CA2620582C - Methods of altering an immune response induced by cpg oligodeoxynucleotides - Google Patents

Methods of altering an immune response induced by cpg oligodeoxynucleotides Download PDF

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CA2620582C
CA2620582C CA2620582A CA2620582A CA2620582C CA 2620582 C CA2620582 C CA 2620582C CA 2620582 A CA2620582 A CA 2620582A CA 2620582 A CA2620582 A CA 2620582A CA 2620582 C CA2620582 C CA 2620582C
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cxcl16
agent
activity
expression
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French (fr)
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CA2620582A1 (en
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Dennis M. Klinman
Mayda Gursel
Ihsan Gursel
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US Department of Health and Human Services
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
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    • C12N15/09—Recombinant DNA-technology
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CA2620582A 2005-08-31 2006-08-28 Methods of altering an immune response induced by cpg oligodeoxynucleotides Expired - Fee Related CA2620582C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US71354705P 2005-08-31 2005-08-31
US60/713,547 2005-08-31
PCT/US2006/033774 WO2007027718A1 (en) 2005-08-31 2006-08-28 Methods of altering an immune response induced by cpg oligodeoxynucleotides

Publications (2)

Publication Number Publication Date
CA2620582A1 CA2620582A1 (en) 2007-03-08
CA2620582C true CA2620582C (en) 2015-11-10

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CA2620582A Expired - Fee Related CA2620582C (en) 2005-08-31 2006-08-28 Methods of altering an immune response induced by cpg oligodeoxynucleotides

Country Status (6)

Country Link
US (2) US7892569B2 (OSRAM)
EP (1) EP1929014B1 (OSRAM)
JP (1) JP5481068B2 (OSRAM)
AU (1) AU2006284889B2 (OSRAM)
CA (1) CA2620582C (OSRAM)
WO (1) WO2007027718A1 (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6207646B1 (en) * 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6977245B2 (en) * 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
AU4343700A (en) 1999-04-12 2000-11-14 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Oligodeoxynucleotide and its use to induce an immune response
EP1322655B1 (en) * 2000-01-14 2007-11-14 The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services Oligodeoxynucleotide and its use to induce an immune response
AU2004275876B2 (en) * 2003-09-25 2011-03-31 Coley Pharmaceutical Gmbh Nucleic acid-lipophilic conjugates
WO2010067262A1 (en) 2008-12-09 2010-06-17 Pfizer Inc. Immunostimulatory oligonucleotides
US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
AU2010229835B2 (en) 2009-03-25 2015-01-15 The Board Of Regents Of The University Of Texas System Compositions for stimulation of mammalian innate immune resistance to pathogens
KR101822444B1 (ko) 2010-07-08 2018-01-26 가켄 세이야쿠 가부시키가이샤 N-히드록시포름아미드 유도체 및 그를 함유하는 의약
CN103555726B (zh) * 2013-10-14 2015-05-13 中国科学院海洋研究所 一种含有未甲基化CpG的DNA序列(CpG-DNA)及其应用
EP3164113B1 (en) 2014-06-04 2019-03-27 Exicure, Inc. Multivalent delivery of immune modulators by liposomal spherical nucleic acids for prophylactic or therapeutic applications
WO2016044839A2 (en) 2014-09-19 2016-03-24 The Board Of Regents Of The University Of Texas System Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
US11696954B2 (en) * 2017-04-28 2023-07-11 Exicure Operating Company Synthesis of spherical nucleic acids using lipophilic moieties
EP3752194A4 (en) 2018-02-13 2022-03-16 Checkmate Pharmaceuticals, Inc. COMPOSITIONS AND METHODS FOR TUMOR IMMUNOTHERAPY
SG11202009647VA (en) 2018-04-09 2020-10-29 Checkmate Pharmaceuticals Packaging oligonucleotides into virus-like particles
EP4637788A1 (en) 2022-12-19 2025-10-29 Six Therapeutics Inc. Compositions and methods of using cpg oligonucleotides

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02138868A (ja) * 1988-11-18 1990-05-28 Eisai Co Ltd 男性不妊症の診断試薬
CA2328602A1 (en) 1998-05-06 1999-11-11 University Of Iowa Research Foundation Methods for the prevention and treatment of parasitic infections and related diseases using cpg oligonucleotides
AU4343700A (en) * 1999-04-12 2000-11-14 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Oligodeoxynucleotide and its use to induce an immune response
NZ517928A (en) * 1999-09-27 2004-09-24 Coley Pharm Gmbh Methods related to immunostimulatory nucleic acid-induced interferon

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Publication number Publication date
EP1929014A1 (en) 2008-06-11
US7892569B2 (en) 2011-02-22
EP1929014B1 (en) 2014-08-13
JP5481068B2 (ja) 2014-04-23
US20080249056A1 (en) 2008-10-09
JP2009506122A (ja) 2009-02-12
US20110110883A1 (en) 2011-05-12
US8470342B2 (en) 2013-06-25
AU2006284889A1 (en) 2007-03-08
CA2620582A1 (en) 2007-03-08
WO2007027718A1 (en) 2007-03-08
AU2006284889B2 (en) 2011-08-18

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