CA2718718A1 - Methods, devices and compositions for adhering hydrated polymer implants to bone - Google Patents

Methods, devices and compositions for adhering hydrated polymer implants to bone Download PDF

Info

Publication number
CA2718718A1
CA2718718A1 CA2718718A CA2718718A CA2718718A1 CA 2718718 A1 CA2718718 A1 CA 2718718A1 CA 2718718 A CA2718718 A CA 2718718A CA 2718718 A CA2718718 A CA 2718718A CA 2718718 A1 CA2718718 A1 CA 2718718A1
Authority
CA
Canada
Prior art keywords
bone
implant
polymer
isocyanate
containing compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2718718A
Other languages
English (en)
French (fr)
Inventor
David Myung
Michael Jaasma
Lampros Kourtis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomimedica Inc
Original Assignee
Biomimedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomimedica Inc filed Critical Biomimedica Inc
Publication of CA2718718A1 publication Critical patent/CA2718718A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0094—Physical treatment, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/06—Use of macromolecular materials
    • A61L33/068—Use of macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Plasma & Fusion (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
CA2718718A 2008-03-21 2009-03-23 Methods, devices and compositions for adhering hydrated polymer implants to bone Abandoned CA2718718A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7030508P 2008-03-21 2008-03-21
US61/070,305 2008-03-21
PCT/US2009/037979 WO2009117737A2 (en) 2008-03-21 2009-03-23 Methods, devices and compositions for adhering hydrated polymer implants to bone

Publications (1)

Publication Number Publication Date
CA2718718A1 true CA2718718A1 (en) 2009-09-24

Family

ID=40873290

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2718718A Abandoned CA2718718A1 (en) 2008-03-21 2009-03-23 Methods, devices and compositions for adhering hydrated polymer implants to bone

Country Status (6)

Country Link
US (2) US20090240337A1 (OSRAM)
EP (1) EP2268331A2 (OSRAM)
JP (1) JP2011515162A (OSRAM)
AU (1) AU2009225416A1 (OSRAM)
CA (1) CA2718718A1 (OSRAM)
WO (1) WO2009117737A2 (OSRAM)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090088846A1 (en) 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
US20100010114A1 (en) * 2008-07-07 2010-01-14 David Myung Hydrophilic Interpenetrating Polymer Networks Derived From Hydrophobic Polymers
US20120209396A1 (en) 2008-07-07 2012-08-16 David Myung Orthopedic implants having gradient polymer alloys
JP5722773B2 (ja) 2008-08-05 2015-05-27 バイオミメディカ インコーポレイテッド ポリウレタングラフト化ヒドロゲル
US10258473B2 (en) * 2008-11-19 2019-04-16 Softjoint Corporation Device and method for restoring joints with artificial cartilage
JP5544719B2 (ja) * 2009-01-27 2014-07-09 三菱レイヨン株式会社 ゲルおよびその製造方法
US9277999B2 (en) 2009-02-27 2016-03-08 University of Pittsburgh—of the Commonwealth System of Higher Education Joint bioscaffolds
US9439685B2 (en) 2009-05-12 2016-09-13 Bullard Spine, Llc Multi-layer osteoinductive, osteogenic, and osteoconductive carrier
EP2482763A4 (en) * 2009-10-02 2013-02-27 Said G Osman BIOLOGICAL DIARTHROSIS
WO2012027678A1 (en) 2010-08-27 2012-03-01 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same
EP2465549A1 (en) * 2010-11-17 2012-06-20 Zimmer GmbH Porous metal structures made from polymer preforms
CA2823954A1 (en) * 2011-01-10 2012-07-19 Biomimedica, Inc. Orthopedic implants having gradient polymer alloys
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
WO2013028951A1 (en) * 2011-08-25 2013-02-28 Synthes Usa, Llc Peek or pmma transparent implant comprising an adhesive layer of an uncured polymer.
KR20140115294A (ko) 2011-10-03 2014-09-30 바이오미메디카, 인코포레이티드 순응성 재료들을 또 다른 표면으로 앵커링하기 위한 중합체성 접착제
EP3335673B1 (en) 2011-11-21 2025-07-30 Hyalex Orthopaedics, Inc. Systems for anchoring orthopaedic implants to bone
US9682035B2 (en) 2012-02-23 2017-06-20 The Board Of Trustees Of The Leland Stanford Junior University Injectable hydrogel system to modulate host response at bone implant interface
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
EP3119448B1 (en) 2014-03-21 2020-04-22 University of Pittsburgh- Of the Commonwealth System of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
KR102504497B1 (ko) 2014-09-07 2023-02-27 오씨오 리미티드 이방성 생체복합재료 물질, 이를 포함하는 의학적 이식물 및 이의 치료방법
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
CN107106210B (zh) 2014-12-26 2021-05-04 奥西奥有限公司 连续纤维增强的生物复合材料医用植入物
US20160331539A1 (en) * 2015-05-12 2016-11-17 Elwha Llc Modifiable implants
US11077228B2 (en) 2015-08-10 2021-08-03 Hyalex Orthopaedics, Inc. Interpenetrating polymer networks
WO2017155956A1 (en) * 2016-03-07 2017-09-14 Ossio Ltd Surface treated biocomposite material, medical implants comprising same and methods of treatment thereof
US11491264B2 (en) 2016-06-27 2022-11-08 Ossio Ltd. Fiber reinforced biocomposite medical implants with high mineral content
US20210113739A1 (en) * 2018-04-20 2021-04-22 President And Fellows Of Harvard College Topological adhesion of materials
US10869950B2 (en) 2018-07-17 2020-12-22 Hyalex Orthopaedics, Inc. Ionic polymer compositions
USD945620S1 (en) 2020-01-29 2022-03-08 Biopoly, Llc Great toe implant
US11801143B2 (en) 2021-07-01 2023-10-31 Hyalex Orthopaedics, Inc. Multi-layered biomimetic osteochondral implants and methods of using thereof
IL294542A (en) 2021-07-19 2023-02-01 Ossio Ltd A device with a tube for inserting implants with an adjustable insertion depth

