CA2663005A1 - System and method for continuous detection of an analyte in bloodstream - Google Patents
System and method for continuous detection of an analyte in bloodstream Download PDFInfo
- Publication number
- CA2663005A1 CA2663005A1 CA002663005A CA2663005A CA2663005A1 CA 2663005 A1 CA2663005 A1 CA 2663005A1 CA 002663005 A CA002663005 A CA 002663005A CA 2663005 A CA2663005 A CA 2663005A CA 2663005 A1 CA2663005 A1 CA 2663005A1
- Authority
- CA
- Canada
- Prior art keywords
- biosensor
- blood
- analyte
- blood vessel
- change
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 239000012491 analyte Substances 0.000 title claims abstract description 78
- 238000000034 method Methods 0.000 title claims abstract description 26
- 238000001514 detection method Methods 0.000 title description 7
- 239000008280 blood Substances 0.000 claims abstract description 65
- 210000004369 blood Anatomy 0.000 claims abstract description 65
- 230000008859 change Effects 0.000 claims abstract description 52
- 210000004204 blood vessel Anatomy 0.000 claims abstract description 34
- 239000000463 material Substances 0.000 claims abstract description 27
- 238000003556 assay Methods 0.000 claims abstract description 16
- 238000004891 communication Methods 0.000 claims abstract description 16
- 239000012530 fluid Substances 0.000 claims abstract description 15
- 238000010223 real-time analysis Methods 0.000 claims abstract description 7
- 230000000747 cardiac effect Effects 0.000 claims description 5
- 238000004364 calculation method Methods 0.000 claims description 4
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000013078 crystal Substances 0.000 claims description 4
- 108010088751 Albumins Proteins 0.000 claims description 2
- 102000009027 Albumins Human genes 0.000 claims description 2
- 108010074051 C-Reactive Protein Proteins 0.000 claims description 2
- 102100032752 C-reactive protein Human genes 0.000 claims description 2
- 102000004420 Creatine Kinase Human genes 0.000 claims description 2
- 108010042126 Creatine kinase Proteins 0.000 claims description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 2
- 108010044467 Isoenzymes Proteins 0.000 claims description 2
- 108090000235 Myeloperoxidases Proteins 0.000 claims description 2
- 102000003896 Myeloperoxidases Human genes 0.000 claims description 2
- 102100030856 Myoglobin Human genes 0.000 claims description 2
- 108010062374 Myoglobin Proteins 0.000 claims description 2
- 229940109239 creatinine Drugs 0.000 claims description 2
- 239000008103 glucose Substances 0.000 claims description 2
- 230000004044 response Effects 0.000 claims description 2
- 230000000007 visual effect Effects 0.000 claims 3
- 239000000523 sample Substances 0.000 description 18
- 239000003795 chemical substances by application Substances 0.000 description 10
- 230000017531 blood circulation Effects 0.000 description 4
- 238000004458 analytical method Methods 0.000 description 3
- 230000005284 excitation Effects 0.000 description 3
- 208000010125 myocardial infarction Diseases 0.000 description 3
- 206010061216 Infarction Diseases 0.000 description 2
- 238000000151 deposition Methods 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 230000007574 infarction Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010049119 Emotional distress Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 206010000891 acute myocardial infarction Diseases 0.000 description 1
- 238000004159 blood analysis Methods 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000000099 in vitro assay Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000000737 periodic effect Effects 0.000 description 1
