CA2682962A1 - .delta.9 elongases and their use in making polyunsaturated fatty acids - Google Patents

.delta.9 elongases and their use in making polyunsaturated fatty acids Download PDF

Info

Publication number
CA2682962A1
CA2682962A1 CA002682962A CA2682962A CA2682962A1 CA 2682962 A1 CA2682962 A1 CA 2682962A1 CA 002682962 A CA002682962 A CA 002682962A CA 2682962 A CA2682962 A CA 2682962A CA 2682962 A1 CA2682962 A1 CA 2682962A1
Authority
CA
Canada
Prior art keywords
seq
elongase
sequence
acid
host cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002682962A
Other languages
English (en)
French (fr)
Inventor
Howard Glenn Damude
Quinn Qun Zhu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2682962A1 publication Critical patent/CA2682962A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings or cooking oils
    • A23D9/007Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/158Fatty acids; Fats; Products containing oils or fats
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
CA002682962A 2007-04-16 2008-04-16 .delta.9 elongases and their use in making polyunsaturated fatty acids Abandoned CA2682962A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91192507P 2007-04-16 2007-04-16
US60/911,925 2007-04-16
PCT/US2008/060396 WO2008128241A1 (en) 2007-04-16 2008-04-16 Delta 9 elongases and their use in making polyunsaturated fatty acids

Publications (1)

Publication Number Publication Date
CA2682962A1 true CA2682962A1 (en) 2008-10-23

Family

ID=39619289

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002682962A Abandoned CA2682962A1 (en) 2007-04-16 2008-04-16 .delta.9 elongases and their use in making polyunsaturated fatty acids
CA002679485A Abandoned CA2679485A1 (en) 2007-04-16 2008-04-16 Delta-9 elongases and their use in making polyunsaturated fatty acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002679485A Abandoned CA2679485A1 (en) 2007-04-16 2008-04-16 Delta-9 elongases and their use in making polyunsaturated fatty acids

Country Status (9)

Country Link
US (5) US7794701B2 (cg-RX-API-DMAC7.html)
EP (2) EP2137304B1 (cg-RX-API-DMAC7.html)
JP (1) JP5501954B2 (cg-RX-API-DMAC7.html)
CN (1) CN101848996B (cg-RX-API-DMAC7.html)
AU (2) AU2008240028B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0807291A2 (cg-RX-API-DMAC7.html)
CA (2) CA2682962A1 (cg-RX-API-DMAC7.html)
DK (1) DK2137304T3 (cg-RX-API-DMAC7.html)
WO (2) WO2008128241A1 (cg-RX-API-DMAC7.html)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005103253A1 (en) 2004-04-22 2005-11-03 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
RU2009111266A (ru) 2006-08-29 2010-10-10 Коммонвелт Сайентифик энд Индастриал Рисерч Организейшн (AU) Синтез жирных кислот
US7794701B2 (en) 2007-04-16 2010-09-14 E.I. Du Pont De Nemours And Company Δ-9 elongases and their use in making polyunsaturated fatty acids
DK2169055T3 (da) * 2007-05-25 2015-06-22 Suntory Holdings Ltd Nyt lysophosphatidat-acyltransferasegen.
US8168858B2 (en) 2008-06-20 2012-05-01 E. I. Du Pont De Nemours And Company Delta-9 fatty acid elongase genes and their use in making polyunsaturated fatty acids
AU2009317860B2 (en) 2008-11-18 2014-03-27 Commonwealth Scientific And Industrial Research Organisation Enzymes and methods for producing omega-3 fatty acids
US9175318B2 (en) * 2008-12-18 2015-11-03 E. I. Dupont De Nemours And Company Reducing byproduction of malonates by yeast in a fermentation process
CN102595917A (zh) 2009-06-16 2012-07-18 纳幕尔杜邦公司 来自改善的优化的解脂耶氏酵母菌株的高二十碳五烯酸油
US8188335B2 (en) * 2009-07-17 2012-05-29 Abbott Laboratories Δ9-elongase for production of polyunsaturated fatty acid-enriched oils
AU2010317139A1 (en) 2009-11-03 2012-05-24 Dsm Ip Assets B.V. Composition comprising cells and a polyunsaturated fatty acid having at least 20 carbon atoms (LC-PUFA)
US20130101723A1 (en) 2009-11-03 2013-04-25 Daniel Verkoeijen Vegetable oil comprising a polyunsaturated fatty acid having at least 20 carbon atoms
CA2795460A1 (en) 2010-04-22 2011-10-27 E. I. Du Pont De Nemours And Company Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass
KR20140008295A (ko) 2010-08-26 2014-01-21 이 아이 듀폰 디 네모아 앤드 캄파니 돌연변이 델타-9 연장효소 및 다중불포화 지방산의 제조에서의 그들의 용도
AU2011293180B2 (en) 2010-08-26 2017-03-02 E. I. Du Pont De Nemours And Company Recombinant microbial host cells for high eicosapentaenoic acid production
US8658413B2 (en) 2010-08-26 2014-02-25 E I Du Pont De Nemours And Company Mutant HPGG motif and HDASH motif delta-5 desaturases and their use in making polyunsaturated fatty acids
US8735137B2 (en) 2010-12-30 2014-05-27 E I Du Pont De Nemours And Company Use of Saccharomyces cerevisiae SUC2 gene in Yarrowia lipolytica for sucrose utilization
US20130040340A1 (en) 2011-02-07 2013-02-14 E. I. Du Pont De Nemours And Company Production of alcohol esters in situ using alcohols and fatty acids produced by microorganisms
US8816111B2 (en) 2012-06-15 2014-08-26 Commonwealth Scientific And Industrial Research Organisation Lipid comprising polyunsaturated fatty acids
EP2935591B1 (en) 2012-12-21 2017-07-05 E. I. du Pont de Nemours and Company Down-regulation of a polynucleotide encoding a sou2 sorbitol utilization protein to modify lipid production in microbial cells
US20160272997A1 (en) 2013-10-25 2016-09-22 Pioneer Hi-Bred International, Inc. Stem canker tolerant soybeans and methods of use
WO2015196250A1 (en) 2014-06-27 2015-12-30 Commonwealth Scientific And Industrial Research Organisation Lipid comprising docosapentaenoic acid
AU2014366839B2 (en) 2013-12-18 2021-07-01 Commonwealth Scientific And Industrial Research Organisation Lipid comprising long chain polyunsaturated fatty acids
CN106916796B (zh) * 2015-12-28 2021-06-29 丰益(上海)生物技术研发中心有限公司 裂殖壶菌delta-12脂肪酸脱饱和酶相关序列及其应用
WO2017136204A1 (en) 2016-02-05 2017-08-10 Pioneer Hi-Bred International, Inc. Genetic loci associated with brown stem rot resistance in soybean and methods of use
CN110087481A (zh) 2016-12-15 2019-08-02 帝斯曼知识产权资产管理有限公司 包含硅酸盐和含具有至少20个碳原子的多不饱和脂肪酸(lc-pufa)的微生物细胞和/或植物细胞的共混物制剂