Family Cites Families (107)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2914737C3 (de) * 1979-04-11 1981-12-10 Feldmühle AG, 4000 Düsseldorf Hüftkopf-Kappen-Endoprothese
US4320709A (en) * 1980-09-29 1982-03-23 Pyro-Sciences, Inc. Hazardous materials incineration system
US4439583A (en) * 1980-11-12 1984-03-27 Tyndale Plains-Hunter, Ltd. Polyurethane diacrylate compositions useful in forming canulae
US4502161A (en) * 1981-09-21 1985-03-05 Wall W H Prosthetic meniscus for the repair of joints
US4500676A (en) * 1983-12-15 1985-02-19 Biomatrix, Inc. Hyaluronate modified polymeric articles
US4575539A (en) * 1985-06-03 1986-03-11 E. R. Squibb & Sons, Inc. Drug delivery systems including novel interpenetrating polymer networks and method
US5114627A (en) * 1986-10-16 1992-05-19 Cbs Lens Method for producing a collagen hydrogel
US5112350A (en) * 1986-10-16 1992-05-12 Cbs Lens, A California General Partnership Method for locating on a cornea an artificial lens fabricated from a collagen-hydrogel for promoting epithelial cell growth and regeneration of the stroma
US5290548A (en) * 1987-04-10 1994-03-01 University Of Florida Surface modified ocular implants, surgical instruments, devices, prostheses, contact lenses and the like
US5100689A (en) * 1987-04-10 1992-03-31 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US5094876A (en) * 1987-04-10 1992-03-10 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
US5282851A (en) * 1987-07-07 1994-02-01 Jacob Labarre Jean Intraocular prostheses
US5087392A (en) * 1988-05-31 1992-02-11 Sola Usa, Inc. Method of mold contact lenses
US5115056A (en) * 1989-06-20 1992-05-19 Ciba-Geigy Corporation Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof
IE65208B1 (en) * 1990-01-25 1995-10-04 Howmedia Inc Bone cement
CA2101773A1 (en) * 1991-01-31 1992-08-01 Toyoichi Tanaka Interpenetrating-polymer network phase-transition gels
JP3007903B2 (ja) * 1991-03-29 2000-02-14 京セラ株式会社 人工椎間板
AU650156B2 (en) * 1992-08-05 1994-06-09 Lions Eye Institute Limited Keratoprosthesis and method of producing the same
BR9306848A (pt) * 1992-08-07 1998-12-08 Keravision Inc Anel polimérico dividido para introdução no estroma
US5556429A (en) * 1994-05-06 1996-09-17 Advanced Bio Surfaces, Inc. Joint resurfacing system
US5591170A (en) * 1994-10-14 1997-01-07 Genesis Orthopedics Intramedullary bone cutting saw
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
AU722250B2 (en) * 1995-11-15 2000-07-27 Seikagaku Corporation Photocured crosslinked-hyaluronic acid gel and method of preparation thereof
US6238799B1 (en) * 1996-02-09 2001-05-29 Surface Solutions Laboratories, Inc. Articles prepared from water-based hydrophilic coating compositions
US5817704A (en) * 1996-03-08 1998-10-06 The Procter & Gamble Company Heterogeneous foam materials
FR2749753B1 (fr) * 1996-06-14 1998-12-24 Mosseri Raphael Prothese totale de hanche destinee a etre posee par voie endo-articulaire et son dispositif ancillaire
KR19990077175A (ko) * 1996-11-13 1999-10-25 다나까 쿄이찌 인공각막
US5904927A (en) * 1997-03-14 1999-05-18 Northeastern University Drug delivery using pH-sensitive semi-interpenetrating network hydrogels
