CA2645302C - Diagnosis and prognosis of dipeptidyl peptidase-associated disease states - Google Patents

Diagnosis and prognosis of dipeptidyl peptidase-associated disease states Download PDF

Info

Publication number
CA2645302C
CA2645302C CA2645302A CA2645302A CA2645302C CA 2645302 C CA2645302 C CA 2645302C CA 2645302 A CA2645302 A CA 2645302A CA 2645302 A CA2645302 A CA 2645302A CA 2645302 C CA2645302 C CA 2645302C
Authority
CA
Canada
Prior art keywords
dpp
activity
measured
isoforms
portions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2645302A
Other languages
English (en)
French (fr)
Other versions
CA2645302A1 (en
Inventor
Patrick O'mullan
Craig A. Gelfand
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of CA2645302A1 publication Critical patent/CA2645302A1/en
Application granted granted Critical
Publication of CA2645302C publication Critical patent/CA2645302C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/04Endocrine or metabolic disorders
    • G01N2800/042Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
CA2645302A 2006-03-13 2007-03-13 Diagnosis and prognosis of dipeptidyl peptidase-associated disease states Active CA2645302C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US78192406P 2006-03-13 2006-03-13
US60/781,924 2006-03-13
US80439706P 2006-06-09 2006-06-09
US60/804,397 2006-06-09
US89276707P 2007-03-02 2007-03-02
US60/892,767 2007-03-02
PCT/US2007/006653 WO2007106595A1 (en) 2006-03-13 2007-03-13 Diagnosis and prognosis of dipeptidyl peptidase-associated disease states

Publications (2)

Publication Number Publication Date
CA2645302A1 CA2645302A1 (en) 2007-09-20
CA2645302C true CA2645302C (en) 2017-07-11

Family

ID=38265130

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2645302A Active CA2645302C (en) 2006-03-13 2007-03-13 Diagnosis and prognosis of dipeptidyl peptidase-associated disease states

Country Status (11)

Country Link
US (1) US8652789B2 (https=)
EP (1) EP1994415B9 (https=)
JP (1) JP5410955B2 (https=)
KR (1) KR101376471B1 (https=)
CN (1) CN101460851B (https=)
AU (1) AU2007225054B2 (https=)
BR (1) BRPI0708900A2 (https=)
CA (1) CA2645302C (https=)
ES (1) ES2549860T3 (https=)
MX (1) MX2008011665A (https=)
WO (1) WO2007106595A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2527649T3 (es) * 2007-12-10 2015-01-28 F. Hoffmann-La Roche Ag Panel de marcadores para el cáncer colorrectal
ES2533428T3 (es) * 2009-05-04 2015-04-10 F. Hoffmann-La Roche Ag Uso de DPPIV/Seprasa como un marcador para el cáncer
JP6065172B2 (ja) * 2010-10-22 2017-01-25 国立大学法人名古屋大学 微小血管障害又はその関連疾患のバイオマーカー
US20140273008A1 (en) * 2013-03-15 2014-09-18 Molecular Bioproducts, Inc. Methods to assess enzyme activity using mass spectrometric immunoassay
EP3314004A1 (en) * 2015-06-26 2018-05-02 DuPont Nutrition Biosciences ApS Aminopeptidases for protein hydrolyzates
AU2017252212B2 (en) * 2016-04-21 2023-09-07 4TEEN4 Pharmaceuticals GmbH Methods for determining DPP3 and therapeutic methods
CN110426518A (zh) * 2019-07-19 2019-11-08 宁波熙宁检测技术有限公司 一种定量检测人类血浆中dpp-4酶活性的方法
EP4308937B1 (en) * 2021-03-16 2026-02-04 Astrazeneca AB System and method for online detection of a post-translational modification of a polypeptide

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900662A (en) 1987-07-21 1990-02-13 International Immunoassay Laboratories, Inc. CK-MM myocardial infarction immunoassay
US5382515A (en) 1987-07-21 1995-01-17 International Immunoassay Laboratories, Inc. Creative kinase-MB immunoassay for myocardial infarction and reagents
US5382522A (en) 1987-07-21 1995-01-17 International Immunoassay Laboratories, Inc. Immunoassay for creatine kinase-MB and creatine kinase-BB isoforms and reagents
EP1631680A2 (en) * 2003-05-21 2006-03-08 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with dipeptidylpeptidase iv (dpp4)
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors

