CA2664133C - A method for correcting a spectral image for optical aberrations using software - Google Patents

A method for correcting a spectral image for optical aberrations using software Download PDF

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Publication number
CA2664133C
CA2664133C CA2664133A CA2664133A CA2664133C CA 2664133 C CA2664133 C CA 2664133C CA 2664133 A CA2664133 A CA 2664133A CA 2664133 A CA2664133 A CA 2664133A CA 2664133 C CA2664133 C CA 2664133C
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CA
Canada
Prior art keywords
light
spectral image
intensity
wavelength
correcting
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CA2664133A
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English (en)
French (fr)
Other versions
CA2664133A1 (en
Inventor
James E. Smous
Mihailo V. Rebec
Michael P. Houlne
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Bayer Healthcare LLC
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Bayer Healthcare LLC
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Publication of CA2664133A1 publication Critical patent/CA2664133A1/en
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Publication of CA2664133C publication Critical patent/CA2664133C/en
Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14556—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases by fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6423—Spectral mapping, video display

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Optics & Photonics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Engineering & Computer Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
CA2664133A 2006-08-22 2007-08-17 A method for correcting a spectral image for optical aberrations using software Expired - Fee Related CA2664133C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83916606P 2006-08-22 2006-08-22
US60/839,166 2006-08-22
PCT/US2007/018234 WO2008024276A2 (en) 2006-08-22 2007-08-17 A method for correcting a spectral image for optical aberrations using software

Publications (2)

Publication Number Publication Date
CA2664133A1 CA2664133A1 (en) 2008-02-28
CA2664133C true CA2664133C (en) 2012-10-23

Family

ID=39047978

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2664133A Expired - Fee Related CA2664133C (en) 2006-08-22 2007-08-17 A method for correcting a spectral image for optical aberrations using software

Country Status (6)

Country Link
US (2) US7705980B2 (https=)
EP (1) EP2077748A2 (https=)
JP (2) JP5199256B2 (https=)
CA (1) CA2664133C (https=)
TW (1) TW200817666A (https=)
WO (1) WO2008024276A2 (https=)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8460243B2 (en) 2003-06-10 2013-06-11 Abbott Diabetes Care Inc. Glucose measuring module and insulin pump combination
US7722536B2 (en) 2003-07-15 2010-05-25 Abbott Diabetes Care Inc. Glucose measuring device integrated into a holster for a personal area network device
CA3090413C (en) 2004-06-04 2023-10-10 Abbott Diabetes Care Inc. Glucose monitoring and graphical representations in a data management system
US8452365B2 (en) * 2005-05-25 2013-05-28 Bayer Healthcare Llc Methods of using Raman spectral information in determining analyte concentrations
EP2077748A2 (en) * 2006-08-22 2009-07-15 Bayer Healthcare, LLC A method for correcting a spectral image for optical aberrations using software
CN102015020A (zh) * 2008-05-09 2011-04-13 休·贝克曼 用于诊断和治疗异常组织的医疗设备及其使用方法
US9202140B2 (en) * 2008-09-05 2015-12-01 Siemens Medical Solutions Usa, Inc. Quotient appearance manifold mapping for image classification
JP5424108B2 (ja) * 2008-11-18 2014-02-26 株式会社エス・テイ・ジャパン ラマンイメージング装置
WO2011041531A1 (en) 2009-09-30 2011-04-07 Abbott Diabetes Care Inc. Interconnect for on-body analyte monitoring device
GB201000179D0 (en) 2010-01-07 2010-02-24 Rsp Systems As Apparatus for non-invasive in vivo measurement by raman spectroscopy
JP2012122851A (ja) * 2010-12-08 2012-06-28 St Japan Inc ラマン分析装置
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
US8891073B2 (en) * 2011-07-14 2014-11-18 Battelle Energy Alliance, Llc Apparatus, system, and method for laser-induced breakdown spectroscopy
US8861900B2 (en) 2012-02-23 2014-10-14 Corning Incorporated Probe optical assemblies and probes for optical coherence tomography
US8967885B2 (en) 2012-02-23 2015-03-03 Corning Incorporated Stub lens assemblies for use in optical coherence tomography systems
US8857220B2 (en) 2012-02-23 2014-10-14 Corning Incorporated Methods of making a stub lens element and assemblies using same for optical coherence tomography applications
US9036966B2 (en) 2012-03-28 2015-05-19 Corning Incorporated Monolithic beam-shaping optical systems and methods for an OCT probe
JP6488501B2 (ja) * 2013-09-11 2019-03-27 株式会社分光科学研究所 計測方法及び計測装置
JP6316064B2 (ja) * 2014-03-31 2018-04-25 株式会社日立ハイテクサイエンス Ｉｃｐ発光分光分析装置
WO2015174819A2 (en) * 2014-05-16 2015-11-19 Mimos Berhad Method for producing narrow spectral linewidths
FR3035716B1 (fr) * 2015-04-30 2019-06-21 Biomerieux Machine et procede pour la detection automatisee in vitro d'analytes mettant en oeuvre une decomposition spectrale chromatique d'une reponse optique
DE102018205400B4 (de) 2018-04-10 2026-03-26 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Spektralanalysesystem, mobiles gerät mit einem spektralanalysesystem, ein verfahren zur bestimmung einer korrekturfunktion zur abbildungskorrektur eines durch ein spektralanalysesystem aufgenommenen spektrums und computerprogramm
KR102655740B1 (ko) * 2018-06-20 2024-04-05 삼성전자주식회사 스펙트럼 이미지 보정 장치 및 방법과, 대상체의 성분 분석 장치
US11740128B2 (en) * 2019-07-24 2023-08-29 Sanguis Corporation System and method for non-invasive measurement of analytes in vivo
CN114910416B (zh) * 2022-04-28 2024-07-30 彩谱科技(浙江)有限公司 一种高光谱颜色测量定标系统及定标方法
CN121347463A (zh) * 2024-07-16 2026-01-16 广州睿芯微电子有限公司 利用紫外光进行荧光光谱数据采集的方法、系统及介质

