CA2709411A1 - Binding agents to the integrin alpha-11 subunit, and uses thereof - Google Patents
Binding agents to the integrin alpha-11 subunit, and uses thereof Download PDFInfo
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- CA2709411A1 CA2709411A1 CA2709411A CA2709411A CA2709411A1 CA 2709411 A1 CA2709411 A1 CA 2709411A1 CA 2709411 A CA2709411 A CA 2709411A CA 2709411 A CA2709411 A CA 2709411A CA 2709411 A1 CA2709411 A1 CA 2709411A1
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Classifications
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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- A—HUMAN NECESSITIES
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87538906P | 2006-12-18 | 2006-12-18 | |
| US87538806P | 2006-12-18 | 2006-12-18 | |
| GB0625165A GB0625165D0 (en) | 2006-12-18 | 2006-12-18 | Novel binding agents and uses thereof |
| GB0625144.1 | 2006-12-18 | ||
| US60/875,389 | 2006-12-18 | ||
| US60/875,388 | 2006-12-18 | ||
| GB0625165.6 | 2006-12-18 | ||
| GB0625144A GB0625144D0 (en) | 2006-12-18 | 2006-12-18 | Novel binding agents |
| PCT/GB2007/004886 WO2008075045A1 (en) | 2006-12-18 | 2007-12-18 | Binding agents to the integrin alpha-11 subunit, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2709411A1 true CA2709411A1 (en) | 2008-06-26 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2709411A Abandoned CA2709411A1 (en) | 2006-12-18 | 2007-12-18 | Binding agents to the integrin alpha-11 subunit, and uses thereof |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20110256061A1 (enExample) |
| EP (1) | EP2101818A1 (enExample) |
| JP (1) | JP2010514413A (enExample) |
| AU (1) | AU2007335988A1 (enExample) |
| CA (1) | CA2709411A1 (enExample) |
| WO (1) | WO2008075045A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030055231A1 (en) | 1998-10-28 | 2003-03-20 | Jian Ni | 12 human secreted proteins |
| WO2015035235A1 (en) | 2013-09-06 | 2015-03-12 | Consejo Nacional De Investigaciones Cientificas Y Tecnicas (Conicet) | Compositions and methods for increasing mesenchymal stromal cell migration to tumors |
| EP3517549A1 (en) * | 2018-01-24 | 2019-07-31 | Bergen Teknologioverforing AS | Antibody against alpha-11 integrin and its use |
| EP3524625A1 (en) | 2018-02-08 | 2019-08-14 | Bergen Teknologioverforing AS | Antibody against alpha-11 integrin and its use |
| JP7440718B2 (ja) * | 2018-03-01 | 2024-02-29 | 恭之 横崎 | 抗インテグリンα11モノクローナル抗体、およびその利用 |
| WO2021127500A1 (en) * | 2019-12-20 | 2021-06-24 | Momenta Pharmaceuticals, Inc. | Antibodies against integrin alpha 11 beta 1 |
| JPWO2023238845A1 (enExample) * | 2022-06-07 | 2023-12-14 | ||
| CN120265657A (zh) * | 2022-10-24 | 2025-07-04 | 纤维治疗公司 | 与整合素α11结合的抗体及其用途 |
| WO2025129201A1 (en) | 2023-12-15 | 2025-06-19 | Capstan Therapeutics, Inc. | Humanized anti-cd8 antibodies and uses thereof |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9902056D0 (sv) * | 1999-06-03 | 1999-06-03 | Active Biotech Ab | An integrin heterodimer and an alpha subunit thereof |
| US6812339B1 (en) * | 2000-09-08 | 2004-11-02 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| CA2480326A1 (en) * | 2002-04-12 | 2003-12-11 | Cartela Ab | Knockout mice and their use |
| WO2006075784A1 (ja) * | 2005-01-13 | 2006-07-20 | Gene Techno Science Co., Ltd. | 抗α9インテグリン抗体とその用途 |
| WO2008075038A1 (en) * | 2006-12-18 | 2008-06-26 | Bioinvent International Ab | Binding agents to the integrin alpha-11 subunit |
-
2007
- 2007-12-18 JP JP2009542211A patent/JP2010514413A/ja active Pending
- 2007-12-18 US US12/448,342 patent/US20110256061A1/en not_active Abandoned
- 2007-12-18 EP EP07848615A patent/EP2101818A1/en not_active Withdrawn
- 2007-12-18 CA CA2709411A patent/CA2709411A1/en not_active Abandoned
- 2007-12-18 AU AU2007335988A patent/AU2007335988A1/en not_active Abandoned
- 2007-12-18 WO PCT/GB2007/004886 patent/WO2008075045A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008075045A1 (en) | 2008-06-26 |
| EP2101818A1 (en) | 2009-09-23 |
| US20110256061A1 (en) | 2011-10-20 |
| AU2007335988A1 (en) | 2008-06-26 |
| JP2010514413A (ja) | 2010-05-06 |
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