CA2676477A1 - Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole - Google Patents
Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole Download PDFInfo
- Publication number
- CA2676477A1 CA2676477A1 CA002676477A CA2676477A CA2676477A1 CA 2676477 A1 CA2676477 A1 CA 2676477A1 CA 002676477 A CA002676477 A CA 002676477A CA 2676477 A CA2676477 A CA 2676477A CA 2676477 A1 CA2676477 A1 CA 2676477A1
- Authority
- CA
- Canada
- Prior art keywords
- crystal
- methyl
- benzimidazole
- trifluoroethoxy
- sulfinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA2738458A CA2738458A1 (en) | 2007-12-31 | 2008-12-30 | Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1802107P | 2007-12-31 | 2007-12-31 | |
| US61/018,021 | 2007-12-31 | ||
| PCT/US2008/088534 WO2009088857A1 (en) | 2007-12-31 | 2008-12-30 | Crystalline solvated forms of (r) -2- [ [ [3-methyl-4- (2, 2, 2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -1h-benz imidazole |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2738458A Division CA2738458A1 (en) | 2007-12-31 | 2008-12-30 | Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2676477A1 true CA2676477A1 (en) | 2009-07-16 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002676477A Withdrawn CA2676477A1 (en) | 2007-12-31 | 2008-12-30 | Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole |
| CA2738458A Abandoned CA2738458A1 (en) | 2007-12-31 | 2008-12-30 | Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2738458A Abandoned CA2738458A1 (en) | 2007-12-31 | 2008-12-30 | Crystalline solvated forms of (r)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1h-benzimidazole |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100286400A1 (enExample) |
| EP (3) | EP2227462A1 (enExample) |
| JP (1) | JP2011507977A (enExample) |
| CA (2) | CA2676477A1 (enExample) |
| WO (1) | WO2009088857A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011020189A1 (en) * | 2009-08-19 | 2011-02-24 | Apotex Pharmachem Inc. | Forms of dexlansoprazole and processes for the preparation thereof |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009113696A1 (en) | 2008-03-10 | 2009-09-17 | Takeda Pharmaceutical Company Limited | Crystal of benzimidazole compound |
| WO2010039885A2 (en) * | 2008-09-30 | 2010-04-08 | Teva Pharmaceutical Industries Ltd. | Crystalline forms of dexlansoprazole |
| IT1391776B1 (it) | 2008-11-18 | 2012-01-27 | Dipharma Francis Srl | Procedimento per la preparazione di dexlansoprazolo |
| WO2010095144A2 (en) * | 2009-02-04 | 2010-08-26 | Msn Laboratories Limited | Process for the preparation of proton pump inhibitors |
| IT1392813B1 (it) | 2009-02-06 | 2012-03-23 | Dipharma Francis Srl | Forme cristalline di dexlansoprazolo |
| WO2011004387A2 (en) | 2009-06-18 | 2011-01-13 | Matrix Laboratories Ltd | Process for the preparation of dexlansoprazole polymorphic forms |
| IT1395118B1 (it) | 2009-07-29 | 2012-09-05 | Dipharma Francis Srl | Procedimento per la preparazione di dexlansoprazolo cristallino |
| WO2011098938A1 (en) * | 2010-02-11 | 2011-08-18 | Orchid Chemicals And Pharmaceuticals Limited | Novel solvate of dexlansoprazole |
| WO2011139414A2 (en) * | 2010-04-27 | 2011-11-10 | Dr. Reddy's Laboratories Ltd. | Dexlansoprazole polymorphic forms |
| EP2723728A1 (en) * | 2011-06-21 | 2014-04-30 | Ranbaxy Laboratories Limited | Process for the preparation of dexlansoprazole |