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645340A (en) 1983-06-01 1987-02-24 Boston University Optically reflective sphere for efficient collection of Raman scattered light
GB2141554A (en) 1983-06-15 1984-12-19 Philips Electronic Associated A slit imaging system using two concave mirrors
EP0573535B1 (en) 1991-02-26 2000-12-27 Massachusetts Institute Of Technology Systems and methods of molecular spectroscopy to provide for the diagnosis of tissue
US5404869A (en) 1992-04-16 1995-04-11 Tir Technologies, Inc. Faceted totally internally reflecting lens with individually curved faces on facets
US5560356A (en) 1994-02-23 1996-10-01 Vitrophage, Inc. Diagnostic system and method using an implanted reflective device
US5615673A (en) 1995-03-27 1997-04-01 Massachusetts Institute Of Technology Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes
JP3792273B2 (ja) * 1995-06-30 2006-07-05 株式会社島津製作所 分光測定装置
JPH09184809A (ja) 1995-12-30 1997-07-15 Koyo Ozaki 散乱光測定装置
US5923482A (en) 1997-03-14 1999-07-13 Waters Investments Limited Changing astigmatism in an optical system
EP1037553B1 (en) 1997-11-12 2007-01-24 Lightouch Medical, Inc. Method for non-invasive measurement of an analyte
US6070093A (en) 1997-12-02 2000-05-30 Abbott Laboratories Multiplex sensor and method of use
US6051835A (en) * 1998-01-07 2000-04-18 Bio-Rad Laboratories, Inc. Spectral imaging apparatus and methodology
ES2224602T3 (es) 1998-01-27 2005-03-01 Lightouch Medical, Inc. Metodo y dispositivo de modulacion de tejido.
US6560478B1 (en) 1998-03-16 2003-05-06 The Research Foundation Of City University Of New York Method and system for examining biological materials using low power CW excitation Raman spectroscopy
EP1073366B1 (en) 1998-04-24 2004-06-23 Lightouch Medical, Inc. Apparatus and method for thermal tissue modulation
US6389306B1 (en) 1998-04-24 2002-05-14 Lightouch Medical, Inc. Method for determining lipid and protein content of tissue
WO2000001295A1 (en) 1998-07-07 2000-01-13 Lightouch Medical, Inc. Tissue modulation process for quantitative noninvasive in vivo spectroscopic analysis of tissues
US6332092B1 (en) 1998-07-08 2001-12-18 Lifespex, Incorporated Optical probe having and methods for uniform light irradiation and/or light collection over a volume
US6615061B1 (en) 1998-11-23 2003-09-02 Abbott Laboratories Optical sensor having a selectable sampling distance for determination of analytes
US6352502B1 (en) 1998-12-03 2002-03-05 Lightouch Medical, Inc. Methods for obtaining enhanced spectroscopic information from living tissue, noninvasive assessment of skin condition and detection of skin abnormalities
US6503478B2 (en) 1999-01-13 2003-01-07 Lightouch Medical, Inc. Chemically specific imaging of tissue
US6167290A (en) 1999-02-03 2000-12-26 Bayspec, Inc. Method and apparatus of non-invasive measurement of human/animal blood glucose and other metabolites
