CA2682114C - Method of determining risk of scoliosis - Google Patents

Method of determining risk of scoliosis Download PDF

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Publication number
CA2682114C
CA2682114C CA2682114A CA2682114A CA2682114C CA 2682114 C CA2682114 C CA 2682114C CA 2682114 A CA2682114 A CA 2682114A CA 2682114 A CA2682114 A CA 2682114A CA 2682114 C CA2682114 C CA 2682114C
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CA
Canada
Prior art keywords
opn
scoliosis
subject
protein expression
biological fluid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2682114A
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English (en)
French (fr)
Other versions
CA2682114A1 (en
Inventor
Alain Moreau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre Hospitalier Universitaire Saint Justine
Original Assignee
Centre Hospitalier Universitaire Saint Justine
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Publication of CA2682114A1 publication Critical patent/CA2682114A1/en
Application granted granted Critical
Publication of CA2682114C publication Critical patent/CA2682114C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F5/00—Orthopaedic methods or devices for non-surgical treatment of bones or joints; Nursing devices ; Anti-rape devices
    • A61F5/01—Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
    • A61F5/0102—Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces specially adapted for correcting deformities of the limbs or for supporting them; Ortheses, e.g. with articulations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/108—Osteoporosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Nursing (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
CA2682114A 2007-03-30 2008-03-31 Method of determining risk of scoliosis Expired - Fee Related CA2682114C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90940807P 2007-03-30 2007-03-30
US60/909,408 2007-03-30
US2557108P 2008-02-01 2008-02-01
US61/025,571 2008-02-01
PCT/CA2008/000595 WO2008119170A1 (en) 2007-03-30 2008-03-31 Method of determining risk of scoliosis

Publications (2)

Publication Number Publication Date
CA2682114A1 CA2682114A1 (en) 2008-10-09
CA2682114C true CA2682114C (en) 2017-08-01

Family

ID=39807753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2682114A Expired - Fee Related CA2682114C (en) 2007-03-30 2008-03-31 Method of determining risk of scoliosis

Country Status (10)