| CN102234265B (zh) * | 2011-08-08 | 2013-11-20 | 天津市汉康医药生物技术有限公司 | 兰索拉唑化合物 |
| WO2013140120A1 (en) | 2012-03-22 | 2013-09-26 | Cipla Limited | Glycerol solvate forms of (r) - 2 - [ [ [3 -methyl -4 (2,2, 2 - trifluoroethoxy) pyridin- 2 - yl] methyl] sulphinyl] - 1h - ben zimidazole |
| CN104177333A (zh) * | 2013-05-24 | 2014-12-03 | 四川海思科制药有限公司 | 一种理化性质稳定的(r)-2-[[[3-甲基-4-(2,2,2-三氟乙氧基)-2-吡啶基]甲基]亚磺酰基]-1h-苯并咪唑 |
| CN104650035A (zh) * | 2013-11-25 | 2015-05-27 | 天津市汉康医药生物技术有限公司 | 右兰索拉唑倍半水合物化合物 |
| US20170042806A1 (en) | 2015-04-29 | 2017-02-16 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
| US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
| IT201700050223A1 (it) | 2017-05-09 | 2018-11-09 | Dipharma Francis Srl | Procedimento per la preparazione di dexlansoprazolo cristallino |
| EP3495422B1 (en) | 2017-12-05 | 2020-11-11 | Borealis AG | Fiber reinforced polypropylene composition |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| TW385306B (en) * | 1996-11-14 | 2000-03-21 | Takeda Chemical Industries Ltd | Method for producing crystals of benzimidazole derivatives |
| JP3283252B2 (ja) | 1999-06-17 | 2002-05-20 | 武田薬品工業株式会社 | ベンズイミダゾール化合物の結晶 |
| TWI289557B (en) * | 1999-06-17 | 2007-11-11 | Takeda Chemical Industries Ltd | A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole |
| JP3374314B2 (ja) | 2000-05-15 | 2003-02-04 | 武田薬品工業株式会社 | 結晶の製造法 |
| CN1280287C (zh) * | 2000-05-15 | 2006-10-18 | 武田药品工业株式会社 | 晶体的制备方法 |
| JP4160293B2 (ja) | 2000-12-01 | 2008-10-01 | 武田薬品工業株式会社 | 結晶の製造法 |
| US6627646B2 (en) * | 2001-07-17 | 2003-09-30 | Sepracor Inc. | Norastemizole polymorphs |
| MY148805A (en) | 2002-10-16 | 2013-05-31 | Takeda Pharmaceutical | Controlled release preparation |
| AU2003273000A1 (en) * | 2002-10-16 | 2004-05-04 | Takeda Pharmaceutical Company Limited | Stable solid preparations |
| ITMI20062481A1 (it) * | 2006-12-22 | 2008-06-23 | Recordati Chem Pharm | Processo per la preparazione di lansoprazolo forma i microcristallino |
-
2008
- 2008-12-30 CA CA002676477A patent/CA2676477A1/en not_active Withdrawn
- 2008-12-30 WO PCT/US2008/088534 patent/WO2009088857A1/en not_active Ceased
- 2008-12-30 JP JP2010541519A patent/JP2011507977A/ja not_active Abandoned
- 2008-12-30 EP EP08870108A patent/EP2227462A1/en not_active Withdrawn
- 2008-12-30 US US12/811,190 patent/US20100286400A1/en not_active Abandoned
- 2008-12-30 CA CA2738458A patent/CA2738458A1/en not_active Abandoned
- 2008-12-30 EP EP10183275A patent/EP2292612A3/en not_active Withdrawn
- 2008-12-30 EP EP12192439A patent/EP2573082A1/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011020189A1 (en) * | 2009-08-19 | 2011-02-24 | Apotex Pharmachem Inc. | Forms of dexlansoprazole and processes for the preparation thereof |
| EP2467375A4 (en) * | 2009-08-19 | 2013-01-23 | Apotex Pharmachem Inc | FORMS OF DEXLANDSOPRAZOLE AND METHOD OF MANUFACTURING THEREOF |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2292612A3 (en) | 2011-05-04 |
| US20100286400A1 (en) | 2010-11-11 |
| EP2227462A1 (en) | 2010-09-15 |
| JP2011507977A (ja) | 2011-03-10 |
| EP2292612A2 (en) | 2011-03-09 |
| WO2009088857A1 (en) | 2009-07-16 |
| CA2738458A1 (en) | 2009-07-16 |
| EP2573082A1 (en) | 2013-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| AZWI | Withdrawn application |