CA2696139C - Materials and methods for delivering compositions to selected tissues - Google Patents

Materials and methods for delivering compositions to selected tissues Download PDF

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Publication number
CA2696139C
CA2696139C CA2696139A CA2696139A CA2696139C CA 2696139 C CA2696139 C CA 2696139C CA 2696139 A CA2696139 A CA 2696139A CA 2696139 A CA2696139 A CA 2696139A CA 2696139 C CA2696139 C CA 2696139C
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Canada
Prior art keywords
porous
drug
particles
pores
silicon
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Active
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CA2696139A
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English (en)
French (fr)
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CA2696139A1 (en
Inventor
William R. Freeman
Michael J. Sailor
Lingyun Cheng
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University of California, San Diego
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University of California, San Diego
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Priority to CA2905205A priority Critical patent/CA2905205A1/en
Publication of CA2696139A1 publication Critical patent/CA2696139A1/en
Application granted granted Critical
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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    • A61K39/44—Antibodies bound to carriers
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    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
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    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25F—PROCESSES FOR THE ELECTROLYTIC REMOVAL OF MATERIALS FROM OBJECTS; APPARATUS THEREFOR
    • C25F3/00—Electrolytic etching or polishing
    • C25F3/02—Etching
    • C25F3/12—Etching of semiconducting materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
CA2696139A 2007-07-10 2008-07-09 Materials and methods for delivering compositions to selected tissues Active CA2696139C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2905205A CA2905205A1 (en) 2007-07-10 2008-07-09 A drug delivery device comprising a porous sio2 film or a sio2/polymer film

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94881607P 2007-07-10 2007-07-10
US60/948,816 2007-07-10
PCT/US2008/069474 WO2009009563A2 (en) 2007-07-10 2008-07-09 Materials and methods for delivering compositions to selected tissues

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2905205A Division CA2905205A1 (en) 2007-07-10 2008-07-09 A drug delivery device comprising a porous sio2 film or a sio2/polymer film

Publications (2)

Publication Number Publication Date
CA2696139A1 CA2696139A1 (en) 2009-01-15
CA2696139C true CA2696139C (en) 2018-04-17

Family

ID=40229452

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2696139A Active CA2696139C (en) 2007-07-10 2008-07-09 Materials and methods for delivering compositions to selected tissues
CA2905205A Abandoned CA2905205A1 (en) 2007-07-10 2008-07-09 A drug delivery device comprising a porous sio2 film or a sio2/polymer film

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2905205A Abandoned CA2905205A1 (en) 2007-07-10 2008-07-09 A drug delivery device comprising a porous sio2 film or a sio2/polymer film

Country Status (9)

Country Link
US (4) US20100196435A1 (enExample)
EP (1) EP2178499B1 (enExample)
JP (3) JP6067207B2 (enExample)
KR (3) KR20170084358A (enExample)
CN (1) CN101815504B (enExample)
AU (1) AU2008275181B2 (enExample)
CA (2) CA2696139C (enExample)
NZ (1) NZ583120A (enExample)
WO (1) WO2009009563A2 (enExample)

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EP1817003B1 (en) 2004-10-29 2018-02-21 The Regents of The University of California Porous silicon microparticles for drug delivery to the eye
US20100196435A1 (en) 2007-07-10 2010-08-05 The Regents Of The University Of California Materials and methods for delivering compositions to selected tissues
EP2397114B1 (en) 2009-02-10 2021-06-16 Senju Pharmaceutical Co., Ltd. Ring-shaped device
KR101137886B1 (ko) * 2009-04-24 2012-04-25 조선대학교산학협력단 다공성 실리콘 입자를 이용한 영상진단 약물전달체 및 그의 제조방법
EP2427179A4 (en) * 2009-05-04 2013-09-11 Psivida Inc POROUS PARTICLES FOR THE RELEASE OF SILICIUM MEDICINES
GB201003939D0 (en) * 2010-03-09 2010-04-21 Isis Innovation Multi-spectral scanning system
EP2590605A1 (en) 2010-07-09 2013-05-15 Board of Regents of the University of Texas System Biodegradable scaffolds
RU2640918C2 (ru) * 2010-11-01 2018-01-12 Псивида Юэс, Инк. Биоразлагаемые устройства на основе кремния для доставки терапевтических агентов
US9394369B2 (en) 2011-01-03 2016-07-19 The Regents Of The University Of California Luminescent porous silicon nanoparticles for targeted delivery and immunization
AU2012214146A1 (en) * 2011-02-11 2013-08-29 Psivida Us, Inc. Methods of treating macular edema using antiedema therapeutics
FR2972461B1 (fr) 2011-03-09 2021-01-01 Inst Nat Sciences Appliquees Lyon Procede de fabrication de nanoparticules semi-conductrices
WO2012141953A1 (en) 2011-04-07 2012-10-18 Novartis Ag Optical structures with nanostructre features and methods of use and manufacture
HK1203474A1 (en) * 2011-12-22 2015-10-30 Nanoco Technologies Limited Surface modified nanoparticles
US9708660B2 (en) * 2012-02-19 2017-07-18 Nvigen, Inc. Uses of IDed nanostructures in nucleic acid technology
FR2988721B1 (fr) 2012-03-27 2014-04-04 Centre Nat Rech Scient Nanoparticules de silicium poreux fonctionnalisees et leurs utilisations en therapie photodynamique
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