US6224893B1 (en) * 1997-04-11 2001-05-01 Massachusetts Institute Of Technology Semi-interpenetrating or interpenetrating polymer networks for drug delivery and tissue engineering
US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
US6053251A (en) * 1997-05-15 2000-04-25 Halliburton Energy Services, Inc. Reduced travel operating mechanism for downhole tools
US6221467B1 (en) * 1997-06-03 2001-04-24 Scimed Life Systems, Inc. Coating gradient for lubricious coatings on balloon catheters
AU758800B2 (en) * 1998-02-23 2003-03-27 Gkss-Forschungszentrum Geesthacht Gmbh Shape memory polymers
US7019192B2 (en) * 1998-02-27 2006-03-28 Musculoskeletal Transplant Foundation Composition for filling bone defects
US6057406A (en) * 1998-08-03 2000-05-02 The University Of Southern Mississippi Functionally gradient polymeric materials
US6361560B1 (en) * 1998-12-23 2002-03-26 Anamed, Inc. Corneal implant and method of manufacture
CA2358565A1 (en) * 1999-01-22 2000-07-27 Peter S. Dardi Medical adhesives
US6376742B1 (en) * 1999-02-17 2002-04-23 Richard J. Zdrahala In vivo tissue engineering with biodegradable polymers
US6239209B1 (en) * 1999-02-23 2001-05-29 Reichhold, Inc. Air curable water-borne urethane-acrylic hybrids
US6332887B1 (en) * 1999-04-06 2001-12-25 Benjamin D. Knox Spinal fusion instrumentation system
US6673079B1 (en) * 1999-08-16 2004-01-06 Washington University Device for lengthening and reshaping bone by distraction osteogenesis
US7008635B1 (en) * 1999-09-10 2006-03-07 Genzyme Corporation Hydrogels for orthopedic repair
US6264695B1 (en) * 1999-09-30 2001-07-24 Replication Medical, Inc. Spinal nucleus implant
US7547324B2 (en) * 2000-02-16 2009-06-16 Trans1, Inc. Spinal mobility preservation apparatus having an expandable membrane
US6626945B2 (en) * 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US6689165B2 (en) * 2000-03-31 2004-02-10 Board Of Supervisors Of Louisana State University And Agricultural And Mechanical College Surface modifications for enhanced epithelialization
US6846875B2 (en) * 2000-04-10 2005-01-25 Pharmacia Groningen Bv Hydrogels and methods for their production
US6372815B1 (en) * 2000-04-18 2002-04-16 Ocular Sciences Inc Ophthalmic lenses and compositions, and methods for producing same
US7163541B2 (en) * 2002-12-03 2007-01-16 Arthrosurface Incorporated Tibial resurfacing system
US6679917B2 (en) * 2000-05-01 2004-01-20 Arthrosurface, Incorporated System and method for joint resurface repair
EP2314257B9 (en) * 2000-05-01 2013-02-27 ArthroSurface, Inc. System for joint resurface repair
US7678151B2 (en) * 2000-05-01 2010-03-16 Ek Steven W System and method for joint resurface repair
JP2004510199A (ja) * 2000-09-28 2004-04-02 ノバルティス　アクチエンゲゼルシャフト 増加した涙流のための有孔レンズ及びそのレンズの製造方法
US6524327B1 (en) * 2000-09-29 2003-02-25 Praxis, Llc In-situ bonds
US7335205B2 (en) * 2001-03-02 2008-02-26 Woodwelding Ag Implants, device and method for joining tissue parts
AU2002258913A1 (en) * 2001-04-23 2002-11-05 Wisconsin Alumni Research Foundation Bifunctional-modified hydrogels
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US6747090B2 (en) * 2001-07-16 2004-06-08 Pharmacia Groningen Bv Compositions capable of forming hydrogels in the eye