Also Published As

Publication number Publication date
JP2009529884A (ja) 2009-08-27
AU2007225054A1 (en) 2007-09-20
CA2645302A1 (en) 2007-09-20
US8652789B2 (en) 2014-02-18
EP1994415B9 (en) 2015-12-16
ES2549860T3 (es) 2015-11-02
KR101376471B1 (ko) 2014-03-27
JP5410955B2 (ja) 2014-02-05
CN101460851B (zh) 2016-09-21
EP1994415B1 (en) 2015-07-29
WO2007106595A1 (en) 2007-09-20
AU2007225054B2 (en) 2012-08-16
MX2008011665A (es) 2008-10-08
KR20090008218A (ko) 2009-01-21
EP1994415A1 (en) 2008-11-26
US20070264671A1 (en) 2007-11-15
CN101460851A (zh) 2009-06-17
BRPI0708900A2 (pt) 2011-06-14

Similar Documents

Publication Publication Date Title
CA2645302C (en) Diagnosis and prognosis of dipeptidyl peptidase-associated disease states
Lahiri et al. Systemic inflammatory response syndrome after major abdominal surgery predicted by early upregulation of TLR4 and TLR5
Ghallab et al. Serum and salivary levels of chemerin and MMP-9 in oral squamous cell carcinoma and oral premalignant lesions
Morgan et al. Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping
Esteghamat et al. CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation
US20190264283A1 (en) URINE EXOSOME mRNAS AND METHODS OF USING SAME TO DETECT DIABETIC NEPHROPATHY
JP2002131322A5 (https=)
AU2020388534A1 (en) Device and method for detecting of brain injury in a subject
Koh et al. Single cell transcriptomes derived from human cervical and uterine tissue during pregnancy
Jimbo et al. Placenta increta: postpartum monitoring of plasma cell-free fetal DNA
Soluble Insulin Receptor Study Group Soluble insulin receptor ectodomain is elevated in the plasma of patients with diabetes
Kumar et al. Estimation of YKL-40 levels in serum and gingival crevicular fluid in chronic periodontitis and type 2 diabetes patients among south Indian population: A clinical study
Saadi et al. Predictors of successful outcome after adrenalectomy for unilateral primary aldosteronism
Balistreri et al. The role of inflammation in type A aortic dissection: a pilot study
RU2000119129A (ru) Молекула днк, кодирующая мутантный препронейропептид y, мутантный сигнальный пептид и их применения
AL-khaykanee et al. A review about liver function tests
Evangelopoulos et al. The impact of demographic characteristics and lifestyle in the distribution of cystatin C values in a healthy Greek adult population
Abdulraheem et al. Diagnostic value of Interleukin-40 and Interleukin-41 for Diabetic Kidney Disease and Diabetes
Van Langendonckt et al. Identification of novel antigens in blood vessels in rectovaginal endometriosis
Hyodo et al. Molar DNA in maternal serum in a case of 46, XY heterozygous complete hydatidiform mole coexisting with a 46, XX twin live fetus
Jankowski et al. Biomarkers identifying deterioration of kidney graft function—usefulness of “liquid biopsy”
US7759086B2 (en) Diagnostic method for chronic fatigue syndrome by measuring elastase
Shenoy et al. Lipid-bound sialic acid in psoriasis and its correlation with disease severity
Chauhan et al. Spot Urine Protein to Creatinine Ratio in Patients with Urinary Tract Infection
Kalpidis Role of Salivary Biomarkers in Diagnosis and Monitoring of Patients with Autoimmune Diseases: A Systematic Review

Legal Events

Date Code Title Description
EEER Examination request
MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 18TH ANNIV.) - STANDARD

Year of fee payment: 18

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250224

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20251006

MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 19TH ANNIV.) - STANDARD

Year of fee payment: 19

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20260226

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL

Effective date: 20260226