with eccentric crown |
| USD766433S1 (en) | 2013-11-04 | 2016-09-13 | Cardiovascular Systems, Inc. | Eccentric crown |
| US9788853B2 (en) | 2014-01-15 | 2017-10-17 | Cardio Flow, Inc. | Atherectomy devices and methods |
| CN106456208B (zh) | 2014-03-12 | 2020-04-03 | 波士顿科学有限公司 | 注入润滑斑块切除导管 |
| HUE056458T2 (hu) | 2014-07-03 | 2022-02-28 | Taryag Medical Ltd | Fejlesztett atherectomiás készülék |
| US10702300B2 (en) * | 2014-07-18 | 2020-07-07 | Cardiovascular Systems, Inc. | Methods, devices and systems for slow rotation of drive shaft driven atherectomy systems |
| US10405878B2 (en) | 2014-07-25 | 2019-09-10 | Boston Scientific Scimed, Inc. | Rotatable medical device |
| WO2016089847A1 (en) | 2014-12-04 | 2016-06-09 | Boston Scientific Scimed, Inc. | Rotatable medical device |
| JP2017536944A (ja) * | 2014-12-11 | 2017-12-14 | カーディオバスキュラー システムズ， インコーポレイテッド | 回転式アテレクトミー切除用のパイロットチップブッシングのための装置、システムおよび方法 |
| JP6781703B2 (ja) * | 2014-12-30 | 2020-11-04 | バード・ペリフェラル・バスキュラー・インコーポレーテッド | 回転式アテローム切除術用システムのための研磨要素 |
| WO2017087195A1 (en) | 2015-11-18 | 2017-05-26 | Shockwave Medical, Inc. | Shock wave electrodes |
| MX2018011459A (es) | 2016-03-21 | 2019-03-28 | Cardivascular Systems | Dispositivo de aterectomia rotacional con un sistema de cabezales de desgaste excentricos. |
| US10639062B2 (en) | 2016-04-06 | 2020-05-05 | Cardio Flow, Inc. | Atherectomy devices and methods |
| EP4309608A3 (en) | 2016-10-06 | 2024-04-17 | Shockwave Medical, Inc. | Aortic leaflet repair using shock wave applicators |
| US10441312B2 (en) | 2017-02-23 | 2019-10-15 | Cardio Flow, Inc. | Atherectomy devices and methods |
| US11517346B2 (en) * | 2017-02-24 | 2022-12-06 | Cardiovascular Systems, Inc. | Gearless cannulated motor assembly and system for rotational atherectomy |
| US11690645B2 (en) | 2017-05-03 | 2023-07-04 | Medtronic Vascular, Inc. | Tissue-removing catheter |
| US11051842B2 (en) | 2017-05-03 | 2021-07-06 | Medtronic Vascular, Inc. | Tissue-removing catheter with guidewire isolation liner |
| US10966737B2 (en) | 2017-06-19 | 2021-04-06 | Shockwave Medical, Inc. | Device and method for generating forward directed shock waves |
| US10709462B2 (en) | 2017-11-17 | 2020-07-14 | Shockwave Medical, Inc. | Low profile electrodes for a shock wave catheter |
| US10463390B1 (en) | 2018-05-24 | 2019-11-05 | Cardio Flow, Inc. | Atherectomy devices and methods |
| US11147582B2 (en) * | 2018-06-14 | 2021-10-19 | Cardio Flow, Inc. | Atherectomy devices and methods |
| AU2019290401B2 (en) | 2018-06-21 | 2025-02-27 | Shockwave Medical, Inc. | System for treating occlusions in body lumens |
| EP4520279A1 (en) | 2018-08-07 | 2025-03-12 | Cardio Flow, Inc. | Atherectomy devices |
| US11730509B2 (en) * | 2018-10-08 | 2023-08-22 | Cardiovascular Systems, Inc. | Devices and methods for generating orbital motion in drive shafts for rotational medical devices |
| CN118697424A (zh) | 2018-11-16 | 2024-09-27 | 美敦力瓦斯科尔勒公司 | 组织去除导管 |
| US11819236B2 (en) | 2019-05-17 | 2023-11-21 | Medtronic Vascular, Inc. | Tissue-removing catheter |
| EP4034006A1 (en) | 2019-09-24 | 2022-08-03 | Shockwave Medical, Inc. | System for treating thrombus in body lumens |
