CA2647796A1 - Method of inhibiting osteoclast activity - Google Patents
Method of inhibiting osteoclast activity Download PDFInfo
- Publication number
- CA2647796A1 CA2647796A1 CA002647796A CA2647796A CA2647796A1 CA 2647796 A1 CA2647796 A1 CA 2647796A1 CA 002647796 A CA002647796 A CA 002647796A CA 2647796 A CA2647796 A CA 2647796A CA 2647796 A1 CA2647796 A1 CA 2647796A1
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physical Education & Sports Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Marine Sciences & Fisheries (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14609499P | 1999-07-28 | 1999-07-28 | |
| US60/146,094 | 1999-07-28 | ||
| CA002380007A CA2380007A1 (en) | 1999-07-28 | 2000-07-28 | Methods of inhibiting osteoclast activity |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002380007A Division CA2380007A1 (en) | 1999-07-28 | 2000-07-28 | Methods of inhibiting osteoclast activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2647796A1 true CA2647796A1 (en) | 2001-02-08 |
Family
ID=22515834
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002647796A Abandoned CA2647796A1 (en) | 1999-07-28 | 2000-07-28 | Method of inhibiting osteoclast activity |
| CA002380007A Abandoned CA2380007A1 (en) | 1999-07-28 | 2000-07-28 | Methods of inhibiting osteoclast activity |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002380007A Abandoned CA2380007A1 (en) | 1999-07-28 | 2000-07-28 | Methods of inhibiting osteoclast activity |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1207873B1 (https=) |
| JP (1) | JP4790179B2 (https=) |
| AT (1) | ATE448781T1 (https=) |
| AU (2) | AU778190B2 (https=) |
| CA (2) | CA2647796A1 (https=) |
| DE (1) | DE60043346D1 (https=) |
| WO (1) | WO2001008677A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU777634B2 (en) * | 1999-07-28 | 2004-10-28 | Kazuhiro Aoki | Methods of inhibiting osteoclastogenesis |
| ATE366306T1 (de) | 2000-09-22 | 2007-07-15 | Immunex Corp | Screeningverfahren für agonisten und antagonisten des rezeptoraktivators von nf-kappa b |
| DE50212445D1 (de) | 2001-07-03 | 2008-08-14 | Febit Holding Gmbh | Zweistufige schutzgruppen für die synthese von biopolymeren |
| ES2465216T3 (es) * | 2007-06-04 | 2014-06-05 | Ben Gurion University Of The Negev Research And Development Authority | Compuestos de triarilo y composiciones que comprenden los mismos |
| JP5191487B2 (ja) * | 2007-06-05 | 2013-05-08 | オリエンタル酵母工業株式会社 | 新しい骨量増加薬 |
| WO2009144738A1 (en) * | 2008-05-13 | 2009-12-03 | Ashok Ranganath Shelar | Medicinal applications of benzoic acid hydrazones synthesized on the basis of steroidal tigogenin |
| WO2013035852A1 (ja) | 2011-09-09 | 2013-03-14 | 住友電気工業株式会社 | 給電システム及び接続コネクタ |
| WO2014062625A1 (en) * | 2012-10-15 | 2014-04-24 | Iowa State University Research Foundation, Inc. | Tackifier compounds and methods of using the same |
| RU2015141934A (ru) * | 2013-03-15 | 2017-04-20 | Фарматрофикс, Инк. | Непептидные миметики нейротрофина bdnf |
| JP2016519668A (ja) | 2013-03-15 | 2016-07-07 | ファーマトロフィックス， インコーポレイテッド | 非ペプチドｂｄｎｆニューロトロフィン模倣化合物 |
| US9321803B2 (en) * | 2013-07-12 | 2016-04-26 | Children's Hospital Medical Center | Compositions and methods for inhibiting norovirus infection |
| CR20160207A (es) | 2013-11-05 | 2016-08-10 | Ben Gurion Univ Of The Negev Res And Dev Authority | Compuestos para el tratamiento de la diabetes y las complicaciones que surgen de la misma enfermedad |
| US10077257B2 (en) | 2015-04-06 | 2018-09-18 | Iowa State University Research Foundation, Inc. | Aziridinated triglycerides and polymers formed therefrom |
| US10392471B2 (en) | 2015-05-14 | 2019-08-27 | Iowa State University Research Foundation, Inc. | Polymers and methods of making the same |
| AU2016265523B2 (en) * | 2015-05-20 | 2019-07-18 | Osaka University | Oligopeptide having proinflammatory cytokine secretion-inhibiting activity |
| EP3600397A4 (en) | 2017-03-28 | 2021-01-27 | Children's Hospital Medical Center | NOROVIRUS PARTICLE VACCINES AND THEIR MANUFACTURING AND USE PROCEDURES |
| CN110229118B (zh) * | 2019-06-28 | 2021-03-02 | 深圳市三启药物开发有限公司 | 腙酰胺类衍生物及其在制备抗骨质疏松药物中的应用 |
| CN111686116B (zh) * | 2020-06-08 | 2021-05-04 | 广东省微生物研究所（广东省微生物分析检测中心） | 孕甾烷衍生物在制备破骨细胞分化抑制剂中的应用 |
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| US6242213B1 (en) * | 1996-12-23 | 2001-06-05 | Immunex Corporation | Isolated DNA molecules encoding RANK-L |
| WO1999058674A2 (en) * | 1998-05-14 | 1999-11-18 | Immunex Corporation | Method of inhibiting osteoclast activity |
| WO2000001349A2 (en) * | 1998-07-01 | 2000-01-13 | The Trustees Of The University Of Pennsylvania | Cavity induced allosteric modification of intermolecular interactions and methods of identifying compounds that effect the same |
| CN1318105A (zh) * | 1998-09-15 | 2001-10-17 | M&E生物技术公司 | 负调节Osteoprotegerin配体活性的方法 |
| AU777634B2 (en) * | 1999-07-28 | 2004-10-28 | Kazuhiro Aoki | Methods of inhibiting osteoclastogenesis |
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| JP4790179B2 (ja) | 2011-10-12 |
| EP1207873A1 (en) | 2002-05-29 |
| ATE448781T1 (de) | 2009-12-15 |
| EP1207873B1 (en) | 2009-11-18 |
| AU2005200650B2 (en) | 2007-11-15 |
| AU2005200650A1 (en) | 2005-03-10 |
| AU6384600A (en) | 2001-02-19 |
| WO2001008677A8 (en) | 2001-07-12 |
| DE60043346D1 (de) | 2009-12-31 |
| JP2003505503A (ja) | 2003-02-12 |
| CA2380007A1 (en) | 2001-02-08 |
| WO2001008677A1 (en) | 2001-02-08 |
| AU778190B2 (en) | 2004-11-18 |
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