CA2628926C - Mass spectrometer - Google Patents

Mass spectrometer Download PDF

Info

Publication number
CA2628926C
CA2628926C CA2628926A CA2628926A CA2628926C CA 2628926 C CA2628926 C CA 2628926C CA 2628926 A CA2628926 A CA 2628926A CA 2628926 A CA2628926 A CA 2628926A CA 2628926 C CA2628926 C CA 2628926C
Authority
CA
Canada
Prior art keywords
ions
ion
mass
parent
fragmentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2628926A
Other languages
English (en)
French (fr)
Other versions
CA2628926A1 (en
Inventor
Robert Harold Bateman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Micromass UK Ltd
Original Assignee
Micromass UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Micromass UK Ltd filed Critical Micromass UK Ltd
Publication of CA2628926A1 publication Critical patent/CA2628926A1/en
Application granted granted Critical
Publication of CA2628926C publication Critical patent/CA2628926C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Nanotechnology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CA2628926A 2005-11-23 2006-11-23 Mass spectrometer Active CA2628926C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US73926905P 2005-11-23 2005-11-23
GB0523812.6 2005-11-23
GB0523812A GB2432712B (en) 2005-11-23 2005-11-23 Mass spectrometer
US60/739269 2005-11-23
PCT/GB2006/004370 WO2007060427A2 (en) 2005-11-23 2006-11-23 Mass spectrometer

Publications (2)

Publication Number Publication Date
CA2628926A1 CA2628926A1 (en) 2007-05-31
CA2628926C true CA2628926C (en) 2013-01-08

Family

ID=35601032

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2628926A Active CA2628926C (en) 2005-11-23 2006-11-23 Mass spectrometer

Country Status (6)

Country Link
US (1) US7928363B2 (enExample)
EP (1) EP1952423A2 (enExample)
JP (1) JP4778564B2 (enExample)
CA (1) CA2628926C (enExample)
GB (1) GB2432712B (enExample)
WO (1) WO2007060427A2 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115056A1 (en) * 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
GB0305796D0 (en) * 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
GB0609253D0 (en) * 2006-05-10 2006-06-21 Micromass Ltd Mass spectrometer
JP4996962B2 (ja) * 2007-04-04 2012-08-08 株式会社日立ハイテクノロジーズ 質量分析装置
KR100989817B1 (ko) * 2007-07-24 2010-10-29 다우어드밴스드디스플레이머티리얼 유한회사 신규한 적색 인광 화합물 및 이를 발광재료로서 채용하고있는 유기 전계 발광 소자
CA2718535C (en) * 2008-03-20 2017-06-06 Dh Technologies Development Pte. Ltd. Systems and methods for analyzing substances using a mass spectrometer
DE102009035587B3 (de) * 2009-07-31 2011-03-24 Siemens Aktiengesellschaft Verfahren zur Filterung eines Chromatogramms
GB0915474D0 (en) * 2009-09-04 2009-10-07 Micromass Ltd Multiple reaction monitoring with a time-of-flight based mass spectrometer
EP2617052B1 (en) * 2010-09-15 2022-06-08 DH Technologies Development Pte. Ltd. Data independent acquisition of production spectra and reference spectra library matching
US8935101B2 (en) 2010-12-16 2015-01-13 Thermo Finnigan Llc Method and apparatus for correlating precursor and product ions in all-ions fragmentation experiments
GB201111560D0 (en) * 2011-07-06 2011-08-24 Micromass Ltd Photo-dissociation of proteins and peptides in a mass spectrometer
GB201122178D0 (en) 2011-12-22 2012-02-01 Thermo Fisher Scient Bremen Method of tandem mass spectrometry
GB2503538B (en) * 2012-03-27 2015-09-09 Micromass Ltd A method of mass spectrometry and a mass spectrometer
GB201208812D0 (en) * 2012-05-18 2012-07-04 Micromass Ltd Cryogenic collision cell
GB201208961D0 (en) 2012-05-18 2012-07-04 Micromass Ltd 2 dimensional MSMS
EP3598478B1 (en) * 2012-05-18 2025-03-26 Micromass UK Limited Method of ms/ms mass spectrometry
JP6044385B2 (ja) * 2013-02-26 2016-12-14 株式会社島津製作所 タンデム型質量分析装置
CA2912998A1 (en) 2013-05-30 2014-12-04 Dh Technologies Development Pte. Ltd. Inline ion reaction device cell and method of operation
CN105637613B (zh) * 2013-10-16 2018-02-23 Dh科技发展私人贸易有限公司 使用任意传输加窗根据产物离子识别前驱体离子的系统及方法
CN110870043B (zh) * 2017-06-28 2023-07-28 Dh科技发展私人贸易有限公司 用于糖肽分析的设备和方法
CA3074351A1 (en) 2017-09-01 2019-03-07 Perkinelmer Health Sciences Canada, Inc. Systems and methods using a gas mixture to select ions
JP7509762B2 (ja) * 2018-10-09 2024-07-02 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 電子捕獲解離のための電子ビームスロットリング
US20200152437A1 (en) 2018-11-14 2020-05-14 Northrop Grumman Systems Corporation Tapered magnetic ion transport tunnel for particle collection
US11848183B2 (en) * 2019-02-27 2023-12-19 Ohio State Innovation Foundation Ion carpet-based surface-induced dissociation devices and methods
US10755827B1 (en) 2019-05-17 2020-08-25 Northrop Grumman Systems Corporation Radiation shield
CN120190834B (zh) * 2025-05-27 2025-08-12 北华大学 一种机械臂云台动态自适应控制方法

