CA2665616A1 - Effective delivery of cross-species a3 adenosine-receptor antagonists toreduce intraocular pressure - Google Patents
Effective delivery of cross-species a3 adenosine-receptor antagonists toreduce intraocular pressure Download PDFInfo
- Publication number
- CA2665616A1 CA2665616A1 CA002665616A CA2665616A CA2665616A1 CA 2665616 A1 CA2665616 A1 CA 2665616A1 CA 002665616 A CA002665616 A CA 002665616A CA 2665616 A CA2665616 A CA 2665616A CA 2665616 A1 CA2665616 A1 CA 2665616A1
- Authority
- CA
- Canada
- Prior art keywords
- mrs
- intraocular pressure
- eye
- iop
- adenosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85017506P | 2006-10-06 | 2006-10-06 | |
| US60/850,175 | 2006-10-06 | ||
| PCT/US2007/021409 WO2008045330A2 (en) | 2006-10-06 | 2007-10-05 | Effective delivery of cross-species a3 adenosine-receptor antagonists to reduce intraocular pressure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2665616A1 true CA2665616A1 (en) | 2008-04-17 |
Family
ID=39283379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002665616A Abandoned CA2665616A1 (en) | 2006-10-06 | 2007-10-05 | Effective delivery of cross-species a3 adenosine-receptor antagonists toreduce intraocular pressure |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090258836A1 (https=) |
| EP (1) | EP2076267A4 (https=) |
| JP (1) | JP2010505848A (https=) |
| AU (1) | AU2007307157A1 (https=) |
| BR (1) | BRPI0715318A2 (https=) |
| CA (1) | CA2665616A1 (https=) |
| MX (1) | MX2009003750A (https=) |
| WO (1) | WO2008045330A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG182285A1 (en) | 2010-01-11 | 2012-08-30 | Inotek Pharmaceuticals Corp | Combination, kit and method of reducing intraocular pressure |
| EA201290958A1 (ru) * | 2010-03-26 | 2013-04-30 | Инотек Фармасьютикалз Корпорейшн | Способ снижения внутриглазного давления у людей с применением n6-циклопентиладенозина (cpa), производных cpa или их пролекарств |
| BR112014018413A8 (pt) | 2012-01-26 | 2017-07-11 | Inotek Pharmaceuticals Corp | Polimorfos anidros de nitrato de metila [(2r,3s,4r,5r)-5-(6-(ciclopentilamino)-9h-purin-9-il)-3,4-diidroxitetraidrofuran-2-il)] e processos de preparação do mesmo |
| CA2903114A1 (en) | 2013-03-15 | 2014-09-25 | Inotek Pharmaceuticals Corporation | Ophthalmic formulations |
| ES2578363B1 (es) | 2015-01-22 | 2017-01-31 | Palobiofarma, S.L. | Moduladores de los receptores A3 de adenosina |
| HK1254892A1 (zh) | 2016-01-14 | 2019-08-02 | 韩德株式会社 | 拮抗a3腺苷受体的化合物、其制备方法、及其医学用途 |
| ES2676535B1 (es) | 2017-01-20 | 2019-04-29 | Palobiofarma Sl | Moduladores de los receptores a3 de adenosina |
| KR101805400B1 (ko) | 2017-03-21 | 2017-12-07 | 퓨쳐메디신 주식회사 | 아데노신 유도체를 포함하는 녹내장 예방 및 치료용 약학적 조성물 |
| CN109666053A (zh) * | 2017-10-16 | 2019-04-23 | 张家口华健致远生物科技有限公司 | 一种a3腺苷受体激动剂及其用途 |
| KR102007640B1 (ko) * | 2017-11-29 | 2019-08-07 | 퓨쳐메디신 주식회사 | 아데노신 유도체를 포함하는 망막 질환 또는 시신경 질환 예방 및 치료용 약학적 조성물 |
| US11395597B2 (en) * | 2018-06-26 | 2022-07-26 | General Electric Company | System and method for evaluating blood flow in a vessel |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2244774C (en) * | 1996-01-29 | 2006-10-17 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Dihydropyridine derivatives, their preparation and their use as adenosine receptor antagonists |
| ATE290910T1 (de) * | 1998-07-16 | 2005-04-15 | Univ Pennsylvania | Verwendung von a3-adenosine antagonisten zur herstellung eines arzneimittels zur senkung des augeninnendrucks |
| IL133680A0 (en) * | 1999-09-10 | 2001-04-30 | Can Fite Technologies Ltd | Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist |
-
2007
- 2007-10-05 JP JP2009531464A patent/JP2010505848A/ja active Pending
- 2007-10-05 WO PCT/US2007/021409 patent/WO2008045330A2/en not_active Ceased
- 2007-10-05 AU AU2007307157A patent/AU2007307157A1/en not_active Abandoned
- 2007-10-05 BR BRPI0715318-0A patent/BRPI0715318A2/pt not_active IP Right Cessation
- 2007-10-05 EP EP07852549.0A patent/EP2076267A4/en not_active Withdrawn
- 2007-10-05 CA CA002665616A patent/CA2665616A1/en not_active Abandoned
- 2007-10-05 MX MX2009003750A patent/MX2009003750A/es active IP Right Grant
-
2009
- 2009-04-06 US US12/419,062 patent/US20090258836A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007307157A1 (en) | 2008-04-17 |
| EP2076267A4 (en) | 2013-07-31 |
| BRPI0715318A2 (pt) | 2013-07-16 |
| EP2076267A2 (en) | 2009-07-08 |
| WO2008045330A3 (en) | 2008-06-26 |
| JP2010505848A (ja) | 2010-02-25 |
| WO2008045330A2 (en) | 2008-04-17 |
| MX2009003750A (es) | 2009-06-18 |
| US20090258836A1 (en) | 2009-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20141007 |