US6486948B1 (en) 1999-09-14 2002-11-26 Haishan Zeng Apparatus and methods relating to high speed Raman spectroscopy
US6574490B2 (en) 2001-04-11 2003-06-03 Rio Grande Medical Technologies, Inc. System for non-invasive measurement of glucose in humans
US6983176B2 (en) 2001-04-11 2006-01-03 Rio Grande Medical Technologies, Inc. Optically similar reference samples and related methods for multivariate calibration models used in optical spectroscopy
US6561648B2 (en) * 2001-05-23 2003-05-13 David E. Thomas System and method for reconstruction of aberrated wavefronts
JP4494779B2 (ja) 2001-08-02 2010-06-30 グルコビスタ・エルエルシー 非侵襲グルコース計測器
WO2003011764A2 (en) * 2001-08-03 2003-02-13 Volker Westphal Real-time imaging system and method
US6636305B2 (en) 2001-09-13 2003-10-21 New Chromex, Inc. Apparatus and method for producing a substantially straight instrument image
US7226166B2 (en) * 2001-11-13 2007-06-05 Philadelphia Retina Endowment Fund Optimizing the properties of electromagnetic energy in a medium using stochastic parallel perturbation gradient descent optimization adaptive optics
US6975891B2 (en) 2001-12-21 2005-12-13 Nir Diagnostics Inc. Raman spectroscopic system with integrating cavity
WO2004023125A2 (en) 2002-09-05 2004-03-18 Pendragon Medical Ltd. Impedance spectroscopy based systems and methods
WO2004064627A1 (en) 2003-01-21 2004-08-05 British Columbia Cancer Agency In vivo raman endoscopic probe and methods of use
WO2004082474A1 (en) * 2003-03-18 2004-09-30 Koninklijke Philips Electronics N.V. Analysis of a composition with monitoring
US20050043597A1 (en) 2003-07-31 2005-02-24 Skymoon Research And Development, Llc Optical vivo probe of analyte concentration within the sterile matrix under the human nail
US7046359B2 (en) * 2004-06-30 2006-05-16 Chemimage Corporation System and method for dynamic chemical imaging
JP4512465B2 (ja) * 2004-10-13 2010-07-28 株式会社日立ハイテクノロジーズ 電気泳動装置
US8452365B2 (en) 2005-05-25 2013-05-28 Bayer Healthcare Llc Methods of using Raman spectral information in determining analyte concentrations
WO2007040589A1 (en) * 2005-09-16 2007-04-12 The Regents Of The University Of Michigan Method and system for measuring sub-surface composition of a sample
US7603151B2 (en) 2006-08-22 2009-10-13 Bayer Healthcare Llc Non-invasive methods of using spectral information in determining analyte concentrations
EP2077748A2 (en) * 2006-08-22 2009-07-15 Bayer Healthcare, LLC A method for correcting a spectral image for optical aberrations using software

Also Published As

Publication number Publication date
JP5199256B2 (ja) 2013-05-15
TW200817666A (en) 2008-04-16
US7944556B2 (en) 2011-05-17
US20100226549A1 (en) 2010-09-09
JP2013101142A (ja) 2013-05-23
WO2008024276A2 (en) 2008-02-28
US7705980B2 (en) 2010-04-27
US20080059100A1 (en) 2008-03-06
CA2664133A1 (en) 2008-02-28
JP2010501251A (ja) 2010-01-21
WO2008024276A3 (en) 2008-05-08
EP2077748A2 (en) 2009-07-15

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