- 239000010453 quartz Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N silicon dioxide Inorganic materials O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6848—Needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0204—Acoustic sensors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Emergency Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/528,907 US8092384B2 (en) | 2006-09-28 | 2006-09-28 | System and method for continuous detection of an analyte in bloodstream |
| US11/528,907 | 2006-09-28 | ||
| PCT/US2007/020843 WO2008042217A1 (en) | 2006-09-28 | 2007-09-27 | System and method for continuous detection of an analyte in bloodstream |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2663005A1 true CA2663005A1 (en) | 2008-04-10 |
Family
ID=39268753
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002663005A Abandoned CA2663005A1 (en) | 2006-09-28 | 2007-09-27 | System and method for continuous detection of an analyte in bloodstream |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8092384B2 (enExample) |
| EP (1) | EP2067029A1 (enExample) |
| JP (1) | JP2010504819A (enExample) |
| AU (1) | AU2007305424A1 (enExample) |
| CA (1) | CA2663005A1 (enExample) |
| MX (1) | MX2009003066A (enExample) |
| WO (1) | WO2008042217A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090326344A1 (en) * | 2008-06-27 | 2009-12-31 | Tyco Healthcare Group Lp | System and Method for Optical Continuous Detection of an Analyte In Bloodstream |
| DE102010011560B4 (de) * | 2010-03-16 | 2021-09-16 | Gilupi Gmbh | Biodetektor |
| KR101647507B1 (ko) * | 2014-10-20 | 2016-08-10 | 건국대학교 글로컬산학협력단 | 정전용량 기반의 혈관삽입형 바이오센서를 이용한 심혈관 질환 진단 데이터 획득 시스템 및 방법 |
| WO2018017196A1 (en) * | 2016-07-18 | 2018-01-25 | Siemens Healthcare Diagnostics Inc. | Biofouling prevention of wearable sensors and methods of use and calibration related thereto |
| WO2018173467A1 (ja) * | 2017-03-21 | 2018-09-27 | テルモ株式会社 | センサ、計測装置、及びセンサの製造方法 |
| WO2024014634A1 (ko) * | 2022-07-13 | 2024-01-18 | 주식회사 뮨 | 혈액 진단기능을 갖는 폐쇄채혈 자동화 장치 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5000185A (en) * | 1986-02-28 | 1991-03-19 | Cardiovascular Imaging Systems, Inc. | Method for intravascular two-dimensional ultrasonography and recanalization |
| US4794931A (en) * | 1986-02-28 | 1989-01-03 | Cardiovascular Imaging Systems, Inc. | Catheter apparatus, system and method for intravascular two-dimensional ultrasonography |
| US5501986A (en) * | 1988-04-06 | 1996-03-26 | E. I. Du Pont De Nemours And Company | Piezoelectric specific binding assay with mass amplified reagents |
| US4999284A (en) * | 1988-04-06 | 1991-03-12 | E. I. Du Pont De Nemours And Company | Enzymatically amplified piezoelectric specific binding assay |
| US5139328A (en) * | 1989-05-24 | 1992-08-18 | Separation Technology, Inc. | Noncontact hematocrit reader apparatus and method |
| WO1991005261A1 (en) * | 1989-10-04 | 1991-04-18 | E.I. Du Pont De Nemours And Company | Assay method for biological target complexes on the surface of a biosensor |
| US4963351A (en) * | 1989-12-26 | 1990-10-16 | Bhn Associates | Shaving aid |
| US5113585A (en) * | 1990-09-28 | 1992-05-19 | The Gillette Company | Shaving system |
| US5658956A (en) * | 1991-03-01 | 1997-08-19 | Warner-Lambert Company | Bioadhesive-wound healing compositions and methods for preparing and using same |
| US5692302A (en) * | 1991-03-01 | 1997-12-02 | Warner-Lambert Company | Razor cartridges comprising wound healing compositions and methods for preparing and using same |
| US5335658A (en) * | 1992-06-29 | 1994-08-09 | Minnesota Mining And Manufacturing Company | Intravascular blood parameter sensing system |
| US5503982A (en) * | 1993-09-30 | 1996-04-02 | Research Corporation Technologies, Inc. | Detection of an acute myocardial infarction in a patient |
| US5431906A (en) * | 1994-01-12 | 1995-07-11 | Joseph Briana | Solid shaving compositions |
| US5705399A (en) * | 1994-05-20 | 1998-01-06 | The Cooper Union For Advancement Of Science And Art | Sensor and method for detecting predetermined chemical species in solution |
| US6594904B1 (en) * | 1994-07-01 | 2003-07-22 | The Gillette Company | Shaving system |
| WO1996001171A1 (en) * | 1994-07-01 | 1996-01-18 | The Gillette Company | Skin engaging member for razor blade assembly |
| JPH0875629A (ja) * | 1994-09-09 | 1996-03-22 | Nippon Steel Corp | 流体中吸着物量連続測定素子及び材料層コーティング方法 |
| US5795725A (en) * | 1995-04-18 | 1998-08-18 | Biosite Diagnostics Incorporated | Methods for the assay of troponin I and T and selection of antibodies for use in immunoassays |
| US5814525A (en) * | 1996-01-25 | 1998-09-29 | Sandia Corporation | Piezoelectric biosensor with a ladder polymer substrate coating |
| US5730144A (en) * | 1996-07-10 | 1998-03-24 | The United States Of America As Represented By The Secretary Of The Navy | Method and apparatus for predicting the efficacy of cardioversion |
| US5956848A (en) * | 1997-02-27 | 1999-09-28 | The Gillette Company | Shaving system |
| US6140740A (en) * | 1997-12-30 | 2000-10-31 | Remon Medical Technologies, Ltd. | Piezoelectric transducer |
| US6486588B2 (en) * | 1997-12-30 | 2002-11-26 | Remon Medical Technologies Ltd | Acoustic biosensor for monitoring physiological conditions in a body implantation site |
| US6200532B1 (en) * | 1998-11-20 | 2001-03-13 | Akzo Nobel Nv | Devices and method for performing blood coagulation assays by piezoelectric sensing |
| NL1012223C2 (nl) * | 1999-06-03 | 2000-12-06 | Martil Instr B V | Hartgangmaker alsmede gangmakereenheid en elektrische draad daarvoor. |
| US6692437B2 (en) * | 1999-11-12 | 2004-02-17 | Rheologics, Inc. | Method for determining the viscosity of an adulterated blood sample over plural shear rates |
| US6442413B1 (en) * | 2000-05-15 | 2002-08-27 | James H. Silver | Implantable sensor |
| US6848295B2 (en) * | 2002-04-17 | 2005-02-01 | Wayne State University | Acoustic wave sensor apparatus, method and system using wide bandgap materials |
| SE0201874D0 (sv) * | 2002-06-19 | 2002-06-19 | Biosensor Applications Sweden Ab Publ | Coated metal surface on solid support for displacement reactions |
| US7111500B2 (en) * | 2002-12-26 | 2006-09-26 | Ulvac Inc. | Analysis method using piezoelectric resonator |
| US7857761B2 (en) * | 2003-04-16 | 2010-12-28 | Drexel University | Acoustic blood analyzer for assessing blood properties |
| US7415883B2 (en) * | 2004-06-28 | 2008-08-26 | Zuli Holdings Ltd | Method for protecting resonating sensors and open protected resonating sensors |
| US8165651B2 (en) * | 2004-02-09 | 2012-04-24 | Abbott Diabetes Care Inc. | Analyte sensor, and associated system and method employing a catalytic agent |
| EP1843696A4 (en) * | 2005-01-04 | 2010-01-06 | Dune Medical Devices Ltd | ENDOSCOPIC SYSTEM FOR PROCEDURES IN VIVO |
-
2006
- 2006-09-28 US US11/528,907 patent/US8092384B2/en active Active
-
2007
- 2007-09-27 CA CA002663005A patent/CA2663005A1/en not_active Abandoned
- 2007-09-27 AU AU2007305424A patent/AU2007305424A1/en not_active Abandoned
- 2007-09-27 EP EP07838927A patent/EP2067029A1/en not_active Withdrawn
- 2007-09-27 JP JP2009530412A patent/JP2010504819A/ja active Pending
- 2007-09-27 MX MX2009003066A patent/MX2009003066A/es active IP Right Grant
- 2007-09-27 WO PCT/US2007/020843 patent/WO2008042217A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| MX2009003066A (es) | 2009-04-02 |
| WO2008042217A8 (en) | 2009-06-11 |
| JP2010504819A (ja) | 2010-02-18 |
| AU2007305424A1 (en) | 2008-04-10 |
| US20080086037A1 (en) | 2008-04-10 |
| EP2067029A1 (en) | 2009-06-10 |
| US8092384B2 (en) | 2012-01-10 |
| WO2008042217A1 (en) | 2008-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20140929 |