CA2692861A1 - Cd44 splice variants in neurodegenerative diseases - Google Patents
Cd44 splice variants in neurodegenerative diseases Download PDFInfo
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- CA2692861A1 CA2692861A1 CA 2692861 CA2692861A CA2692861A1 CA 2692861 A1 CA2692861 A1 CA 2692861A1 CA 2692861 CA2692861 CA 2692861 CA 2692861 A CA2692861 A CA 2692861A CA 2692861 A1 CA2692861 A1 CA 2692861A1
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
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- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
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Applications Claiming Priority (3)
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US92970607P | 2007-07-10 | 2007-07-10 | |
US60/929,706 | 2007-07-10 | ||
PCT/IB2008/052786 WO2009007934A2 (en) | 2007-07-10 | 2008-07-10 | Cd44 splice variants in neurodegenerative diseases |
Publications (1)
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CA2692861A1 true CA2692861A1 (en) | 2009-01-15 |
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Family Applications (1)
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CA 2692861 Abandoned CA2692861A1 (en) | 2007-07-10 | 2008-07-10 | Cd44 splice variants in neurodegenerative diseases |
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US (2) | US9018180B2 (ko) |
EP (1) | EP2167692B1 (ko) |
JP (1) | JP2010532989A (ko) |
KR (1) | KR20100044793A (ko) |
CN (1) | CN101821407B (ko) |
AU (1) | AU2008273713B2 (ko) |
BR (1) | BRPI0814685A2 (ko) |
CA (1) | CA2692861A1 (ko) |
EA (1) | EA201070108A1 (ko) |
ES (1) | ES2423182T3 (ko) |
HK (1) | HK1145856A1 (ko) |
IL (1) | IL203130A (ko) |
MX (1) | MX2010000236A (ko) |
NZ (1) | NZ582390A (ko) |
WO (1) | WO2009007934A2 (ko) |
ZA (1) | ZA201000083B (ko) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
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EP2229391B1 (en) | 2007-12-19 | 2014-08-06 | Cancer Research Technology Limited | Pyrido[2,3-b]pyrazine-8-substituted compounds and their use |
PL2531502T3 (pl) | 2010-02-01 | 2014-08-29 | Cancer Research Tech Ltd | 1-(5-tert-Butylo-2-fenylo-2H-pirazol-3-ilo)-3-[2-fluoro-4-(1-metylo-2-okso-2,3-dihydro-1H-imidazo[4,5-b]pirydyn-7-yloksy)-fenylo]-mocznik i związki pokrewne oraz ich zastosowanie w terapii |
JP5960793B2 (ja) * | 2011-03-24 | 2016-08-02 | ニューリム ファーマシューティカルズ(1991)リミテッド | 神経保護ペプチド |
US9399779B2 (en) * | 2011-06-08 | 2016-07-26 | The Corporation Of Mercer University | Alternative splicing constructs and methods of use |
CN104277092B (zh) * | 2013-07-12 | 2017-10-31 | 天津医科大学 | 用于预防和/或治疗老年性痴呆的β片层阻断肽 |
GB201320732D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Methods of chemical synthesis |
GB201320729D0 (en) | 2013-11-25 | 2014-01-08 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
WO2016033774A1 (zh) | 2014-09-04 | 2016-03-10 | 天津医科大学 | 用于预防和/或治疗阿尔茨海默病的β片层阻断肽 |
CN107815438A (zh) * | 2017-08-02 | 2018-03-20 | 清华大学 | 重组细胞、筛选l型钙通道调节剂的方法、试剂在制备药物中的用途和药物组合物 |
AU2022272870A1 (en) | 2021-05-11 | 2023-11-02 | Neurim Pharmaceuticals (1991) Ltd. | Method for diagnosing and treating subjects having single nucleotide polymorphisms in chromosome 2, 2:107,510,000-107,540,000 locus |
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US5990299A (en) | 1995-08-14 | 1999-11-23 | Icn Pharmaceuticals, Inc. | Control of CD44 gene expression for therapeutic use |
US6506559B1 (en) | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
US6150162A (en) | 1998-12-17 | 2000-11-21 | Isis Pharmaceuticals Inc. | Antisense modulation of CD44 expression |
IL133647A0 (en) | 1999-06-08 | 2001-04-30 | Yissum Res Dev Co | Novel cd44 variant |
WO2002081628A2 (en) * | 2001-04-05 | 2002-10-17 | Ribozyme Pharmaceuticals, Incorporated | Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies |
AU2001249622B2 (en) | 2000-03-30 | 2007-06-07 | Massachusetts Institute Of Technology | RNA sequence-specific mediators of RNA interference |
WO2002044321A2 (en) * | 2000-12-01 | 2002-06-06 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Rna interference mediating small rna molecules |
EP1383543A4 (en) | 2001-03-23 | 2006-06-21 | Agy Therapeutics Inc | USE OF BIOMOLECULAR TARGETS IN THE TREATMENT AND VISUALIZATION OF BRAIN TUMORS |
JP2005515157A (ja) | 2001-05-25 | 2005-05-26 | トマス ジェファソン ユニバーシティ | 多様な治療様式のための主成分としての選択的スプライスフォーム |
US7833779B2 (en) | 2001-07-25 | 2010-11-16 | Jivan Biologies Inc. | Methods and systems for polynucleotide detection |
US20060223065A1 (en) | 2003-09-30 | 2006-10-05 | Evotec Neuroscience Gmbh | Diagnostic and therapeutic use of a sulfotransferase for neurodegenerative diseases |
JP2008546379A (ja) | 2005-06-16 | 2008-12-25 | エボテツク・ニユーロサイエンシーズ・ゲー・エム・ベー・ハー | 神経変性疾患のための診断および治療の標的adarb2タンパク質 |
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2008
- 2008-07-10 AU AU2008273713A patent/AU2008273713B2/en active Active
- 2008-07-10 BR BRPI0814685A patent/BRPI0814685A2/pt not_active IP Right Cessation
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- 2008-07-10 CN CN2008801049431A patent/CN101821407B/zh active Active
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- 2008-07-10 EA EA201070108A patent/EA201070108A1/ru unknown
- 2008-07-10 US US12/668,563 patent/US9018180B2/en active Active
- 2008-07-10 KR KR1020107001642A patent/KR20100044793A/ko not_active Application Discontinuation
- 2008-07-10 CA CA 2692861 patent/CA2692861A1/en not_active Abandoned
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2010
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2011
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Also Published As
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CN101821407A (zh) | 2010-09-01 |
MX2010000236A (es) | 2010-06-02 |
US9018180B2 (en) | 2015-04-28 |
EP2167692B1 (en) | 2013-05-22 |
JP2010532989A (ja) | 2010-10-21 |
WO2009007934A3 (en) | 2009-05-07 |
CN101821407B (zh) | 2013-09-18 |
BRPI0814685A2 (pt) | 2019-09-24 |
AU2008273713B2 (en) | 2014-07-03 |
US9416166B2 (en) | 2016-08-16 |
HK1145856A1 (en) | 2011-05-06 |
NZ582390A (en) | 2012-05-25 |
EA201070108A1 (ru) | 2010-06-30 |
IL203130A (en) | 2014-07-31 |
ES2423182T3 (es) | 2013-09-18 |
WO2009007934A2 (en) | 2009-01-15 |
US20150266940A1 (en) | 2015-09-24 |
AU2008273713A1 (en) | 2009-01-15 |
KR20100044793A (ko) | 2010-04-30 |
ZA201000083B (en) | 2011-03-30 |
US20110172286A1 (en) | 2011-07-14 |
EP2167692A2 (en) | 2010-03-31 |
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