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851669A (en) * 1988-06-02 1989-07-25 The Regents Of The University Of California Surface-induced dissociation for mass spectrometry
US5036014A (en) * 1989-01-31 1991-07-30 Elsohly Mahmoud A Deuterated cannabinoids as standards for the analysis of tetrahydrocannabinol and its metabolites in biological fluids
US5073713A (en) * 1990-05-29 1991-12-17 Battelle Memorial Institute Detection method for dissociation of multiple-charged ions
GB9510052D0 (en) 1995-05-18 1995-07-12 Fisons Plc Mass spectrometer
GB2308917B (en) * 1996-01-05 2000-04-12 Maxent Solutions Ltd Reducing interferences in elemental mass spectrometers
US5885841A (en) * 1996-09-11 1999-03-23 Eli Lilly And Company System and methods for qualitatively and quantitatively comparing complex admixtures using single ion chromatograms derived from spectroscopic analysis of such admixtures
US6323482B1 (en) * 1997-06-02 2001-11-27 Advanced Research And Technology Institute, Inc. Ion mobility and mass spectrometer
GB9717926D0 (en) * 1997-08-22 1997-10-29 Micromass Ltd Methods and apparatus for tandem mass spectrometry
WO1999038194A1 (en) * 1998-01-23 1999-07-29 Analytica Of Branford, Inc. Mass spectrometry from surfaces
CA2303761C (en) * 1999-04-06 2005-12-20 Micromass Limited A method of determining peptide sequences by mass spectrometry
US6487523B2 (en) 1999-04-07 2002-11-26 Battelle Memorial Institute Model for spectral and chromatographic data
US6647341B1 (en) 1999-04-09 2003-11-11 Whitehead Institute For Biomedical Research Methods for classifying samples and ascertaining previously unknown classes
CA2340150C (en) * 2000-06-09 2005-11-22 Micromass Limited Methods and apparatus for mass spectrometry
US6586727B2 (en) * 2000-06-09 2003-07-01 Micromass Limited Methods and apparatus for mass spectrometry
NL1016034C2 (nl) * 2000-08-03 2002-02-08 Tno Werkwijze en systeem voor het identificeren en kwantificeren van chemische componenten van een te onderzoeken mengsel van materialen.
US20020115056A1 (en) * 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
US20020119490A1 (en) * 2000-12-26 2002-08-29 Aebersold Ruedi H. Methods for rapid and quantitative proteome analysis
US6958472B2 (en) * 2001-03-22 2005-10-25 Syddansk Universitet Mass spectrometry methods using electron capture by ions
US6835927B2 (en) * 2001-10-15 2004-12-28 Surromed, Inc. Mass spectrometric quantification of chemical mixture components
GB2396914B (en) 2001-12-08 2005-06-22 Micromass Ltd Method of mass spectrometry
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
WO2003095978A2 (en) 2002-05-09 2003-11-20 Surromed, Inc. Methods for time-alignment of liquid chromatography-mass spectrometry data
