CA2656910C - Anti-cancer therapy comprising an h2-blocker, at least one antiinflammatory agent and a cytotoxic agent - Google Patents
Anti-cancer therapy comprising an h2-blocker, at least one antiinflammatory agent and a cytotoxic agent Download PDFInfo
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- CA2656910C CA2656910C CA2656910A CA2656910A CA2656910C CA 2656910 C CA2656910 C CA 2656910C CA 2656910 A CA2656910 A CA 2656910A CA 2656910 A CA2656910 A CA 2656910A CA 2656910 C CA2656910 C CA 2656910C
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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Landscapes
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- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US81916406P | 2006-07-07 | 2006-07-07 | |
| US60/819,164 | 2006-07-07 | ||
| US88010707P | 2007-01-12 | 2007-01-12 | |
| US60/880,107 | 2007-01-12 | ||
| PCT/IL2007/000836 WO2008004231A1 (en) | 2006-07-07 | 2007-07-04 | Anti-cancer therapy comprising an h2-blocker, at least one antiinflammatory agent and a cytotoxic agent |
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| CA2851079A1 (en) | 2005-04-15 | 2006-10-26 | Albert Einstein College Of Medicine Of Yeshiva University | Vitamin k for prevention and treatment of skin rash secondary to anti-egfr therapy |
| EP2043685B1 (en) | 2006-07-03 | 2015-12-23 | Genmab A/S | Prevention of rash in patients undergoing anti-egfr therapy |
| US8815953B2 (en) | 2008-03-13 | 2014-08-26 | Spectrum Pharmaceuticals, Inc. | Formulations of vitamin K analogs for topical use |
| EP2364140A1 (en) * | 2008-11-28 | 2011-09-14 | Advance Holdings Limited | Pharmaceutical formulation comprising diclofenac and a hydroxy fatty acid polyoxyalkylene ester |
| US10485780B2 (en) | 2011-03-14 | 2019-11-26 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the treatment of proliferative disorders |
| US20140228423A1 (en) * | 2011-06-01 | 2014-08-14 | Baylor College Of Medicine | Biomarkers and therapy for cancer |
| CN104144701A (zh) * | 2012-01-09 | 2014-11-12 | 蒂尔坦制药有限公司 | 用于治疗癌症的组合疗法 |
| CN105792823B (zh) * | 2013-11-01 | 2019-11-12 | 皮特尼制药股份有限公司 | 治疗恶性肿瘤的药物组合 |
| US9968579B2 (en) | 2014-07-17 | 2018-05-15 | Beth Isreal Deaconess Medical Center, Inc. | ATRA for modulating Pin1 activity and stability |
| WO2016166761A1 (en) * | 2015-04-14 | 2016-10-20 | Tiltan Pharma Ltd. | Combination therapies and uses thereof in the treatment of cancer |
| WO2018069924A1 (en) | 2016-10-10 | 2018-04-19 | Tiltan Pharma Ltd. | Non-cytotoxic combination therapies and uses thereof in the treatment of cancer |
| TR201717134A2 (tr) * | 2016-12-07 | 2018-07-23 | Imuneks Farma Ilac Sanayi Ve Ticaret Anonim Sirketi | Ağrı Ve Enflamasyonun Hızlı Tedavisi İçin Diklofenak Ve H2 Reseptör Antagonistlerinin Çabuk Salımlı Oral Kombinasyonları |
| TR201718099A2 (tr) * | 2017-11-16 | 2019-06-21 | Mehmet Nevzat Pisak | Ağri ve enflamasyonun tedavi̇si̇ i̇çi̇n di̇klofenak, h2 reseptör antagoni̇stleri̇ ve alkali̇ metal bi̇karbonatlarindan olusan kombi̇nasyonlar |
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| CA2128103C (en) * | 1992-01-16 | 2004-12-28 | Kapil Mehta | Formulation and use of carotenoids in treatment of cancer |
| CA2086874E (en) * | 1992-08-03 | 2000-01-04 | Renzo Mauro Canetta | Methods for administration of taxol |
| JPH11228409A (ja) * | 1997-09-23 | 1999-08-24 | Smith Kline Beecham Seiyaku Kk | 新規癌治療 |
| US7182942B2 (en) * | 2000-10-27 | 2007-02-27 | Irx Therapeutics, Inc. | Vaccine immunotherapy for immune suppressed patients |
| US20030158118A1 (en) | 2001-11-26 | 2003-08-21 | Weidner Morten Sloth | Combination of cimetidine and cysteine derivatives for treating cancer |
| WO2003061566A2 (en) | 2002-01-24 | 2003-07-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Anti-cancer combination and use thereof |
| AU2005213472A1 (en) * | 2004-02-10 | 2005-08-25 | Santarus, Inc. | Combination of proton pump inhibitor, buffering agent, and nonsteroidal anti-inflammatory agent |
| US20090010887A1 (en) | 2004-10-06 | 2009-01-08 | Ben-Sasson Shmuel A | Method and composition for enhancing anti-angiogenic therapy |
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Also Published As
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| ES2414708T3 (es) | 2013-07-22 |
| EP2043659B1 (en) | 2013-04-03 |
| AU2007270686A1 (en) | 2008-01-10 |
| AU2007270686B2 (en) | 2011-05-26 |
| US20090318391A1 (en) | 2009-12-24 |
| CN101511372A (zh) | 2009-08-19 |
| EP2043659A1 (en) | 2009-04-08 |
| JP2009542623A (ja) | 2009-12-03 |
| WO2008004231A1 (en) | 2008-01-10 |
| CA2656910A1 (en) | 2008-01-10 |
| US7838513B2 (en) | 2010-11-23 |
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