CA2629522A1 - Gene therapy for renal failure - Google Patents
Gene therapy for renal failure Download PDFInfo
- Publication number
- CA2629522A1 CA2629522A1 CA002629522A CA2629522A CA2629522A1 CA 2629522 A1 CA2629522 A1 CA 2629522A1 CA 002629522 A CA002629522 A CA 002629522A CA 2629522 A CA2629522 A CA 2629522A CA 2629522 A1 CA2629522 A1 CA 2629522A1
- Authority
- CA
- Canada
- Prior art keywords
- bmp
- seq
- polypeptide
- group
- signal peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73645205P | 2005-11-14 | 2005-11-14 | |
| US60/736,452 | 2005-11-14 | ||
| PCT/US2006/044048 WO2007056614A1 (en) | 2005-11-14 | 2006-11-14 | Gene therapy for renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2629522A1 true CA2629522A1 (en) | 2007-05-18 |
Family
ID=37734130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002629522A Abandoned CA2629522A1 (en) | 2005-11-14 | 2006-11-14 | Gene therapy for renal failure |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7598364B2 (enExample) |
| EP (4) | EP2186823A1 (enExample) |
| JP (1) | JP2009515529A (enExample) |
| CA (1) | CA2629522A1 (enExample) |
| WO (1) | WO2007056614A1 (enExample) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7771995B2 (en) * | 2005-11-14 | 2010-08-10 | Merial Limited | Plasmid encoding human BMP-7 |
| US20100291173A1 (en) * | 2006-09-05 | 2010-11-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of improving renal function |
| EP2086580A2 (en) * | 2006-11-21 | 2009-08-12 | Merial Limited | Prime boost canine leishmania vaccine |
| US20120322861A1 (en) * | 2007-02-23 | 2012-12-20 | Barry John Byrne | Compositions and Methods for Treating Diseases |
| US7846428B2 (en) | 2007-10-05 | 2010-12-07 | Merial Limited | Articular cartilage gene therapy with recombinant vector encoding BMP-7 |
| SMT202000445T1 (it) | 2012-06-19 | 2020-09-10 | Univ Florida | Composizioni e metodi per trattare patologie |
| ES2752190T3 (es) | 2012-09-14 | 2020-04-03 | Us Health | Proteína Brachyury, vectores adenovirales que codifican proteína Brachyury y su uso |
| EP2951290B1 (en) | 2013-02-01 | 2017-11-29 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
| EP4137150A1 (en) | 2015-08-03 | 2023-02-22 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use |
| KR102781602B1 (ko) | 2015-09-08 | 2025-03-18 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 임상 등급 망막 색소 상피 세포의 재현성 있는 분화 방법 |
| CA2997763A1 (en) | 2015-09-08 | 2017-03-16 | Cellular Dynamics International, Inc. | Macs-based purification of stem cell-derived retinal pigment epithelium |
| JP7099967B2 (ja) | 2016-07-01 | 2022-07-12 | リサーチ ディベロップメント ファウンデーション | 幹細胞由来移植片からの増殖性細胞の排除 |
| US11866733B2 (en) | 2016-08-01 | 2024-01-09 | University of Pittsburgh—of the Commonwealth System of Higher Education | Human induced pluripotent stem cells for high efficiency genetic engineering |
| EP3523422B1 (en) | 2016-10-05 | 2024-12-25 | FUJIFILM Cellular Dynamics, Inc. | Generating mature lineages from induced pluripotent stem cells with mecp2 disruption |
| AU2017359330B2 (en) | 2016-11-09 | 2022-03-10 | The United States Of America, As Represented By The Secretary Department Of Health And Human Services | 3D vascularized human ocular tissue for cell therapy and drug discovery |
| EP3583201B1 (en) | 2017-02-14 | 2024-01-17 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Methods of engineering human induced pluripotent stem cells to produce liver tissue |
| AU2018254442B2 (en) | 2017-04-18 | 2024-03-28 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| AU2019256723B2 (en) | 2018-04-20 | 2025-09-04 | FUJIFILM Cellular Dynamics, Inc. | Method for differentiation of ocular cells and use thereof |
