CA2619937C - Highly crystalline polyethylene - Google Patents

Highly crystalline polyethylene Download PDF

Info

Publication number
CA2619937C
CA2619937C CA 2619937 CA2619937A CA2619937C CA 2619937 C CA2619937 C CA 2619937C CA 2619937 CA2619937 CA 2619937 CA 2619937 A CA2619937 A CA 2619937A CA 2619937 C CA2619937 C CA 2619937C
Authority
CA
Canada
Prior art keywords
polymeric blend
polymeric
electron beam
temperature
beam radiation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA 2619937
Other languages
English (en)
French (fr)
Other versions
CA2619937A1 (en
Inventor
Orhun K. Muratoglu
Ebru Oral
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of CA2619937A1 publication Critical patent/CA2619937A1/en
Application granted granted Critical
Publication of CA2619937C publication Critical patent/CA2619937C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/24—Crosslinking, e.g. vulcanising, of macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F110/00—Homopolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond
    • C08F110/02—Ethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/20—Compounding polymers with additives, e.g. colouring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/28—Treatment by wave energy or particle radiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/15—Heterocyclic compounds having oxygen in the ring
    • C08K5/151—Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
    • C08K5/1545—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/04—Homopolymers or copolymers of ethene
    • C08J2323/06—Polyethene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/08—Polyethers derived from hydroxy compounds or from their metallic derivatives
    • C08J2371/10—Polyethers derived from hydroxy compounds or from their metallic derivatives from phenols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2377/00—Characterised by the use of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Derivatives of such polymers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/08—Heat treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2207/00—Properties characterising the ingredient of the composition
    • C08L2207/06—Properties of polyethylene
    • C08L2207/068—Ultra high molecular weight polyethylene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/04—Homopolymers or copolymers of ethene
    • C08L23/06—Polyethene
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31678—Of metal
    • Y10T428/31692—Next to addition polymer from unsaturated monomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Materials For Medical Uses (AREA)
CA 2619937 2005-08-22 2006-08-18 Highly crystalline polyethylene Active CA2619937C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70979605P 2005-08-22 2005-08-22
US60/709,796 2005-08-22
PCT/US2006/032321 WO2007024684A2 (en) 2005-08-22 2006-08-18 Highly crystalline polyethylene

Publications (2)

Publication Number Publication Date
CA2619937A1 CA2619937A1 (en) 2007-03-01
CA2619937C true CA2619937C (en) 2014-10-14

Family

ID=37772200

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2619937 Active CA2619937C (en) 2005-08-22 2006-08-18 Highly crystalline polyethylene

Country Status (6)

Country Link
US (3) US8425815B2 (cg-RX-API-DMAC7.html)
EP (5) EP2441780A1 (cg-RX-API-DMAC7.html)
JP (1) JP5452920B2 (cg-RX-API-DMAC7.html)
AU (1) AU2006283596B2 (cg-RX-API-DMAC7.html)
CA (1) CA2619937C (cg-RX-API-DMAC7.html)
WO (1) WO2007024684A2 (cg-RX-API-DMAC7.html)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
WO2005074619A2 (en) * 2004-02-03 2005-08-18 Massachusetts General Hospital Highly crystalline cross-linked oxidation-resistant polyethylene
US7344672B2 (en) 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US8262976B2 (en) * 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
EP2277561B1 (en) * 2005-08-18 2012-09-19 Zimmer GmbH Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles
EP2441780A1 (en) * 2005-08-22 2012-04-18 The General Hospital Corporation d/b/a Massachusetts General Hospital Highly Crystalline Polyethylene
JP2010529213A (ja) 2007-03-02 2010-08-26 ザ・ジェネラル・ホスピタル・コーポレイション 酸化防止剤含有ポリマーの架橋
ATE544476T1 (de) * 2007-04-10 2012-02-15 Zimmer Inc Antioxidans-stabilisiertes vernetztes ultrahochmolekulares polyethylen für anwendungen in medizinprodukten
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
US8641959B2 (en) 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
WO2009032909A2 (en) * 2007-09-04 2009-03-12 Smith & Nephew Orthopaedics Ag Ultra high molecular weight polyethylene for bearing surfaces
CA2712559C (en) 2008-01-30 2015-03-31 Zimmer, Inc. Orthopedic component of low stiffness
CN102216381B (zh) * 2008-04-24 2016-06-15 麦德托尼克公司 可再水化的多糖颗粒和海绵体
AU2008356467A1 (en) * 2008-05-13 2009-11-19 Smith & Nephew Orthopaedics Ag Oxidation resistant highly-crosslinked UHMWPE
EP2346941A1 (en) 2008-11-20 2011-07-27 Zimmer GmbH Polyethylene materials
US8933145B2 (en) 2009-02-20 2015-01-13 The General Hospital Corporation High temperature melting
JP4806717B2 (ja) * 2009-06-25 2011-11-02 株式会社沖データ 画像処理システム
DE102009033681A1 (de) * 2009-07-17 2011-02-03 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Vorrichtung zur Herstellung von Kunststoff-Formteilen und deren Verwendung
GB0922339D0 (en) 2009-12-21 2010-02-03 Mcminn Derek J W Acetabular cup prothesis and introducer thereof
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
CN103755990A (zh) 2011-01-13 2014-04-30 积水化学工业株式会社 高分子成形品的制造方法及高分子成形品
WO2013138240A1 (en) * 2012-03-12 2013-09-19 Colorado State University Research Foundation Glycosaminoglycan and synthetic polymer materials for blood-contacting applications
US10266684B2 (en) 2012-03-12 2019-04-23 Colorado State University Research Foundation Glycosaminoglycan and synthetic polymer materials for blood-contacting applications
WO2013174782A1 (en) * 2012-05-22 2013-11-28 Total Research & Technology Feluy Process for preparing a polymeric product
EP2792471B1 (en) * 2013-04-16 2018-01-31 Stratec Consumables GmbH Polymer parts
US9429860B2 (en) 2013-05-22 2016-08-30 Canon Kabushiki Kaisha Toner production method
US9586370B2 (en) 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
EP3052562B1 (en) 2013-10-01 2017-11-08 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
EP3058017A4 (en) 2013-10-17 2017-10-04 The General Hospital Corporation Peroxide cross-linking and high temperature melting
WO2015138137A1 (en) * 2014-03-12 2015-09-17 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
US20150368375A1 (en) 2014-06-24 2015-12-24 Biomet Manufacturing, Llc Methods For Making Crosslinked Ultra High Molecular Weight Polyethylene
US10265891B2 (en) 2014-12-03 2019-04-23 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
US20180250099A1 (en) 2015-11-02 2018-09-06 3M Innovative Properties Company Orthodontic appliance having continuous shape memory
WO2017083476A1 (en) 2015-11-12 2017-05-18 The General Hospital Corporation Methods of making therapeutic polymeric material
AU2017214566A1 (en) 2016-02-05 2018-08-23 The General Hospital Corporation Drug eluting polymer composed of biodegradable polymers applied to surface of medical device
WO2017192347A1 (en) 2016-05-02 2017-11-09 The General Hospital Corporation Implant surfaces for pain control
WO2019046243A2 (en) 2017-08-29 2019-03-07 The General Hospital Corporation UV-INITIATED REACTIONS IN POLYMERIC MATERIALS
US11376128B2 (en) 2018-12-31 2022-07-05 Depuy Ireland Unlimited Company Acetabular orthopaedic prosthesis and method
US12171666B2 (en) 2019-12-10 2024-12-24 Depuy Ireland Unlimited Company Metal reinforced acetabular shell liner
US11291549B2 (en) 2019-12-11 2022-04-05 Depuy Ireland Unlimited Company Ceramic acetabular shell liners with augments
US11628066B2 (en) 2019-12-11 2023-04-18 Depuy Ireland Unlimited Company Ceramic acetabular shell liner with a metal ring having a lead-in surface
US11970600B2 (en) 2021-03-31 2024-04-30 The General Hospital Corporation Di-cumyl peroxide crosslinking of UHMWPE
US12042389B2 (en) 2021-04-30 2024-07-23 Depuy Ireland Unlimited Company Apparatus and method for installing an acetabular liner on an acetabular cup
US12376964B2 (en) 2021-04-30 2025-08-05 Depuy Ireland Unlimited Company Apparatus and method for locking an acetabular liner to an acetabular cup

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2104960T3 (es) 1991-11-27 1997-10-16 Du Pont Polietileno lineal de peso molecular ultraalto y procedimiento de fabricacion.
US6371985B1 (en) 1995-03-09 2002-04-16 Robert S. Goldberg Prostheses restrained by immediate attachment while ingrowth proceeds naturally over time
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
RU2211008C2 (ru) 1996-02-13 2003-08-27 Массачусетс Институт Оф Текнолоджи Протезные устройства из полиэтилена сверхвысокой молекулярной массы, обработанного облучением и плавлением
US5827904A (en) 1996-09-27 1998-10-27 Hahn; David Medical implant composition
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
WO1998016258A1 (en) * 1996-10-15 1998-04-23 The Orthopaedic Hospital Wear resistant surface-gradient cross-linked polyethylene
FI110063B (fi) * 1998-12-11 2002-11-29 Antti Yli-Urpo Uusi bioaktiivinen tuote ja sen käyttö
SE9900519D0 (sv) * 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6620198B2 (en) * 1999-10-07 2003-09-16 Exactech, Inc. Composite bearing inserts for total knee joints
AU6108301A (en) 2000-04-27 2001-11-07 Orthopaedic Hospital Oxidation-resistant and wear-resistant polyethylenes for human joint replacements and methods for making them
US6818172B2 (en) * 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
WO2002026464A1 (en) 2000-09-29 2002-04-04 Depuy Orthopaedics, Inc. Supercritical fluid treatment of irradiated polyethylene
CA2471771C (en) 2002-01-04 2012-01-03 Massachusetts General Hospital A high modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt
WO2004000159A2 (en) 2002-06-21 2003-12-31 Massachusetts General Hospital Metal back or mesh crosslinking
EP2671538A1 (en) * 2003-01-16 2013-12-11 Massachusetts General Hospital Methods For Making Oxidation Resistant Polymeric Material
WO2005074619A2 (en) * 2004-02-03 2005-08-18 Massachusetts General Hospital Highly crystalline cross-linked oxidation-resistant polyethylene
US7833452B2 (en) * 2004-05-11 2010-11-16 The General Hospital Corporation Method for making oxidation resistant polymeric material
EP2441780A1 (en) 2005-08-22 2012-04-18 The General Hospital Corporation d/b/a Massachusetts General Hospital Highly Crystalline Polyethylene
US8872847B2 (en) 2008-08-28 2014-10-28 Google Inc. Architectures and methods for creating and representing time-dependent imagery
WO2013126592A2 (en) 2012-02-21 2013-08-29 Cameron International Corporation Well tree hub and interface for retrievable processing modules

Also Published As

Publication number Publication date
EP2208739A1 (en) 2010-07-21
US20070267030A1 (en) 2007-11-22
US8420000B2 (en) 2013-04-16
EP2441780A1 (en) 2012-04-18
JP2009504897A (ja) 2009-02-05
US20100082101A1 (en) 2010-04-01
WO2007024684A2 (en) 2007-03-01
US9273189B2 (en) 2016-03-01
AU2006283596B2 (en) 2012-10-11
WO2007024684A3 (en) 2007-11-15
EP2441781A1 (en) 2012-04-18
US8425815B2 (en) 2013-04-23
JP5452920B2 (ja) 2014-03-26
EP2441782A1 (en) 2012-04-18
EP1924614A4 (en) 2009-08-26
US20130197120A1 (en) 2013-08-01
CA2619937A1 (en) 2007-03-01
EP1924614A2 (en) 2008-05-28
AU2006283596A1 (en) 2007-03-01

Similar Documents

Publication Publication Date Title
CA2619937C (en) Highly crystalline polyethylene
EP2291417B1 (en) Oxidation resistant highly-crosslinked uhmwpe
CA2429930C (en) Sequentially cross-linked polyethylene
US7205051B2 (en) Medical implant or medical implant part
EP2792373B1 (en) Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles
CN102307945B (zh) 聚乙烯材料
US20140024736A1 (en) Polymer articles having chemically bonded agents and methods of making the same
CA2554777A1 (en) Highly crystalline cross-linked oxidation-resistant polyethylene
JP2009504897A5 (cg-RX-API-DMAC7.html)
WO2004064618B1 (en) Methods for making oxidation resistant polymeric material
JP2017201037A (ja) 関節面用の超高分子量ポリエチレン
WO2008101073A2 (en) Crosslinked polymers
JP5735443B2 (ja) 超高分子量ポリエチレン物品および超高分子量ポリエチレン物品を形成する方法
JP5969637B2 (ja) 超高分子量ポリエチレン物品および超高分子量ポリエチレン物品を形成する方法
EP1312636A1 (en) Method of crosslinking polyolefins
US8343230B2 (en) Orthopaedic bearing material
EP2921186B1 (en) Annealing method for cross-linked polyethylene
AU2003230479A1 (en) A process for radiation treatment of ethylene polymers
WO2007068216A1 (en) Method of modification of ultrahigh-molecular-weight polyethylene for manufacture of joint replacements with increased lifetime
CA2788687A1 (en) Ultra high molecular weight polyethylene articles and methods of forming ultra high molecular weight polyethylene articles

Legal Events

Date Code Title Description
EEER Examination request