CA2651212A1 - Hydrolytically-resistant boron-containing therapeutics and methods of use - Google Patents

Hydrolytically-resistant boron-containing therapeutics and methods of use Download PDF

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Publication number
CA2651212A1
CA2651212A1 CA002651212A CA2651212A CA2651212A1 CA 2651212 A1 CA2651212 A1 CA 2651212A1 CA 002651212 A CA002651212 A CA 002651212A CA 2651212 A CA2651212 A CA 2651212A CA 2651212 A1 CA2651212 A1 CA 2651212A1
Authority
CA
Canada
Prior art keywords
substituted
unsubstituted
alkyl
compound
member selected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002651212A
Other languages
English (en)
French (fr)
Inventor
Ving Lee
Jacob J. Plattner
Stephen J. Benkovic
Stephen J. Baker
Kirk R. Maples
Carolyn Bellinger-Kawahara
Tsutomu Akama
Yong-Kang Zhang
Vittorio A. Sauro
Rajeshwar Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anacor Pharmaceuticals LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2651212A1 publication Critical patent/CA2651212A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002651212A 2006-05-02 2007-05-02 Hydrolytically-resistant boron-containing therapeutics and methods of use Abandoned CA2651212A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81362306P 2006-05-02 2006-05-02
US60/813,623 2006-05-02
PCT/US2007/068079 WO2007131072A2 (en) 2006-05-02 2007-05-02 Hydrolytically-resistant boron-containing therapeutics and methods of use

Publications (1)

Publication Number Publication Date
CA2651212A1 true CA2651212A1 (en) 2007-11-15

Family

ID=38668534

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002651212A Abandoned CA2651212A1 (en) 2006-05-02 2007-05-02 Hydrolytically-resistant boron-containing therapeutics and methods of use

Country Status (6)

Country Link
US (1) US8106031B2 (https=)
EP (1) EP2015757A4 (https=)
JP (1) JP2009536660A (https=)
BR (1) BRPI0711155A2 (https=)
CA (1) CA2651212A1 (https=)
WO (1) WO2007131072A2 (https=)

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WO2010011354A2 (en) * 2008-07-25 2010-01-28 Innovation Biomedical Devices, Inc. Enchanced trans-keratin drug delivery
WO2010045503A1 (en) * 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents
AP4039A (en) * 2009-08-14 2017-02-28 Daitao Chen Boron-containing small molecules as antiprotozoal agents
WO2011094450A1 (en) 2010-01-27 2011-08-04 Anacor Pharmaceuticals, Inc Boron-containing small molecules
SI3251678T1 (sl) * 2010-09-07 2022-01-31 Anacor Pharmaceuticals, Inc. Derivati benzoksaborola za zdravljenje bakterijskih okužb
MX2014001833A (es) * 2011-08-17 2014-02-27 Glaxosmithkline Llc Metodos terapeuticos.
PH12014500385A1 (en) * 2011-08-19 2020-06-22 Glaxo Group Ltd Benzofuran compounds for the treatment of hepatitis c virus infections
JP6031122B2 (ja) * 2011-12-22 2016-11-24 ミクウルク ファーマシューティカルズ，インコーポレイテッド 抗微生物療法のための三環式ホウ素化合物
US9234048B2 (en) 2012-01-18 2016-01-12 Wisconsin Alumni Research Foundation Boronate-mediated delivery of molecules into cells
US9732101B2 (en) 2012-01-18 2017-08-15 Wisconsin Alumni Research Foundation Bioreversible boronates for delivery of molecules into cells
US8669207B1 (en) 2013-01-30 2014-03-11 Dow Agrosciences, Llc. Compounds and compositions
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
MA38319A1 (fr) * 2013-01-30 2016-08-31 Dow Agrosciences Llc Utilisation des benzoxaboroles à titre d'agents antimicrobiens volatils sur les viandes, les plantes, ou des parties de plantes
AU2014202928B1 (en) * 2013-06-05 2014-09-11 Agrofresh Inc. Compounds and compositions
EP3148551B1 (en) * 2014-05-12 2021-09-29 AgroFresh Inc. Volatile applications against pathogens
EP3164404B1 (en) 2014-07-01 2019-04-03 Daiichi Sankyo Company, Limited Tricyclic benzoxaboroles as antibacterial agents
DK3209319T3 (da) 2014-10-21 2021-10-04 Hexima Ltd En fremgangsmåde til behandling af svampeinfektioner
US9737075B2 (en) * 2015-04-09 2017-08-22 The Penn State Research Foundation Synergistic benzoxaborole-containing anti-fungicidal composition
WO2017024022A1 (en) * 2015-08-06 2017-02-09 The Penn State Research Foundation Benzoxaborole-containing coating resistant to cellulose-supportable fungus
RS64770B1 (sr) 2016-03-07 2023-11-30 Agrofresh Inc Sinergistički postupci upotrebe jedinjenja benzoksaborola i gasova za prezerviranje kao antimikrobnih agenasa za useve
US11857352B2 (en) 2016-09-06 2024-01-02 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
MA52337A (fr) 2017-03-01 2021-03-03 Anacor Pharmaceuticals Inc Nouveaux analogues d'oxaborole et utilisations de ces derniers
MX2020005464A (es) 2017-11-30 2020-12-03 Boragen Inc Compuestos de benzoxaborol y formulaciones de los mismos.
WO2020041200A1 (en) 2018-08-18 2020-02-27 Boragen Inc. Solid forms of substituted benzoxaborole and compositions thereof
KR102717210B1 (ko) * 2018-12-21 2024-10-15 삼성디스플레이 주식회사 유기 전계 발광 소자 및 유기 전계 발광 소자용 다환 화합물
CN110183477B (zh) * 2019-07-03 2022-03-04 石家庄诚志永华显示材料有限公司 有机电致发光化合物及其应用
AR120504A1 (es) 2019-11-22 2022-02-16 Agrofresh Inc Composición y método para tratar a plantas y partes de plantas con activos volátiles para el control de organismos de descomposición
MX2022009594A (es) 2020-02-05 2022-09-26 Agrofresh Inc Compuestos y composiciones antimicrobianos.
EP4204012A1 (en) 2020-08-31 2023-07-05 Pfizer Inc. Methods of protecting rna