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670285A (en) 1982-08-06 1987-06-02 The University Of Toronto Innovations Foundation Infant formula
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5107065A (en) 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
US5188958A (en) 1986-05-29 1993-02-23 Calgene, Inc. Transformation and foreign gene expression in brassica species
US5004863B2 (en) 1986-12-03 2000-10-17 Agracetus Genetic engineering of cotton plants and lines
JP2527340B2 (ja) 1986-12-15 1996-08-21 アプライド バイオシステムズ インコーポレイテッド ロ―ダミン染料の5−及び6−スクシニミジルカルボキシレ―ト異性体
US5416011A (en) 1988-07-22 1995-05-16 Monsanto Company Method for soybean transformation and regeneration
US5366860A (en) 1989-09-29 1994-11-22 Applied Biosystems, Inc. Spectrally resolvable rhodamine dyes for nucleic acid sequence determination
AU1871492A (en) 1991-03-29 1992-11-02 Board Of Trustees Of The University Of Illinois, The Production fo transgenic soybean plants
US6372965B1 (en) 1992-11-17 2002-04-16 E.I. Du Pont De Nemours And Company Genes for microsomal delta-12 fatty acid desaturases and hydroxylases from plants
US5648564A (en) 1995-12-21 1997-07-15 Kemin Industries, Inc. Process for the formation, isolation and purification of comestible xanthophyll crystals from plants
US6075183A (en) 1997-04-11 2000-06-13 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US5968809A (en) 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US5972664A (en) 1997-04-11 1999-10-26 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
US6051754A (en) 1997-04-11 2000-04-18 Abbott Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids in plants
US6432684B1 (en) 1997-04-11 2002-08-13 Abbott Laboratories Human desaturase gene and uses thereof
TR199902474T2 (xx) 1997-04-11 2000-02-21 Calgene Llc Bitkilerde uzun zincirli �ok-doymam�� ya�l� asitlerin sentezi i�in y�ntemler ve bile�imler.
US6403349B1 (en) 1998-09-02 2002-06-11 Abbott Laboratories Elongase gene and uses thereof
US6825017B1 (en) 1998-12-07 2004-11-30 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
EP1147174B1 (en) 1998-12-07 2007-02-14 Washington State University Research Foundation Desaturases and methods of using them for synthesis of polyunsaturated fatty acids
EP1297163B1 (en) 2000-06-23 2011-04-27 E.I. Du Pont De Nemours And Company Recombinant constructs and their use in reducing gene expression
SI1309698T1 (sl) 2000-07-21 2007-08-31 Du Pont Citokrom p450 encim zdruĺ˝en s sintezo delta-12-epoksi skupin v maĺ äśobnih kislinah rastlin
CA2441265A1 (en) * 2001-03-16 2002-09-26 Basf Plant Science Gmbh Sugar and lipid metabolism regulators in plants
GB0107510D0 (en) * 2001-03-26 2001-05-16 Univ Bristol New elongase gene and a process for the production of -9-polyunsaturated fatty acids
TWI350854B (en) 2001-04-16 2011-10-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
US6797303B2 (en) 2001-09-04 2004-09-28 Lycored Natural Products Industries Ltd. Carotenoid extraction process
AU2003296638B2 (en) * 2002-12-19 2009-06-11 University Of Bristol Method for the production of polyunsaturated fatty acids
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
US7129089B2 (en) 2003-02-12 2006-10-31 E. I. Du Pont De Nemours And Company Annexin and P34 promoters and use in expression of transgenic genes in plants
US7125672B2 (en) 2003-05-07 2006-10-24 E. I. Du Pont De Nemours And Company Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts
US7238482B2 (en) * 2003-05-07 2007-07-03 E. I. Du Pont De Nemours And Company Production of polyunsaturated fatty acids in oleaginous yeasts
US7259255B2 (en) 2003-06-25 2007-08-21 E. I. Du Pont De Nemours And Company Glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate mutase promoters for gene expression in oleaginous yeast
MX342029B (es) 2003-08-01 2016-09-12 Basf Plant Science Gmbh * Metodo para la produccion de acidos grasos poli - insaturados en organismos transgenicos.
CA2542574C (en) 2003-11-12 2014-03-18 E. I. Du Pont De Nemours And Company Delta-15 desaturases suitable for altering levels of polyunsaturated fatty acids in oleaginous plants and yeast
WO2005049805A2 (en) 2003-11-14 2005-06-02 E.I. Dupont De Nemours And Company Fructose-bisphosphate aldolase regulatory sequences for gene expression in oleaginous yeast
EP1723220B1 (de) 2004-02-27 2013-04-10 BASF Plant Science GmbH Verfahren zur herstellung mehrfach ungesättigter fettsäuren in transgenen pflanzen
WO2005103253A1 (en) 2004-04-22 2005-11-03 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
US7807849B2 (en) 2004-04-22 2010-10-05 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
EP1758991B1 (en) * 2004-06-25 2013-01-16 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7465564B2 (en) * 2004-08-10 2008-12-16 E.I. Du Pont De Nemours And Company Production of γ-linolenic acid in oleaginous yeast
US7588931B2 (en) * 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
AU2006316610B2 (en) * 2005-11-23 2012-06-14 E. I. Du Pont De Nemours And Company Delta-9 elongases and their use in making polyunsaturated fatty acids
US7465793B2 (en) * 2006-04-20 2008-12-16 E.I. Du Pont De Nemours And Company Synthetic Δ17 desaturase derived from Phytophthora ramourum and its use in making polyunsaturated fatty acids
US7943823B2 (en) 2006-04-28 2011-05-17 E.I. Du Pont De Nemours And Company Delta-8 desaturase and its use in making polyunsaturated fatty acids
US7678560B2 (en) 2006-05-17 2010-03-16 E.I. Du Pont De Nemours And Company Δ 5 desaturase and its use in making polyunsaturated fatty acids
UA102063C2 (uk) * 2007-02-12 2013-06-10 Е. І. Дю Пон Де Немур Енд Компані Трансгенна соєва рослина, що продукує арахідонову кислоту
UA103595C2 (uk) * 2007-04-03 2013-11-11 Е. І. Дю Пон Де Немур Енд Компані Мультизими і їх застосування в отриманні поліненасичених жирних кислот
US7790156B2 (en) * 2007-04-10 2010-09-07 E. I. Du Pont De Nemours And Company Δ-8 desaturases and their use in making polyunsaturated fatty acids
US7794701B2 (en) * 2007-04-16 2010-09-14 E.I. Du Pont De Nemours And Company Δ-9 elongases and their use in making polyunsaturated fatty acids
CN101970638B (zh) * 2007-10-03 2015-02-11 纳幕尔杜邦公司 用于高水平生产二十碳五烯酸的优化解脂耶氏酵母菌株
EP2274429B1 (en) * 2008-04-03 2014-10-22 E. I. du Pont de Nemours and Company Multizymes
CN102596320B (zh) 2009-10-30 2016-09-07 瑞蔻医药有限公司 通过经皮超声波去肾神经治疗高血压的方法和装置
US9979908B2 (en) 2014-03-31 2018-05-22 Agency For Science, Technology And Research Image processing devices and image processing methods with interpolation for improving image resolution

