CA2713755A1 - Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein - Google Patents
Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein Download PDFInfo
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- CA2713755A1 CA2713755A1 CA2713755A CA2713755A CA2713755A1 CA 2713755 A1 CA2713755 A1 CA 2713755A1 CA 2713755 A CA2713755 A CA 2713755A CA 2713755 A CA2713755 A CA 2713755A CA 2713755 A1 CA2713755 A1 CA 2713755A1
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- A61K38/18—Growth factors; Growth regulators
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| US61/093,228 | 2008-08-29 | ||
| PCT/US2009/033275 WO2009100253A1 (en) | 2008-02-07 | 2009-02-05 | Rescue of photoreceptors by intravitreal administation of an expression vector encoding a therapeutic protein |
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| CA2713755A1 true CA2713755A1 (en) | 2009-08-13 |
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| CA2713755A Abandoned CA2713755A1 (en) | 2008-02-07 | 2009-02-05 | Rescue of photoreceptors by intravitreal administration of an expression vector encoding a therapeutic protein |
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| CN101980668A (zh) * | 2008-02-07 | 2011-02-23 | 赛拉基因公司 | 通过玻璃体内施用编码治疗用蛋白质的表达载体救援光感器 |
| GB201103062D0 (en) * | 2011-02-22 | 2011-04-06 | Isis Innovation | Method |
| CN107937341A (zh) * | 2011-02-25 | 2018-04-20 | 国立研究开发法人理化学研究所 | 视网膜色素上皮细胞片层的生产方法 |
| CN105120901A (zh) | 2012-07-11 | 2015-12-02 | 宾夕法尼亚大学托管会 | Rpgr x染色体连锁视网膜退化的aav介导的基因治疗 |
| US20160256571A1 (en) * | 2013-09-30 | 2016-09-08 | Sanofi | Invention |
| WO2015082690A1 (en) * | 2013-12-06 | 2015-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for expressing a polynucleotide of interest in the retinal pigment epithelium of a subject |
| WO2016164920A1 (en) * | 2015-04-09 | 2016-10-13 | Cornell University | Gene therapy to prevent reactions to allergens |
| CA3004807C (en) * | 2015-12-04 | 2022-02-22 | Universite Pierre Et Marie Curie (Paris 6) | Promoters and uses thereof |
| US20190269755A1 (en) * | 2016-04-29 | 2019-09-05 | Gensight Biologics Sa | Optogenetic visual restoration using chrimson |
| PL239642B1 (pl) * | 2018-08-16 | 2021-12-20 | Pomorski Univ Medyczny W Szczecinie | Kompozycja do doszklistkowego podawania białka leczniczego |
| CA3199230A1 (en) * | 2020-10-22 | 2022-04-28 | Visgenx, Inc. | Elovl2 constructs for human gene therapy |
| JP2025540499A (ja) * | 2022-12-05 | 2025-12-11 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 色素上皮由来因子ペプチドおよび網膜変性症を処置するための使用 |
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| US5932479A (en) | 1988-09-26 | 1999-08-03 | Auburn University | Genetic engineering of plant chloroplasts |
| ATE246935T1 (de) * | 1997-06-11 | 2003-08-15 | Acorda Therapeutics | Zns neuroregenerative zusammensetzungen und deren verwendungen |
| WO2001072959A2 (en) | 2000-03-01 | 2001-10-04 | Auburn University | Plastid transformation vectors for expressing human proteins in plants |
| JP2002534139A (ja) * | 1999-01-05 | 2002-10-15 | マサチューセッツ・アイ・アンド・イア・インファーマリー | 網膜と脈絡膜への経強膜徐放性薬剤標的送達 |
| WO2000054813A2 (en) * | 1999-03-15 | 2000-09-21 | Chiron Corporation | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| US6943153B1 (en) * | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| CA2401855A1 (en) | 2000-02-29 | 2001-09-07 | Auburn University | Genetic engineering of drought tolerance via a plastid genome |
| US7354760B2 (en) | 2001-12-26 | 2008-04-08 | University Of Central Florida Research Foundation, Inc. | Expression of protective antigens in transgenic chloroplasts |
| AU2003253781A1 (en) | 2002-07-03 | 2004-01-23 | University Of Central Florida | Expression of human interferon in transgenic chloroplasts |
| WO2006101634A1 (en) * | 2005-02-17 | 2006-09-28 | The Regents Of The University Of California | Müller cell specific gene therapy |
| US20060188481A1 (en) * | 2005-02-22 | 2006-08-24 | Saitama Medical School | Methods for prophylactically or therapeutically treating an animal for an ocular-related disorder |
| JP2008537478A (ja) * | 2005-02-24 | 2008-09-18 | ザ・スクリプス・リサーチ・インステイチユート | 単離骨髄球様骨髄細胞集団及びそれを用いた治療方法 |
| EP1885173A4 (en) | 2005-05-27 | 2009-02-18 | Univ Central Florida | CHLOROPLASTE DEVELOPED FOR THE EXPRESSION OF PHARMACEUTICAL PROTEINS |
| CN101980668A (zh) * | 2008-02-07 | 2011-02-23 | 赛拉基因公司 | 通过玻璃体内施用编码治疗用蛋白质的表达载体救援光感器 |
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- 2009-02-05 EP EP09707354A patent/EP2247258A4/en not_active Withdrawn
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| US8242093B2 (en) | 2012-08-14 |
| WO2009100253A1 (en) | 2009-08-13 |
| EP2247258A4 (en) | 2012-01-18 |
| US20120316112A1 (en) | 2012-12-13 |
| AU2009212309A1 (en) | 2009-08-13 |
| US8420619B2 (en) | 2013-04-16 |
| JP2011511090A (ja) | 2011-04-07 |
| CN101980668A (zh) | 2011-02-23 |
| AU2009212309B2 (en) | 2014-04-03 |
| WO2009100253A8 (en) | 2010-08-19 |
| US20090202505A1 (en) | 2009-08-13 |
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