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AU2823395A (en) 1994-06-07 1996-01-04 Sri International Novel compounds useful in modulating gene expression of retinoid responsive genes and/or having anti-ap-1 activity
GB9411587D0 (en) * 1994-06-09 1994-08-03 Zeneca Ltd Compound, composition and use
CA2225014A1 (en) 1997-12-16 1999-06-16 Peter Zoricak B-n heterocyclic ligands
WO2003033002A1 (en) * 2001-10-11 2003-04-24 Ono Pharmaceutical Co Intracellular calcium concentration increase inhibitors
BRPI0411582A (pt) * 2003-06-16 2006-08-08 Anacor Pharmaceuticals Inc substáncias terapêuticas contendo boro hidroliticamente resistentes e método de uso
GB0501944D0 (en) 2005-01-31 2005-03-09 Univ Cambridge Tech Compounds for use in chemical detection and/or quantitation
EP2343304B1 (en) * 2005-02-16 2015-06-10 Anacor Pharmaceuticals, Inc. Biocidal boronophthalide compounds
KR20080110984A (ko) * 2005-12-30 2008-12-22 아나코르 파마슈티칼스 인코포레이티드 보론함유 소분자
PT1988779E (pt) 2006-02-16 2015-09-04 Anacor Pharmaceuticals Inc Moléculas pequenas contendo boro como agentes antiinflamatórios
US20070286822A1 (en) * 2006-06-12 2007-12-13 Anacor Pharmaceuticals Inc. Compounds for the Treatment of Periodontal Disease
JO3396B1 (ar) 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
WO2010045505A1 (en) 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc Boron-containing small molecules as anti-protozoal agents
WO2010045503A1 (en) 2008-10-15 2010-04-22 Anacor Pharmaceuticals, Inc. Boron-containing small molecules as anti-protozoal agents

Also Published As

Publication number Publication date
US8106031B2 (en) 2012-01-31
BRPI0711155A2 (pt) 2011-08-23
EP2015757A2 (en) 2009-01-21
US20070265226A1 (en) 2007-11-15
EP2015757A4 (en) 2011-01-26
WO2007131072A3 (en) 2008-07-03
WO2007131072A2 (en) 2007-11-15
JP2009536660A (ja) 2009-10-15

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Legal Events

Date Code Title Description
FZDE Discontinued