DE10150737A1 (de) * 2001-10-15 2003-04-30 Hilti Ag Mehrkomponenten-Ortschaumsystem und dessen Verwendung
WO2003071339A1 (en) * 2002-02-15 2003-08-28 Zms, Llc Polymerization process and materials for biomedical applications
US6955716B2 (en) * 2002-03-01 2005-10-18 American Dental Association Foundation Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates
DE10217351B3 (de) * 2002-04-18 2004-02-12 Mnemoscience Gmbh Interpenetrierende Netzwerke
AU2002309026A1 (en) * 2002-05-01 2003-11-17 Hokkaido Technology Licensing Office Co., Ltd. Gel having multiple network structure and method for preparation thereof
US7235102B2 (en) * 2002-05-10 2007-06-26 Ferree Bret A Prosthetic components with contained compressible resilient members
US7476398B1 (en) * 2002-06-28 2009-01-13 Universite Laval Corneal implant and uses thereof
ES2309350T3 (es) * 2002-07-11 2008-12-16 Advanced Bio Surfaces, Inc. Metodo y equipo para artroplastia interposicional.
AU2003281815A1 (en) * 2002-08-02 2004-02-23 The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Hu Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same
US20040028804A1 (en) * 2002-08-07 2004-02-12 Anderson Daniel G. Production of polymeric microarrays
US7959636B2 (en) * 2002-08-15 2011-06-14 Arthrex, Inc. Osteochondral repair using plug fashioned from whole distal femur or condyle formed of hydrogel composition
US7264634B2 (en) * 2002-09-20 2007-09-04 Arthrex, Inc. Method and instrumentation for osteochondral repair using preformed implants
US8673333B2 (en) * 2002-09-25 2014-03-18 The Johns Hopkins University Cross-linked polymer matrices, and methods of making and using same
US7049351B2 (en) * 2002-11-01 2006-05-23 Novartis Ag Moldings and preparation and uses thereof
US6733533B1 (en) * 2002-11-19 2004-05-11 Zimmer Technology, Inc. Artificial spinal disc
WO2004055057A1 (en) * 2002-12-18 2004-07-01 The University Of Melbourne Hydrogel preparation and process of manufacture thereof
EP1592728A2 (en) * 2003-01-16 2005-11-09 Carnegie-Mellon University Biodegradable polyurethanes and use thereof
US7160305B2 (en) * 2003-03-07 2007-01-09 Arthrex, Inc. Retrodrill technique for insertion of autograft, allograft or synthetic osteochondral implants
US7758497B2 (en) * 2003-06-20 2010-07-20 Contura A/S Endoscopic attachment device
US7176247B1 (en) * 2003-06-27 2007-02-13 The United States Of America As Represented By The Secretary Of The Army Interpenetrating polymer network
US7582698B2 (en) * 2003-07-02 2009-09-01 Lubrizol Advanced Materials, Inc. Water dispersions of non-uniform polyurethane particles
WO2005014073A1 (en) * 2003-08-08 2005-02-17 Contura Sa Implantable hydrogel with resorbable shell for use as an endoprothesis
US10583220B2 (en) * 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
US7217294B2 (en) * 2003-08-20 2007-05-15 Histogenics Corp. Acellular matrix implants for treatment of articular cartilage, bone or osteochondral defects and injuries and method for use thereof
US7544381B2 (en) * 2003-09-09 2009-06-09 Boston Scientific Scimed, Inc. Lubricious coatings for medical device
US20050054774A1 (en) * 2003-09-09 2005-03-10 Scimed Life Systems, Inc. Lubricious coating
US20050113836A1 (en) * 2003-11-25 2005-05-26 Lozier Antony J. Expandable reamer
