ATE448781T1 - Methoden zur hemmung der aktivität der osteoklasten - Google Patents
Methoden zur hemmung der aktivität der osteoklastenInfo
- Publication number
- ATE448781T1 ATE448781T1 AT00950797T AT00950797T ATE448781T1 AT E448781 T1 ATE448781 T1 AT E448781T1 AT 00950797 T AT00950797 T AT 00950797T AT 00950797 T AT00950797 T AT 00950797T AT E448781 T1 ATE448781 T1 AT E448781T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- trance
- disclosed
- osteoclasts
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
- A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/1013—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1021—Tetrapeptides with the first amino acid being acidic
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14609499P | 1999-07-28 | 1999-07-28 | |
PCT/US2000/020502 WO2001008677A1 (en) | 1999-07-28 | 2000-07-28 | Methods of inhibiting osteoclast activity |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE448781T1 true ATE448781T1 (de) | 2009-12-15 |
Family
ID=22515834
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00950797T ATE448781T1 (de) | 1999-07-28 | 2000-07-28 | Methoden zur hemmung der aktivität der osteoklasten |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1207873B1 (de) |
JP (1) | JP4790179B2 (de) |
AT (1) | ATE448781T1 (de) |
AU (2) | AU778190B2 (de) |
CA (2) | CA2380007A1 (de) |
DE (1) | DE60043346D1 (de) |
WO (1) | WO2001008677A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2380009A1 (en) * | 1999-07-28 | 2001-02-08 | The Trustees Of The University Of Pennsylvania | Methods of inhibiting osteoclastogenesis |
US6884598B2 (en) | 2000-09-22 | 2005-04-26 | Immunex Corporation | Screening assays for agonists and antagonists of receptor activator of NF-κB |
WO2003004510A1 (de) | 2001-07-03 | 2003-01-16 | Febit Ag | Zweistufige schutzgruppen für die synthese von biopolymeren |
MX2009013354A (es) | 2007-06-04 | 2010-07-06 | Univ Ben Gurion | Compuestos de triarilo y composiciones que los contienen. |
CA2689518A1 (en) | 2007-06-05 | 2008-12-11 | Oriental Yeast Co., Ltd. | A novel bone mass increasing agent |
EP2279195B1 (de) * | 2008-05-13 | 2013-05-15 | Ashok Ranganath Shelar | Medizinische anwendungen von auf basis von steroidem tigogenin synthetisierten benzoesäurehydrazonen |
JP5876495B2 (ja) | 2011-09-09 | 2016-03-02 | 住友電気工業株式会社 | 給電システム及び接続コネクタ |
US9688794B2 (en) | 2012-10-15 | 2017-06-27 | Iowa State University Research Foundation, Inc. | Tackifier compounds and methods of using the same |
US9828332B2 (en) | 2013-03-15 | 2017-11-28 | PharmatorophiX, Inc. | Non-peptide BDNF neurotrophin mimetics |
US9828330B2 (en) | 2013-03-15 | 2017-11-28 | Pharmatrophix, Inc. | Non-peptide BDNF neurotrophin mimetics |
US9321803B2 (en) * | 2013-07-12 | 2016-04-26 | Children's Hospital Medical Center | Compositions and methods for inhibiting norovirus infection |
WO2015068156A1 (en) | 2013-11-05 | 2015-05-14 | Ben-Gurion University Of The Negev Research And Development Authority | Compounds for the treatment of diabetes and disease complications arising from same |
US10077257B2 (en) | 2015-04-06 | 2018-09-18 | Iowa State University Research Foundation, Inc. | Aziridinated triglycerides and polymers formed therefrom |
US10392471B2 (en) | 2015-05-14 | 2019-08-27 | Iowa State University Research Foundation, Inc. | Polymers and methods of making the same |
CN108064231A (zh) | 2015-05-20 | 2018-05-22 | 国立大学法人大阪大学 | 具有炎性细胞因子分泌抑制活性的寡肽 |
US11833198B2 (en) | 2017-03-28 | 2023-12-05 | Children's Hospital Medical Center | Norovirus S particle based vaccines and methods of making and using same |
CN111686116B (zh) * | 2020-06-08 | 2021-05-04 | 广东省微生物研究所(广东省微生物分析检测中心) | 孕甾烷衍生物在制备破骨细胞分化抑制剂中的应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2274987C (en) * | 1996-12-23 | 2012-01-24 | Immunex Corporation | Ligand for receptor activator of nf-kappa b, ligand is member of tnf superfamily |
EP2009025B1 (de) * | 1998-05-14 | 2011-07-27 | Immunex Corporation | Verfahren zur Hemmung der Wirkung der Osteoklasten |
AU762749B2 (en) * | 1998-07-01 | 2003-07-03 | Trustees Of The University Of Pennsylvania, The | Cavity induced allosteric modification of intermolecular interactions and methods of identifying compounds that effect the same |
PL196790B1 (pl) * | 1998-09-15 | 2008-01-31 | Pharmexa As | Zastosowanie zwierzęcego polipeptydu OPGL lub jego podsekwencji, lub analogu OPGL, zastosowanie fragmentu kwasu nukleinowego, zastosowanie wektora przenoszącego fragment kwasu nukleinowego, zastosowanie niepatogennej transformowanej komórki, zastosowanie kompozycji zawierającej taki fragment lub wektor, sposób identyfikacji zmodyfikowanego polipeptydu OPGL, sposób wytwarzania kompozycji immunogennej |
CA2380009A1 (en) * | 1999-07-28 | 2001-02-08 | The Trustees Of The University Of Pennsylvania | Methods of inhibiting osteoclastogenesis |
-
2000
- 2000-07-28 AT AT00950797T patent/ATE448781T1/de not_active IP Right Cessation
- 2000-07-28 AU AU63846/00A patent/AU778190B2/en not_active Ceased
- 2000-07-28 DE DE60043346T patent/DE60043346D1/de not_active Expired - Lifetime
- 2000-07-28 CA CA002380007A patent/CA2380007A1/en not_active Abandoned
- 2000-07-28 JP JP2001513407A patent/JP4790179B2/ja not_active Expired - Fee Related
- 2000-07-28 CA CA002647796A patent/CA2647796A1/en not_active Abandoned
- 2000-07-28 EP EP00950797A patent/EP1207873B1/de not_active Expired - Lifetime
- 2000-07-28 WO PCT/US2000/020502 patent/WO2001008677A1/en active IP Right Grant
-
2005
- 2005-02-14 AU AU2005200650A patent/AU2005200650B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
WO2001008677A1 (en) | 2001-02-08 |
WO2001008677A8 (en) | 2001-07-12 |
DE60043346D1 (de) | 2009-12-31 |
AU6384600A (en) | 2001-02-19 |
AU778190B2 (en) | 2004-11-18 |
EP1207873B1 (de) | 2009-11-18 |
JP4790179B2 (ja) | 2011-10-12 |
AU2005200650B2 (en) | 2007-11-15 |
CA2380007A1 (en) | 2001-02-08 |
AU2005200650A1 (en) | 2005-03-10 |
CA2647796A1 (en) | 2001-02-08 |
EP1207873A4 (de) | 2006-04-12 |
EP1207873A1 (de) | 2002-05-29 |
JP2003505503A (ja) | 2003-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |