CA2607155C - Pharmaceutical compositions comprising casein derived peptides and methods of use thereof - Google Patents

Pharmaceutical compositions comprising casein derived peptides and methods of use thereof Download PDF

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Publication number
CA2607155C
CA2607155C CA2607155A CA2607155A CA2607155C CA 2607155 C CA2607155 C CA 2607155C CA 2607155 A CA2607155 A CA 2607155A CA 2607155 A CA2607155 A CA 2607155A CA 2607155 C CA2607155 C CA 2607155C
Authority
CA
Canada
Prior art keywords
casein
peptide
derived
seq
milk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2607155A
Other languages
English (en)
French (fr)
Other versions
CA2607155A1 (en
Inventor
Jose Mario Iscovich
Nissim Silanikove
Javier Iscovich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mileutis Ltd
Agricultural Research Organization of Israel Ministry of Agriculture
Original Assignee
Mileutis Ltd
Agricultural Research Organization of Israel Ministry of Agriculture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mileutis Ltd, Agricultural Research Organization of Israel Ministry of Agriculture filed Critical Mileutis Ltd
Publication of CA2607155A1 publication Critical patent/CA2607155A1/en
Application granted granted Critical
Publication of CA2607155C publication Critical patent/CA2607155C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nutrition Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CA2607155A 2005-05-02 2006-05-02 Pharmaceutical compositions comprising casein derived peptides and methods of use thereof Expired - Lifetime CA2607155C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US67629205P 2005-05-02 2005-05-02
US60/676,292 2005-05-02
US68869705P 2005-06-09 2005-06-09
US60/688,697 2005-06-09
PCT/IL2006/000524 WO2006117784A2 (en) 2005-05-02 2006-05-02 Pharmaceutical compositions comprising casein derived peptides and methods of use thereof

Publications (2)

Publication Number Publication Date
CA2607155A1 CA2607155A1 (en) 2006-11-09
CA2607155C true CA2607155C (en) 2016-09-13

Family

ID=37308387

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2607155A Expired - Lifetime CA2607155C (en) 2005-05-02 2006-05-02 Pharmaceutical compositions comprising casein derived peptides and methods of use thereof

Country Status (18)

Country Link
US (2) US7968513B2 (enExample)
EP (1) EP1890720B1 (enExample)
JP (1) JP5247429B2 (enExample)
KR (2) KR20130122979A (enExample)
CN (1) CN106421749A (enExample)
AR (1) AR059462A1 (enExample)
AU (1) AU2006242842B2 (enExample)
BR (1) BRPI0611301A2 (enExample)
CA (1) CA2607155C (enExample)
CL (1) CL2011000039A1 (enExample)
EA (1) EA016039B1 (enExample)
ES (1) ES2400511T3 (enExample)
IN (1) IN2014DN10391A (enExample)
MX (1) MX2007013866A (enExample)
NZ (1) NZ563936A (enExample)
PL (1) PL1890720T3 (enExample)
UY (1) UY29515A1 (enExample)
WO (1) WO2006117784A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY29515A1 (es) * 2005-05-02 2007-11-30 Mileutis Ltd Composiciones farmaceuticas que constan de peptidos derivados de la caseina y métodos del uso de los mismos
JP5507555B2 (ja) * 2008-06-30 2014-05-28 チョ−エー・ファーム・カンパニー・リミテッド 豚のαＳ１カゼイン遺伝子、そのプロモーター、及びその用途
US8133916B1 (en) 2009-03-10 2012-03-13 Amelgo, LLC Control of milk production and mammary involution
US20110017323A1 (en) * 2009-07-22 2011-01-27 Ewa Herbst Method and apparatus for inline testing
CA2797658C (en) * 2010-04-21 2021-06-08 Mileutis Ltd. Casein peptide for use in the treatment of uterine infections
FR2971423B1 (fr) * 2011-02-15 2014-01-10 Ceva Sante Animale Composition veterinaire antiprolactinique destinee aux ruminants
ES2759980T3 (es) * 2012-03-19 2020-05-12 Mileutis Ltd Péptidos para el manejo de la lactación
EP2810695A1 (en) * 2013-06-06 2014-12-10 Ceva Sante Animale Compositions and Method for controlling infections in non-human mammals using acute phase proteins
NZ753824A (en) * 2016-11-09 2022-08-26 Charles Sturt Univ Livestock supplement and use thereof
AU2017376402B2 (en) * 2016-12-13 2021-10-28 Dsm Ip Assets B.V. PUFA salt formulations (I)
CN108017709B (zh) * 2017-12-12 2020-04-10 浙江辉肽生命健康科技有限公司 一种生物活性多肽kepmigvnqela及其制备方法和应用
US20230106635A1 (en) * 2020-02-19 2023-04-06 Perfect Day, Inc. Hypoallergenic recombinant milk proteins and compositions comprising the same
EP4329790A1 (en) * 2021-04-28 2024-03-06 Mileutis Ltd. Compositions and methods for modulating mammary disorders and conditions
CN120379680A (zh) * 2022-11-17 2025-07-25 米勒尤迪斯公司 用于调节乳腺病症和病状的组合物和方法
CN121358342A (zh) * 2023-05-16 2026-01-16 米勒尤迪斯公司 提升的乳质
WO2026159713A1 (en) * 2025-01-23 2026-07-30 Mileutis Ltd. A method of increasing milk production

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3764670A (en) * 1970-10-28 1973-10-09 Ministry Of Agriculture Polypeptidic anti-biotic substances derived from casein
FR2474829B1 (fr) * 1980-02-01 1983-09-09 Agronomique Inst Nat Rech Procede de traitement d'une matiere a base de caseine contenant des phosphocaseinates de cations monovalents ou leurs derives, produits obtenus et applications
US5405756A (en) * 1982-03-30 1995-04-11 Meiji Seika Kaisha, Ltd. Transparent acid drink containing acid-soluble casein phosphopeptide
US5015628A (en) * 1986-06-12 1991-05-14 The University Of Melbourne Anticariogenic phosphopeptides
ES2149771T3 (es) * 1991-04-19 2000-11-16 Univ Melbourne Produccion de fosfopeptidos a partir de la caseina.
US5227154A (en) * 1991-08-22 1993-07-13 The University Of Melbourne Phosphopeptides for the treatment of dental calculus
KR0140248B1 (ko) * 1995-03-23 1998-06-15 한상기 신규한 카제인 포스포펩티드, 그것을 포함하는 카제인 및 그 제조방법
AUPO566297A0 (en) * 1997-03-13 1997-04-10 University Of Melbourne, The Calcium phosphopeptide complexes
AUPP494798A0 (en) * 1998-07-29 1998-08-20 Pacific Biolink Pty Limited Protective protein formulation
AU775999B2 (en) 1999-08-24 2004-08-19 Meiji Seika Pharma Co., Ltd. Growth promoting compositions for mammals and method of promoting the growth of mammals by using the same
US6391849B1 (en) * 1999-11-19 2002-05-21 Agricultural Research Organization, The Volcani Center Method and pharmaceutical composition for disrupting lactation in a mammary gland and for treating and preventing mastitis
IL134830A0 (en) * 2000-03-01 2001-05-20 Chay 13 Medical Res Group N V Peptides and immunostimulatory and anti-bacterial pharmaceutical compositions containing them
US7666996B2 (en) * 2000-03-01 2010-02-23 Peptera Pharmaceuticals Ltd Casein derived peptides and uses thereof
JPWO2002072629A1 (ja) * 2001-03-09 2004-07-02 明治製菓株式会社 免疫増強剤
KR20070007128A (ko) 2004-03-01 2007-01-12 펩테라 파마슈티컬스 엘티디. 카제인 파생 펩타이드들과 그의 치료적 사용들
UY29515A1 (es) * 2005-05-02 2007-11-30 Mileutis Ltd Composiciones farmaceuticas que constan de peptidos derivados de la caseina y métodos del uso de los mismos

Also Published As

Publication number Publication date
JP5247429B2 (ja) 2013-07-24
EA200702401A1 (ru) 2008-08-29
WO2006117784A2 (en) 2006-11-09
IN2014DN10391A (enExample) 2015-08-14
BRPI0611301A2 (pt) 2010-08-31
US7968513B2 (en) 2011-06-28
EA016039B1 (ru) 2012-01-30
JP2008540399A (ja) 2008-11-20
NZ563936A (en) 2010-03-26
CL2011000039A1 (es) 2011-06-10
CA2607155A1 (en) 2006-11-09
EP1890720A2 (en) 2008-02-27
WO2006117784A3 (en) 2009-05-22
US20090069218A1 (en) 2009-03-12
US8338363B2 (en) 2012-12-25
ES2400511T3 (es) 2013-04-10
US20110212886A1 (en) 2011-09-01
KR20080012933A (ko) 2008-02-12
EP1890720B1 (en) 2013-01-09
KR101340676B1 (ko) 2013-12-18
CN106421749A (zh) 2017-02-22
AU2006242842A1 (en) 2006-11-09
PL1890720T3 (pl) 2013-06-28
EP1890720A4 (en) 2010-05-26
AR059462A1 (es) 2008-04-09
AU2006242842B2 (en) 2011-12-08
KR20130122979A (ko) 2013-11-11
UY29515A1 (es) 2007-11-30
MX2007013866A (es) 2008-04-07

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