CA2716546A1 - Sugar glassified virus like particles (vlps) - Google Patents
Sugar glassified virus like particles (vlps) Download PDFInfo
- Publication number
- CA2716546A1 CA2716546A1 CA2716546A CA2716546A CA2716546A1 CA 2716546 A1 CA2716546 A1 CA 2716546A1 CA 2716546 A CA2716546 A CA 2716546A CA 2716546 A CA2716546 A CA 2716546A CA 2716546 A1 CA2716546 A1 CA 2716546A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- vlp
- powder
- sugar glass
- sugar
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16023—Virus like particles [VLP]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
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- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3124308P | 2008-02-25 | 2008-02-25 | |
| US61/031,243 | 2008-02-25 | ||
| PCT/US2009/035122 WO2009108689A1 (en) | 2008-02-25 | 2009-02-25 | Sugar glassified virus like particles (vlps) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2716546A1 true CA2716546A1 (en) | 2009-09-03 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2716546A Abandoned CA2716546A1 (en) | 2008-02-25 | 2009-02-25 | Sugar glassified virus like particles (vlps) |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP2254554A1 (enExample) |
| JP (1) | JP2011514337A (enExample) |
| CN (1) | CN102014873A (enExample) |
| BR (1) | BRPI0908861A2 (enExample) |
| CA (1) | CA2716546A1 (enExample) |
| MX (1) | MX2010009351A (enExample) |
| RU (1) | RU2010139478A (enExample) |
| WO (1) | WO2009108689A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3067064T3 (pl) | 2008-12-09 | 2020-11-02 | Novavax, Inc. | Zmodyfikowane białka f rsv i sposoby ich wykorzystania |
| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| US20130028933A1 (en) * | 2009-12-28 | 2013-01-31 | Ligocyte Pharmaceuticals, Inc. | Methods for stabilizing influenza antigen enveloped virus-based virus-like particle solutions |
| GB201002419D0 (en) * | 2010-02-12 | 2010-03-31 | Isis Innovation | Stable live vaccine formulations |
| EA201390810A1 (ru) | 2010-12-02 | 2013-09-30 | Онколитикс Байотек Инк. | Жидкие вирусные составы |
| ES2630012T3 (es) * | 2010-12-02 | 2017-08-17 | Oncolytics Biotech Inc. | Formulaciones virales liofilizadas |
| WO2012177970A1 (en) | 2011-06-24 | 2012-12-27 | Merck Sharp & Dohme Corp. | Hpv vaccine formulations comprising aluminum adjuvant and methods of producing same |
| CA2849471A1 (en) * | 2011-09-30 | 2013-04-04 | Novavax, Inc. | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
| US20130089638A1 (en) * | 2011-10-11 | 2013-04-11 | Mead Johnson Nutrition Company | Compositions Comprising Maltotriose And Methods Of Using Same To Inhibit Damage Caused By Dehydration Processes |
| CN105579059B (zh) | 2013-09-03 | 2020-07-31 | 佐治亚科技研究公司 | 热稳定的疫苗配制物、工艺和包含疫苗配制物的微针 |
| EP3763383A1 (en) * | 2013-12-16 | 2021-01-13 | Massachusetts Institute Of Technology | Micromolded or 3-d printed pulsatile release vaccine formulations |
| MX2016007786A (es) | 2013-12-16 | 2017-03-03 | Massachusetts Inst Technology | Formulaciones de sal de micronutrientes fortificadas. |
| IL310015B1 (en) * | 2013-12-31 | 2025-10-01 | Access To Advanced Health Inst | Single vial formulation |
| US11273127B2 (en) | 2014-05-06 | 2022-03-15 | The Regents Of The University Of Colorado, A Body Corporate | Compositions, methods and uses for thermally stable multi-targeted antigens |
| WO2015171810A1 (en) * | 2014-05-06 | 2015-11-12 | The Regents Of The University Of Colorado, A Body Corporate | Compositions, methods and uses for thermally stable human papillomavirus formulations |
| US10426829B2 (en) | 2015-09-03 | 2019-10-01 | Novavax, Inc. | Vaccine compositions having improved stability and immunogenicity |
| KR20180041237A (ko) * | 2015-09-04 | 2018-04-23 | 인벤트프라이즈 엘엘씨 | Vlp 안정화된 백신 조성물 |
| ES3028362T3 (en) | 2017-07-24 | 2025-06-19 | Novavax Inc | Methods and compositions for treating respiratory disease |
| CA3092984A1 (en) | 2018-03-19 | 2019-09-26 | Novavax, Inc. | Multivalent influenza nanoparticle vaccines |
| CN114340665A (zh) * | 2019-05-25 | 2022-04-12 | 传染病研究所 | 用于对佐剂疫苗乳剂进行喷雾干燥的组合物和方法 |
| CN115835856A (zh) | 2020-05-13 | 2023-03-21 | 麻省理工学院 | 聚合物微装置的组合物以及其在癌症免疫疗法中的用途 |
| CN115350281A (zh) * | 2022-09-20 | 2022-11-18 | 华派生物工程集团有限公司 | 一种病毒样颗粒疫苗冻干保护剂及其制备方法 |
| WO2025058011A1 (ja) * | 2023-09-13 | 2025-03-20 | 国立大学法人大阪大学 | 経鼻投与用組成物 |
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| US6290991B1 (en) * | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
| GB9705588D0 (en) * | 1997-03-18 | 1997-05-07 | Anglia Research Foundation | Stable particle in liquid formulations |
| KR20120066688A (ko) * | 2003-02-24 | 2012-06-22 | 파마슈티칼 프로덕션스, 인크. | 경점막 약물 전달 시스템 |
| GB0409795D0 (en) * | 2004-04-30 | 2004-06-09 | Glaxosmithkline Biolog Sa | Drying method |
| US7871632B2 (en) * | 2004-07-12 | 2011-01-18 | Adventrx Pharmaceuticals, Inc. | Compositions for delivering highly water soluble drugs |
| GB0502661D0 (en) * | 2005-02-09 | 2005-03-16 | Stabilitech Ltd | A desiccated product |
| MY139088A (en) * | 2005-02-21 | 2009-08-28 | Lg Life Sciences Ltd | Sustained release composition of protein drug |
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- 2009-02-25 MX MX2010009351A patent/MX2010009351A/es unknown
- 2009-02-25 RU RU2010139478/15A patent/RU2010139478A/ru not_active Application Discontinuation
- 2009-02-25 JP JP2010547860A patent/JP2011514337A/ja active Pending
- 2009-02-25 BR BRPI0908861A patent/BRPI0908861A2/pt not_active IP Right Cessation
- 2009-02-25 EP EP09713904A patent/EP2254554A1/en not_active Withdrawn
- 2009-02-25 CN CN2009801146099A patent/CN102014873A/zh active Pending
- 2009-02-25 WO PCT/US2009/035122 patent/WO2009108689A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CN102014873A (zh) | 2011-04-13 |
| EP2254554A1 (en) | 2010-12-01 |
| BRPI0908861A2 (pt) | 2018-02-06 |
| RU2010139478A (ru) | 2012-05-20 |
| JP2011514337A (ja) | 2011-05-06 |
| MX2010009351A (es) | 2011-03-04 |
| WO2009108689A1 (en) | 2009-09-03 |
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