CA2634692A1 - Diagnostic methods involving determining gene copy numbers and snps in the fc.gamma.rii/fc.gamma.riii gene cluster, and probes for use in such methods to detect susceptibility to and treatment efficacy in autoimmune diseases - Google Patents
Diagnostic methods involving determining gene copy numbers and snps in the fc.gamma.rii/fc.gamma.riii gene cluster, and probes for use in such methods to detect susceptibility to and treatment efficacy in autoimmune diseases Download PDFInfo
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- CA2634692A1 CA2634692A1 CA002634692A CA2634692A CA2634692A1 CA 2634692 A1 CA2634692 A1 CA 2634692A1 CA 002634692 A CA002634692 A CA 002634692A CA 2634692 A CA2634692 A CA 2634692A CA 2634692 A1 CA2634692 A1 CA 2634692A1
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Peptides Or Proteins (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05077984.2 | 2005-12-22 | ||
| EP05077984A EP1801234A1 (de) | 2005-12-22 | 2005-12-22 | Diagnostische Verfahren, welche die Anzahl von Genkopien und deren Verwendung miteinbeziehen |
| PCT/NL2006/000662 WO2007073179A2 (en) | 2005-12-22 | 2006-12-22 | DIAGNOSTIC METHODS INVOLVING DETERMINING GENE COPY NUMBERS AND SNPs IN THE FcϜRII/FcϜRIII GENE CLUSTER, AND PROBES FOR USE IN SUCH METHODS TO DETECT SUSCEPTIBILITY TO AND TREATMENT EFFICACY IN AUTOIMMUNE DISEASES |
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| Country | Link |
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| US (2) | US7994300B2 (de) |
| EP (2) | EP1801234A1 (de) |
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| PT (1) | PT1989323E (de) |
| WO (1) | WO2007073179A2 (de) |
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| US9157118B2 (en) | 2007-10-09 | 2015-10-13 | Arkray, Inc. | Probes for detecting immune-related gene polymorphisms and applications of the same |
| EP2055790A1 (de) * | 2007-10-30 | 2009-05-06 | Leibniz-Institut für Altersforschung - Fritz-Lipmann-Institut e.V. | Kalibriermolekül und Verfahren zur Bestimmung der Anzahl Kopien von Gen-/Zielloci in einem Genom unter Verwendung dieses Kalibriermoleküls |
| US20120030144A1 (en) * | 2007-11-08 | 2012-02-02 | Pikamab, Inc. | Methods for doing business using biomarkers |
| US20100330568A1 (en) * | 2008-01-09 | 2010-12-30 | Stefan Meuer | Assay and method for the assessment of responders and non-responders to nk cell modulation by immunoglobulin therapy |
| US20110268753A1 (en) * | 2009-01-08 | 2011-11-03 | The Uab Research Foundation | Process for regulating immune response |
| CN102959088A (zh) * | 2010-02-02 | 2013-03-06 | 艾博特生物技术有限公司 | 用于预测对TNF-α抑制剂治疗的反应性的方法和组合物 |
| US20140336950A1 (en) * | 2011-11-16 | 2014-11-13 | Univerisity of South Dakota | Clustering copy-number values for segments of genomic data |
| CN118222709A (zh) * | 2024-03-25 | 2024-06-21 | 南京医科大学 | FcγRIIA作为胶质瘤生物标志物和治疗靶点的应用 |
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| US5830652A (en) * | 1994-08-30 | 1998-11-03 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method for determining predisposition to severe forms of autoimmune disease by determining Fcy receptor allelic patterns |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| EP1511690A4 (de) * | 2002-05-16 | 2007-10-24 | Univ Vanderbilt | Verfahren zur vorhersage von autoimmunerkrankungen |
| US7425620B2 (en) * | 2002-08-14 | 2008-09-16 | Scott Koenig | FcγRIIB-specific antibodies and methods of use thereof |
| US20080248465A1 (en) | 2004-04-26 | 2008-10-09 | Uab Research Foundation | Polymorphisms in the Fcgr2b Promoter and Uses Thereof |
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Also Published As
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| EP1989323A2 (de) | 2008-11-12 |
| ES2369415T3 (es) | 2011-11-30 |
| AU2006327982A8 (en) | 2008-07-24 |
| US20110189672A1 (en) | 2011-08-04 |
| ATE515580T1 (de) | 2011-07-15 |
| WO2007073179A3 (en) | 2008-01-17 |
| PT1989323E (pt) | 2011-09-29 |
| PL1989323T3 (pl) | 2011-12-30 |
| US7994300B2 (en) | 2011-08-09 |
| EP1989323B1 (de) | 2011-07-06 |
| EP1801234A1 (de) | 2007-06-27 |
| AU2006327982A1 (en) | 2007-06-28 |
| US8765372B2 (en) | 2014-07-01 |
| DK1989323T3 (da) | 2011-09-26 |
| US20090263795A1 (en) | 2009-10-22 |
| WO2007073179A2 (en) | 2007-06-28 |
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