| EP4034005B1 (en) | 2019-09-24 | 2024-12-18 | Shockwave Medical, Inc. | Lesion crossing shock wave catheter |
| AU2020354885A1 (en) | 2019-09-24 | 2022-04-07 | Shockwave Medical, Inc. | Low profile electrodes for a shock wave catheter |
| JP7042861B2 (ja) * | 2020-03-23 | 2022-03-28 | バード・ペリフェラル・バスキュラー・インコーポレーテッド | 回転式アテローム切除術用システムのための研磨要素 |
| US11992232B2 (en) | 2020-10-27 | 2024-05-28 | Shockwave Medical, Inc. | System for treating thrombus in body lumens |
| US11896248B2 (en) | 2021-08-05 | 2024-02-13 | Nextern Innovation, Llc | Systems, devices and methods for generating subsonic pressure waves in intravascular lithotripsy |
| US11801066B2 (en) | 2021-08-05 | 2023-10-31 | Nextern Innovation, Llc | Systems, devices and methods for selection of arc location within a lithoplasty balloon spark gap |
| US11877761B2 (en) | 2021-08-05 | 2024-01-23 | Nextern Innovation, Llc | Systems, devices and methods for monitoring voltage and current and controlling voltage of voltage pulse generators |
| US12089861B2 (en) | 2021-08-05 | 2024-09-17 | Nextern Innovation, Llc | Intravascular lithotripsy system and device |
| US11957369B2 (en) | 2021-08-05 | 2024-04-16 | Nextern Innovation, Llc | Intravascular lithotripsy systems and methods |
| US12023098B2 (en) | 2021-10-05 | 2024-07-02 | Shockwave Medical, Inc. | Lesion crossing shock wave catheter |
| US12290268B2 (en) | 2023-03-31 | 2025-05-06 | Shockwave Medical, Inc. | Shockwave catheters for treating rhinosinusitis |
| US12035932B1 (en) | 2023-04-21 | 2024-07-16 | Shockwave Medical, Inc. | Intravascular lithotripsy catheter with slotted emitter bands |
| US12004771B1 (en) | 2023-06-27 | 2024-06-11 | Cardio Flow, Inc. | Rotational atherectomy devices and methods |
| US12220141B2 (en) | 2023-06-29 | 2025-02-11 | Shockwave Medical, Inc. | Catheter system with independently controllable bubble and arc generation |
| US12426904B2 (en) | 2023-11-17 | 2025-09-30 | Shockwave Medical, Inc. | Intravascular lithotripsy catheter with oscillating impactor |
| US12402899B2 (en) | 2023-11-30 | 2025-09-02 | Shockwave Medical, Inc. | Systems, devices, and methods for generating shock waves in a forward direction |
| WO2025171173A1 (en) | 2024-02-08 | 2025-08-14 | IV-X Medical, LLC | Intravascular lithotripsy system |
| US12433620B2 (en) | 2024-02-23 | 2025-10-07 | Shockwave Medical, Inc. | Locus emitter shock wave catheter devices with increased longevity and higher sonic output |
| US12471939B2 (en) | 2024-03-05 | 2025-11-18 | Shockwave Medical, Inc. | Shock wave catheter with retractable enclosure |
| US12178458B1 (en) | 2024-05-16 | 2024-12-31 | Shockwave Medical, Inc. | Guidewireless shock wave catheters |
| US12453565B1 (en) | 2024-11-18 | 2025-10-28 | Shockwave Medical, Inc. | Shock wave catheters and methods of use thereof for treating, imaging, and characterizing body lumens |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4018576A (en) | 1971-11-04 | 1977-04-19 | Abrasive Technology, Inc. | Diamond abrasive tool |
| AU607692B2 (en) * | 1986-01-06 | 1991-03-14 | Boston Scientific Corporation Northwest Technology Center, Inc. | Transluminal microdissection device |
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| DE4012649C2 (de) * | 1990-04-20 | 1997-01-09 | Osypka Peter | Dilatationskatheter |
| US5312427A (en) | 1992-10-16 | 1994-05-17 | Shturman Cardiology Systems, Inc. | Device and method for directional rotational atherectomy |
| US5360432A (en) | 1992-10-16 | 1994-11-01 | Shturman Cardiology Systems, Inc. | Abrasive drive shaft device for directional rotational atherectomy |
| US5584843A (en) * | 1994-12-20 | 1996-12-17 | Boston Scientific Corporation | Shaped wire multi-burr rotational ablation device |
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| US6217595B1 (en) | 1996-11-18 | 2001-04-17 | Shturman Cardiology Systems, Inc. | Rotational atherectomy device |
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| US6132444A (en) | 1997-08-14 | 2000-10-17 | Shturman Cardiology Systems, Inc. | Eccentric drive shaft for atherectomy device and method for manufacture |
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| GB2426458A (en) * | 2005-05-26 | 2006-11-29 | Leonid Shturman | Atherectomy device |
| GB2426455A (en) * | 2005-05-26 | 2006-11-29 | Leonid Shturman | A rotational atherectomy device with supports on the drive shaft |
| GB2426456B (en) * | 2005-05-26 | 2010-10-27 | Leonid Shturman | Rotational device with eccentric abrasive element and method of use |
| US8597313B2 (en) * | 2007-06-11 | 2013-12-03 | Cardiovascular Systems, Inc. | Eccentric abrading head for high-speed rotational atherectomy devices |
| US8348965B2 (en) * | 2007-10-23 | 2013-01-08 | Cardiovascular Systems, Inc. | Rotational atherectomy device with counterweighting |
-
2009
- 2009-03-17 US US12/405,765 patent/US8177801B2/en active Active
- 2009-03-20 ES ES09755336.6T patent/ES2587720T3/es active Active
- 2009-03-20 CN CN200980113282.3A patent/CN102223846B/zh not_active Expired - Fee Related
- 2009-03-20 CA CA2718914A patent/CA2718914C/en not_active Expired - Fee Related
- 2009-03-20 AU AU2009251702A patent/AU2009251702B2/en not_active Ceased
- 2009-03-20 JP JP2011505064A patent/JP5435821B2/ja active Active
- 2009-03-20 EP EP09755336.6A patent/EP2276411B1/en not_active Not-in-force
- 2009-03-20 EP EP16171110.6A patent/EP3078337A1/en not_active Withdrawn
- 2009-03-20 WO PCT/US2009/037763 patent/WO2009145973A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2718914A1 (en) | 2009-12-03 |
| HK1158917A1 (en) | 2012-07-27 |
| WO2009145973A2 (en) | 2009-12-03 |
| EP2276411A2 (en) | 2011-01-26 |
| US20090264908A1 (en) | 2009-10-22 |
| ES2587720T3 (es) | 2016-10-26 |
| AU2009251702A1 (en) | 2009-12-03 |
| US8177801B2 (en) | 2012-05-15 |
| EP3078337A1 (en) | 2016-10-12 |
| JP5435821B2 (ja) | 2014-03-05 |
| CN102223846A (zh) | 2011-10-19 |
| EP2276411A4 (en) | 2013-12-04 |
| EP2276411B1 (en) | 2016-05-25 |
| AU2009251702B2 (en) | 2013-03-14 |
| WO2009145973A3 (en) | 2010-01-21 |
| JP2011518586A (ja) | 2011-06-30 |
| CN102223846B (zh) | 2014-05-28 |
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| EEER | Examination request |
Effective date: 20140310 |
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| MKLA | Lapsed |
Effective date: 20190320 |