US6906319B2 (en) * 2002-05-17 2005-06-14 Micromass Uk Limited Mass spectrometer
CA2487135C (en) 2002-05-31 2009-01-27 Analytica Of Branford, Inc. Fragmentation methods for mass spectrometry
GB2390935A (en) * 2002-07-16 2004-01-21 Anatoli Nicolai Verentchikov Time-nested mass analysis using a TOF-TOF tandem mass spectrometer
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
AU2003294165A1 (en) 2002-11-22 2004-06-18 Caprion Pharmaceuticals, Inc. Constellation mapping and uses thereof
US8507285B2 (en) * 2003-03-13 2013-08-13 Agilent Technologies, Inc. Methods and devices for identifying biopolymers using mass spectroscopy
JP4229732B2 (ja) * 2003-03-19 2009-02-25 日本電子株式会社 飛行時間型質量分析計
GB2402260B (en) * 2003-05-30 2006-05-24 Thermo Finnigan Llc All mass MS/MS method and apparatus
US6992283B2 (en) * 2003-06-06 2006-01-31 Micromass Uk Limited Mass spectrometer
JP4275545B2 (ja) * 2004-02-17 2009-06-10 株式会社日立ハイテクノロジーズ 質量分析装置
ATE479895T1 (de) * 2004-03-12 2010-09-15 Univ Virginia Elektronentransferdissoziation zur biopolymer- sequenzanalyse
CA2501003C (en) 2004-04-23 2009-05-19 F. Hoffmann-La Roche Ag Sample analysis to provide characterization data
DE102004028419B4 (de) * 2004-06-11 2011-06-22 Bruker Daltonik GmbH, 28359 Massenspektrometer und Reaktionszelle für Ionen-Ionen-Reaktionen
WO2006014984A1 (en) * 2004-07-27 2006-02-09 Ionwerks, Inc. Multiplex data acquisition modes for ion mobility-mass spectrometry
DE112005002484B4 (de) * 2004-10-08 2022-12-22 The University Of Virginia Patent Foundation Simultane Sequenzanalyse von Amino- und Carboxy-Endgruppen
GB0424426D0 (en) * 2004-11-04 2004-12-08 Micromass Ltd Mass spectrometer
GB0425426D0 (en) * 2004-11-18 2004-12-22 Micromass Ltd Mass spectrometer
GB0522933D0 (en) * 2005-11-10 2005-12-21 Micromass Ltd Mass spectrometer

Also Published As

Publication number Publication date
JP2009516903A (ja) 2009-04-23
GB2432712B (en) 2007-12-27
GB0523812D0 (en) 2006-01-04
EP1952423A2 (en) 2008-08-06
US7928363B2 (en) 2011-04-19
GB2432712A (en) 2007-05-30
WO2007060427A2 (en) 2007-05-31
CA2628926A1 (en) 2007-05-31
WO2007060427A3 (en) 2008-05-08
US20090014639A1 (en) 2009-01-15
JP4778564B2 (ja) 2011-09-21

Similar Documents

Publication Publication Date Title
CA2628926C (en) Mass spectrometer
US10083825B2 (en) Mass spectrometer with bypass of a fragmentation device
EP2016612B1 (en) Mass spectrometer
US9779929B2 (en) Method of screening a sample for the presence of one or more known compounds of interest and a mass spectrometer performing this method
EP2056334B1 (en) Collision cell for mass spectrometer
US12057303B2 (en) Optimised targeted analysis
CA2628924C (en) Mass spectrometer
CA2628927C (en) Mass spectrometer

Legal Events

Date Code Title Description
EEER Examination request