NZ549250A (en) * 2004-02-20 2009-12-24 Woodwelding Ag An implant for bone tissue using a stepped profile and a liquefiable material to connect the implant to the bone
US20070100457A1 (en) * 2004-03-04 2007-05-03 Hyde Edward R Jr Paramagnetic liquid interface
EP1779875A4 (en) * 2004-06-18 2011-08-24 Univ Hokkaido Nat Univ Corp ARTIFICIAL SEMILUNAR CARTLE
EP1611877A1 (en) * 2004-06-28 2006-01-04 Universidade de Coimbra Method for preparing sustained-release therapeutic ophthalmic articles using compressed fluids for impregnation of drugs
EP1627615A3 (en) * 2004-08-18 2006-11-02 Arthrex, Inc. Modular joint replacement implant with hydrogel surface
US7857849B2 (en) * 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior Iniversity Artificial corneal implant
US20090088846A1 (en) * 2007-04-17 2009-04-02 David Myung Hydrogel arthroplasty device
TW200640061A (en) * 2005-01-04 2006-11-16 Hitachi Chemical Co Ltd Phase separation type polymer electrolyte film, electrode/phase separation type polymer electrolyte film assembly employing the same, processes for producing the same, and fuel cell employing the same
US7547319B2 (en) * 2005-06-15 2009-06-16 Ouroboros Medical Mechanical apparatus and method for artificial disc replacement
US7651701B2 (en) * 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
DE102005042381A1 (de) * 2005-09-06 2007-03-08 Herbert Kannegiesser Gmbh Verfahren und Vorrichtung zum Waschen und/oder Schleudern von Wäsche
US8420605B2 (en) * 2005-09-07 2013-04-16 The University Of Strathclyde Hydrogel compositions
US20070088444A1 (en) * 2005-10-13 2007-04-19 Robert A Hodorek Method for repairing a bone defect using a formable implant which hardens in vivo
WO2007062079A2 (en) * 2005-11-21 2007-05-31 Philipp Lang Devices and methods for treating facet joints, uncovertebral joints, costovertebral joints and other joints
JP2009518135A (ja) * 2005-12-07 2009-05-07 ズィマー・インコーポレーテッド 照射を使用してハイドロゲルを結合させるまたは改質する方法
US8110242B2 (en) * 2006-03-24 2012-02-07 Zimmer, Inc. Methods of preparing hydrogel coatings
US20080058954A1 (en) * 2006-08-22 2008-03-06 Hai Trieu Methods of treating spinal injuries using injectable flowable compositions comprising organic materials
US7731988B2 (en) * 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
WO2009032071A2 (en) * 2007-08-29 2009-03-12 Spinemedica Corporation Orthopaedic cement mixtures with low weight percent polyvinyl alcohol (pva) solution
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US20100056646A1 (en) * 2008-03-12 2010-03-04 Shalaby Shalaby W Hydroswellable, segmented, aliphatic polyurethane ureas and intra-articular devices therefrom
WO2012027678A1 (en) * 2010-08-27 2012-03-01 Biomimedica, Inc. Hydrophobic and hydrophilic interpenetrating polymer networks derived from hydrophobic polymers and methods of preparing the same

Also Published As

Publication number Publication date
AU2009225416A1 (en) 2009-09-24
WO2009117737A3 (en) 2010-11-04
WO2009117737A2 (en) 2009-09-24
US20120277807A1 (en) 2012-11-01
EP2268331A2 (en) 2011-01-05
JP2011515162A (ja) 2011-05-19
US20090240337A1 (en) 2009-09-24

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