CA2670289A1 - Use of bone marrow cells for long term culture of pancreatic islet cells - Google Patents

Use of bone marrow cells for long term culture of pancreatic islet cells Download PDF

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Publication number
CA2670289A1
CA2670289A1 CA002670289A CA2670289A CA2670289A1 CA 2670289 A1 CA2670289 A1 CA 2670289A1 CA 002670289 A CA002670289 A CA 002670289A CA 2670289 A CA2670289 A CA 2670289A CA 2670289 A1 CA2670289 A1 CA 2670289A1
Authority
CA
Canada
Prior art keywords
cell
islet
bone marrow
beta
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002670289A
Other languages
English (en)
French (fr)
Inventor
Luguang Luo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roger Williams Medical Center
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2670289A1 publication Critical patent/CA2670289A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/13Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1394Bone marrow stromal cells; whole marrow

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
CA002670289A 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells Abandoned CA2670289A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86063706P 2006-11-21 2006-11-21
US60/860,637 2006-11-21
PCT/US2007/024258 WO2008063640A2 (en) 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells

Publications (1)

Publication Number Publication Date
CA2670289A1 true CA2670289A1 (en) 2008-05-29

Family

ID=39430369

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002670289A Abandoned CA2670289A1 (en) 2006-11-21 2007-11-20 Use of bone marrow cells for long term culture of pancreatic islet cells

Country Status (7)

Country Link
US (1) US20100143306A1 (https=)
EP (1) EP2092057B1 (https=)
JP (1) JP5474559B2 (https=)
CN (2) CN101652470A (https=)
AU (1) AU2007321983B2 (https=)
CA (1) CA2670289A1 (https=)
WO (1) WO2008063640A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852934B2 (en) 2010-03-17 2014-10-07 Kyoto University Method of culturing pancreatic islet-like tissues by a tissue complex of pancreas-derived non-endocrinal epithelial cells and vascular endothelial cells
MX2020014242A (es) * 2018-06-25 2021-05-27 Imagine Pharma Llc Composiciones y métodos para propagar las células de islotes productoras de insulina y usos terapéuticos de las mismas.
AU2022217790A1 (en) * 2021-02-03 2023-09-07 Symbiocelltech, Llc Cell clusters comprising stem and islet cells, methods of making, and treatment of diabetes mellitus therewith

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001647A (en) * 1994-04-28 1999-12-14 Ixion Biotechnology, Inc. In vitro growth of functional islets of Langerhans and in vivo uses thereof
US20050208029A1 (en) * 2002-04-17 2005-09-22 Akihiro Umezawa Method of forming pancreatic beta cells from mesenchymal cells

Also Published As

Publication number Publication date
JP2010509936A (ja) 2010-04-02
AU2007321983A1 (en) 2008-05-29
WO2008063640A3 (en) 2008-12-18
EP2092057B1 (en) 2014-10-15
EP2092057A2 (en) 2009-08-26
CN103992982A (zh) 2014-08-20
CN101652470A (zh) 2010-02-17
WO2008063640A2 (en) 2008-05-29
AU2007321983B2 (en) 2014-05-29
EP2092057A4 (en) 2011-04-20
JP5474559B2 (ja) 2014-04-16
US20100143306A1 (en) 2010-06-10

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20161121