| WO2020086408A1 (en) | 2018-10-26 | 2020-04-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A high-yield perfusion-based transient gene expression bioprocess |
| IL282791B2 (en) | 2018-11-19 | 2026-03-01 | Us Health | Biodegradable tissue replacement implant and its use |
| AU2019386140A1 (en) | 2018-11-28 | 2021-06-24 | Board Of Regents, The University Of Texas System | Multiplex genome editing of immune cells to enhance functionality and resistance to suppressive environment |
| WO2020112493A1 (en) | 2018-11-29 | 2020-06-04 | Board Of Regents, The University Of Texas System | Methods for ex vivo expansion of natural killer cells and use thereof |
| PH12022552993A1 (en) | 2020-05-29 | 2023-01-16 | Fujifilm Cellular Dynamics Inc | Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof |
| BR112022024064A2 (pt) | 2020-05-29 | 2023-01-31 | Fujifilm Cellular Dynamics Inc | Bicamada de epitélio pigmentado da retina e fotorreceptores e uso dos mesmos |
| WO2022251443A1 (en) | 2021-05-26 | 2022-12-01 | FUJIFILM Cellular Dynamics, Inc. | Methods to prevent rapid silencing of genes in pluripotent stem cells |
| ES3064924T3 (en) | 2021-05-28 | 2026-04-30 | Us Health | Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells |
| JP2024520424A (ja) | 2021-05-28 | 2024-05-24 | ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 黄斑、中心および末梢網膜色素上皮細胞を生成する方法 |
| EP4402249A1 (en) | 2021-09-13 | 2024-07-24 | Fujifilm Cellular Dynamics, Inc. | Methods for the production of committed cardiac progenitor cells |
| WO2024006911A1 (en) | 2022-06-29 | 2024-01-04 | FUJIFILM Holdings America Corporation | Ipsc-derived astrocytes and methods of use thereof |
| US20240139256A1 (en) | 2022-09-30 | 2024-05-02 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of cardiac fibroblasts |
| WO2024192329A1 (en) | 2023-03-16 | 2024-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for producing stable human chondroctyes and their use for promoting cartillage growth and repair |
| WO2025245202A1 (en) | 2024-05-21 | 2025-11-27 | FUJIFILM Cellular Dynamics, Inc. | Particle counting and biomass measurements of aggregated cell compositions |
| US20260021201A1 (en) * | 2024-07-18 | 2026-01-22 | Wyvern Pharmaceuticals Inc. | Composition for regulating production of proteins |
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| US20100291173A1 (en) | 2006-09-05 | 2010-11-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of improving renal function |
-
2006
- 2006-11-14 CA CA002629522A patent/CA2629522A1/en not_active Abandoned
- 2006-11-14 EP EP10150052A patent/EP2186823A1/en not_active Ceased
- 2006-11-14 US US11/599,026 patent/US7598364B2/en active Active
- 2006-11-14 EP EP19167572.7A patent/EP3536704B1/en active Active
- 2006-11-14 EP EP16178703.1A patent/EP3147296A1/en not_active Ceased
- 2006-11-14 WO PCT/US2006/044048 patent/WO2007056614A1/en not_active Ceased
- 2006-11-14 JP JP2008540260A patent/JP2009515529A/ja active Pending
- 2006-11-14 EP EP06827775.5A patent/EP1951751B1/en active Active
-
2008
- 2008-11-19 US US12/273,931 patent/US7772205B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3147296A1 (en) | 2017-03-29 |
| EP3536704A1 (en) | 2019-09-11 |
| EP1951751A1 (en) | 2008-08-06 |
| US7598364B2 (en) | 2009-10-06 |
| US20090082301A1 (en) | 2009-03-26 |
| US7772205B2 (en) | 2010-08-10 |
| US20070155688A1 (en) | 2007-07-05 |
| EP2186823A1 (en) | 2010-05-19 |
| JP2009515529A (ja) | 2009-04-16 |
| EP3536704B1 (en) | 2021-08-25 |
| WO2007056614A1 (en) | 2007-05-18 |
| EP1951751B1 (en) | 2017-11-01 |
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