CA2620685A1 - Pharmaceutical composition comprising an iron chelator - Google Patents
Pharmaceutical composition comprising an iron chelator Download PDFInfo
- Publication number
- CA2620685A1 CA2620685A1 CA002620685A CA2620685A CA2620685A1 CA 2620685 A1 CA2620685 A1 CA 2620685A1 CA 002620685 A CA002620685 A CA 002620685A CA 2620685 A CA2620685 A CA 2620685A CA 2620685 A1 CA2620685 A1 CA 2620685A1
- Authority
- CA
- Canada
- Prior art keywords
- composition
- active compound
- particles
- sustained release
- phospholipid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 16
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- 150000003904 phospholipids Chemical class 0.000 claims abstract description 40
- 239000004480 active ingredient Substances 0.000 claims abstract description 17
- 229940075525 iron chelating agent Drugs 0.000 claims abstract description 17
- 239000000797 iron chelating agent Substances 0.000 claims abstract description 17
- 238000007911 parenteral administration Methods 0.000 claims abstract description 17
- 238000011282 treatment Methods 0.000 claims abstract description 16
- UBQYURCVBFRUQT-UHFFFAOYSA-N N-benzoyl-Ferrioxamine B Chemical compound CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN UBQYURCVBFRUQT-UHFFFAOYSA-N 0.000 claims description 60
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US71334705P | 2005-09-02 | 2005-09-02 | |
| EP05108071 | 2005-09-02 | ||
| EP05108071.1 | 2005-09-02 | ||
| US60/713,347 | 2005-09-02 | ||
| PCT/EP2006/065952 WO2007026028A2 (en) | 2005-09-02 | 2006-09-04 | Pharmaceutical composition comprising an iron chelator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2620685A1 true CA2620685A1 (en) | 2007-03-08 |
Family
ID=36305265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002620685A Abandoned CA2620685A1 (en) | 2005-09-02 | 2006-09-04 | Pharmaceutical composition comprising an iron chelator |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1937215A2 (de) |
| JP (1) | JP2009507006A (de) |
| KR (1) | KR20080044845A (de) |
| CN (1) | CN101252913A (de) |
| AU (1) | AU2006286445A1 (de) |
| BR (1) | BRPI0615349A2 (de) |
| CA (1) | CA2620685A1 (de) |
| WO (1) | WO2007026028A2 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2000134A1 (de) * | 2007-06-06 | 2008-12-10 | Neuraxo Biopharmaceuticals GmbH | Verwendung einer Substanz zur Behandlung von Verletzungen des peripheren Nervensystems |
| WO2014036414A2 (en) | 2012-08-30 | 2014-03-06 | The Board Of Trustees Of The Leland Stanford Junior University | Iron chelators and use thereof for reducing transplant failure |
| EP3177269A4 (de) | 2014-08-04 | 2018-02-28 | Zoneone Pharma, Inc. | Fernladung von schwach wasserlöslichen medikamenten in lipidvesikel |
| WO2016025611A2 (en) * | 2014-08-13 | 2016-02-18 | Zoneone Pharma, Inc. | Pharmaceutical formulations of chelating agents as a metal removal treatment system |
| MX2018009662A (es) * | 2016-02-11 | 2018-09-11 | Chevion Mordechai | Metodo y composicion farmaceutica para tratamiento de neurodegeneracion. |
| EP3585385A4 (de) * | 2017-02-27 | 2020-12-30 | The University of Adelaide | Verfahren und produkte zur verringerung von adhäsionen |
| US11479532B2 (en) | 2017-06-23 | 2022-10-25 | University Of South Florida | 5-aminolevulinate synthase inhibitors and methods of use thereof |
| CN110464717B (zh) * | 2019-09-23 | 2022-02-18 | 张建国 | 一种2,4-二羟基苯甲酸在制备降低血糖的药物的应用 |
| CN114652844B (zh) * | 2022-04-13 | 2023-10-20 | 南京大学 | 一种基于仿生学设计的纳米组装材料的制备方法及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023087A (en) * | 1986-02-10 | 1991-06-11 | Liposome Technology, Inc. | Efficient method for preparation of prolonged release liposome-based drug delivery system |
| US5043166A (en) * | 1987-01-09 | 1991-08-27 | Hadasit Medical Research, Inc. | Liposome/anthraquinone drug composition and method |
| EP0878480A1 (de) * | 1997-05-14 | 1998-11-18 | H.W. Prof. Dr. Müller | Verfahren zur Förderung der Nerven-Regenerierung |
| IL130324A0 (en) * | 1999-06-07 | 2000-06-01 | Yeda Res & Dev | Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators |
| US8029795B2 (en) * | 1999-12-30 | 2011-10-04 | Gwathmey, Inc. | Targeted iron chelator delivery system |
-
2006
- 2006-09-04 EP EP06793171A patent/EP1937215A2/de not_active Withdrawn
- 2006-09-04 CA CA002620685A patent/CA2620685A1/en not_active Abandoned
- 2006-09-04 BR BRPI0615349-6A patent/BRPI0615349A2/pt not_active Application Discontinuation
- 2006-09-04 AU AU2006286445A patent/AU2006286445A1/en not_active Abandoned
- 2006-09-04 KR KR1020087004966A patent/KR20080044845A/ko not_active Application Discontinuation
- 2006-09-04 CN CNA2006800318484A patent/CN101252913A/zh active Pending
- 2006-09-04 JP JP2008528537A patent/JP2009507006A/ja active Pending
- 2006-09-04 WO PCT/EP2006/065952 patent/WO2007026028A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| CN101252913A (zh) | 2008-08-27 |
| EP1937215A2 (de) | 2008-07-02 |
| WO2007026028A2 (en) | 2007-03-08 |
| BRPI0615349A2 (pt) | 2011-05-17 |
| AU2006286445A1 (en) | 2007-03-08 |
| WO2007026028A3 (en) | 2007-06-14 |
| KR20080044845A (ko) | 2008-05-21 |
| JP2009507006A (ja) | 2009-02-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |