CA2669347A1 - Methods for treating pompe disease - Google Patents
Methods for treating pompe disease Download PDFInfo
- Publication number
- CA2669347A1 CA2669347A1 CA002669347A CA2669347A CA2669347A1 CA 2669347 A1 CA2669347 A1 CA 2669347A1 CA 002669347 A CA002669347 A CA 002669347A CA 2669347 A CA2669347 A CA 2669347A CA 2669347 A1 CA2669347 A1 CA 2669347A1
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- Prior art keywords
- gaa
- human
- fusion protein
- targeting domain
- mannose
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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| US60/879,255 | 2007-01-05 | ||
| US90018707P | 2007-02-07 | 2007-02-07 | |
| US60/900,187 | 2007-02-07 | ||
| PCT/US2007/023881 WO2008063511A2 (en) | 2006-11-13 | 2007-11-13 | Methods for treating pompe disease |
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| JP (1) | JP2010509344A (enExample) |
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| IL (1) | IL198692A0 (enExample) |
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| ES2572148T3 (es) | 2005-05-17 | 2016-05-30 | Amicus Therapeutics Inc | Un método para el tratamiento de la enfermedad de Pompe usando 1-desoxinojirimicina y derivados |
| US8536148B2 (en) | 2009-09-04 | 2013-09-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Disabling autophagy as a treatment for lysosomal storage diseases |
| WO2012061597A1 (en) * | 2010-11-03 | 2012-05-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institutes Of Health | Alpha-glucosidase binders and methods of their use |
| PE20140617A1 (es) * | 2011-04-22 | 2014-05-28 | Genzyme Corp | Alfa glucosidasa acida modificada con procesamiento acelerado |
| KR20140135222A (ko) | 2012-03-07 | 2014-11-25 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 폼페병의 치료를 위한 고농도 알파-글루코시다제 조성물 |
| WO2014130723A1 (en) * | 2013-02-20 | 2014-08-28 | Valerion Therapeutics, Llc | Methods and compositions for treatment of pompe disease |
| DK3201320T5 (da) | 2014-09-30 | 2024-10-14 | Amicus Therapeutics Inc | Højpotent sur alfa-glucosidase med forbedrede carbohydrater |
| MX394968B (es) | 2015-12-30 | 2025-03-24 | Amicus Therapeutics Inc | Alfa-glucosidasa con mayor cantidad de acido para el tratamiento de la enfermedad de pompe. |
| CA3019128A1 (en) | 2016-03-30 | 2017-10-05 | Amicus Therapeutics, Inc. | Formulations comprising recombinant acid alpha-glucosidase |
| KR102343162B1 (ko) | 2016-03-30 | 2021-12-23 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 고 m6p 재조합 단백질의 선택 방법 |
| SMT202300187T1 (it) | 2017-05-15 | 2023-07-20 | Amicus Therapeutics Inc | Alfa-glucosidasi acida umana ricombinante |
| CN110809583A (zh) | 2017-06-07 | 2020-02-18 | 瑞泽恩制药公司 | 用于内化酶的组合物和方法 |
| KR20200118151A (ko) | 2018-02-07 | 2020-10-14 | 리제너론 파마슈티칼스 인코포레이티드 | 치료 단백질 전달을 위한 방법 및 조성물 |
| BR112020021962A2 (pt) | 2018-04-30 | 2021-01-26 | Amicus Therapeutics, Inc. | construtos para terapia gênica e métodos de uso |
| MX2020012350A (es) | 2018-05-17 | 2021-01-29 | Regeneron Pharma | Anticuerpos anti-cd63, conjugados y usos de estos. |
| EP3863663A2 (en) | 2018-10-10 | 2021-08-18 | Amicus Therapeutics, Inc. | Disulfide bond stabilized polypeptide compositions and methods of use |
| BR112021021720A2 (pt) * | 2019-04-30 | 2021-12-28 | Univ Pennsylvania | Composições úteis para tratamento de doença de pompe |
| EP3871687A1 (en) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzyme replacement therapy for treating pompe disease |
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- 2007-11-13 AU AU2007322123A patent/AU2007322123A1/en not_active Abandoned
- 2007-11-13 US US11/985,360 patent/US20090117091A1/en not_active Abandoned
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- 2007-11-13 EP EP07867437A patent/EP2099523A2/en not_active Withdrawn
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| WO2008063511A3 (en) | 2009-04-09 |
| WO2008063511A2 (en) | 2008-05-29 |
| JP2010509344A (ja) | 2010-03-25 |
| EP2099523A2 (en) | 2009-09-16 |
| AU2007322123A1 (en) | 2008-05-29 |
| US20120093794A1 (en) | 2012-04-19 |
| US20090117091A1 (en) | 2009-05-07 |
| IL198692A0 (en) | 2011-07-31 |
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