Country Link
US (3) US20100075333A1 (show.php)
EP (1) EP2132568B1 (show.php)
JP (1) JP5426530B2 (show.php)
KR (1) KR101436578B1 (show.php)
CN (1) CN101680887B (show.php)
AU (1) AU2008234374B2 (show.php)
CA (1) CA2682114C (show.php)
IL (1) IL201186A (show.php)
MX (1) MX2009010400A (show.php)
WO (1) WO2008119170A1 (show.php)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9029094B2 (en) * 2010-10-04 2015-05-12 Chu Sainte-Justine Biomechanical-based methods of diagnosing scoliosis
DE102012102338A1 (de) 2012-03-20 2013-09-26 Hauni Maschinenbau Ag Messanordnung zum Messen von in Strangmaschinen der Tabak verarbeitenden Industrie hergestellten und geförderten Strängen
US20150038511A1 (en) 2012-08-09 2015-02-05 Celgene Corporation Treatment of immune-related and inflammatory diseases
WO2014025958A2 (en) 2012-08-09 2014-02-13 Celgene Corporation Treatment of immune-related and inflammatory diseases
EP3513808A1 (en) 2013-06-17 2019-07-24 CHU Sainte-Justine A method of increasing gipcr signalization in the cells of a scoliotic subject
WO2014201557A1 (en) 2013-06-17 2014-12-24 Chu Ste-Justine Gi protein phosphorylation as marker for scoliosis and scoliosis progression, methods of increasing gipcr signaling in scoliotic subjects
AU2014284078A1 (en) 2013-06-17 2016-01-07 Chu Sainte-Justine New markers for severe progression of idiopathic scoliosis and uses thereof to stratify scoliotic patients and predict the risk of developing scoliosis
EP3647789A1 (en) * 2013-09-09 2020-05-06 Chu Sainte-Justine New marker for the classification, diagnosis and treatment of scoliosis
US10245266B2 (en) 2014-05-19 2019-04-02 Celgene Corporation 3-(4-((4-morpholinomethyl-benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione for the treatment of systemic lupus erythematosus
CN106310610A (zh) * 2016-10-21 2017-01-11 上海交通大学医学院附属新华医院 一种脊柱侧凸特定运动疗法
CN106841593B (zh) * 2017-03-24 2018-08-17 北京致成生物医学科技有限公司 Lacc1和fhl2基因在制备脊柱侧弯检测产品中的应用
CN111638329B (zh) * 2020-06-09 2021-06-01 南方医科大学 一种用于检测布鲁氏菌病elispot检测试剂盒及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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US5618920A (en) * 1985-11-01 1997-04-08 Xoma Corporation Modular assembly of antibody genes, antibodies prepared thereby and use
SE9101642D0 (sv) * 1991-05-30 1991-05-30 Kabi Pharmacia Ab Phospholipids
WO1996006622A1 (en) 1991-07-03 1996-03-07 Hyal Pharmaceutical Corporation Hyaluronic acid and derivatives for modulation of cellular activity
EP0767380A1 (de) * 1993-06-22 1997-04-09 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Verfahren zur Diagnose und Analyse von Zervixkarzinomen
US5858709A (en) * 1996-10-15 1999-01-12 Smithkline Beecham P.L.C. Fibronectin binding protein B compounds
US20020160970A1 (en) * 1996-04-10 2002-10-31 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
WO1998008379A1 (en) 1996-08-27 1998-03-05 Dana-Farber Cancer Institute Methods for identifying modulators of cellular interactions mediated by osteopontin
US6150162A (en) * 1998-12-17 2000-11-21 Isis Pharmaceuticals Inc. Antisense modulation of CD44 expression
AU3149200A (en) 1999-01-18 2000-08-01 Osteometer Biotech As Genetic predisposition
CA2370301A1 (en) * 1999-04-15 2000-10-26 Children's Medical Center Corporation Osteopontin-derived chemotactic and inhibitory agents and uses therefor
AU4256901A (en) 2000-03-23 2001-10-03 Glaxo Group Limited Method of screening for inhibitors of osteopontin
BR0213078A (pt) * 2001-09-25 2004-11-23 Fujisawa Pharmaceutical Co Anticorpo recombinante anti-osteopontina e uso do mesmo
CA2373854A1 (en) * 2002-02-28 2003-08-28 Alain Moreau Methods of diagnosing and counteracting adolescent idiopathic scoliosis
EP1532268A4 (en) * 2002-03-21 2006-07-05 Yissum Res Dev Co PERIPHERAL BLOOD CELL MARKERS SUITABLE FOR THE DIAGNOSIS OF MULTIPLE SCLEROSIS AND THESE USEFUL METHODS AND KITS
WO2004024750A2 (en) * 2002-09-13 2004-03-25 Dyax Corporation Cd44-binding ligands
US20050282163A1 (en) * 2003-02-03 2005-12-22 Medstar Research Institute Washington Hospital Center Polymorphisms in elastin, fibrillin and related genes as predisposing to restenosis and to a therosclerosis
US20090104620A1 (en) * 2007-07-03 2009-04-23 Axial Biotech, Inc. Simplified Method of Determining Predisposition to Scoliosis

Also Published As

Publication number Publication date
CN101680887A (zh) 2010-03-24
HK1132550A1 (en) 2010-02-26
US20130266966A1 (en) 2013-10-10
KR20100016075A (ko) 2010-02-12
IL201186A0 (en) 2010-05-17
AU2008234374A1 (en) 2008-10-09
US20100075333A1 (en) 2010-03-25
AU2008234374B2 (en) 2013-05-23
KR101436578B1 (ko) 2014-09-01
US10073101B2 (en) 2018-09-11
EP2132568A1 (en) 2009-12-16
US20150323553A1 (en) 2015-11-12
CA2682114A1 (en) 2008-10-09
MX2009010400A (es) 2010-02-18
CN101680887B (zh) 2014-06-25
JP5426530B2 (ja) 2014-02-26
JP2010522699A (ja) 2010-07-08
WO2008119170A1 (en) 2008-10-09
IL201186A (en) 2013-10-31
EP2132568A4 (en) 2010-06-09
EP2132568B1 (en) 2013-05-29

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