Also Published As

Publication number Publication date
EP2137304B1 (en) 2013-08-14
EP2137304A1 (en) 2009-12-30
AU2008240029A1 (en) 2008-10-23
US7794701B2 (en) 2010-09-14
US8377673B2 (en) 2013-02-19
US20100267098A1 (en) 2010-10-21
EP2134837A1 (en) 2009-12-23
US20120100595A1 (en) 2012-04-26
WO2008128240A1 (en) 2008-10-23
JP2010524468A (ja) 2010-07-22
JP5501954B2 (ja) 2014-05-28
AU2008240028B2 (en) 2014-03-06
US8119860B2 (en) 2012-02-21
BRPI0807291A2 (pt) 2014-04-29
AU2008240028A1 (en) 2008-10-23
US20100162435A1 (en) 2010-06-24
US20080254195A1 (en) 2008-10-16
CN101848996B (zh) 2013-05-29
CA2679485A1 (en) 2008-10-23
EP2134837B1 (en) 2014-01-01
US8298797B2 (en) 2012-10-30
US20080254522A1 (en) 2008-10-16
AU2008240029B2 (en) 2013-05-02
WO2008128241A1 (en) 2008-10-23
DK2137304T3 (da) 2013-11-11
CN101848996A (zh) 2010-09-29

Similar Documents

Publication Publication Date Title
AU2008240029B2 (en) Delta 9 elongases and their use in making polyunsaturated fatty acids
US8318463B2 (en) Δ8 desaturases and their use in making polyunsaturated fatty acids
US7943365B2 (en) Δ-5 desaturases and their use in making polyunsaturated fatty acids
US7678560B2 (en) Δ 5 desaturase and its use in making polyunsaturated fatty acids
US8241884B2 (en) Δ17 desaturase and its use in making polyunsaturated fatty acids
EP2259674B1 (en) Delta-4 desaturase and its use in making polyunsaturated fatty acids
EP2087106A1 (en) Mutant delta8 desaturase genes engineered by targeted mutagenesis and their use in making polyunsaturated fatty acids
JP2009534032A (ja) Δ17デサチュラーゼおよび多価不飽和脂肪酸の製造におけるそれらの使用
WO2010014835A1 (en) Δ6 desaturases and their use in making polyunsaturated fatty acids

Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20130327

FZDE Discontinued

Effective date: 20201002