CA2602442A1 - Ep2 receptor agonists for treating glaucoma - Google Patents

Ep2 receptor agonists for treating glaucoma Download PDF

Info

Publication number
CA2602442A1
CA2602442A1 CA002602442A CA2602442A CA2602442A1 CA 2602442 A1 CA2602442 A1 CA 2602442A1 CA 002602442 A CA002602442 A CA 002602442A CA 2602442 A CA2602442 A CA 2602442A CA 2602442 A1 CA2602442 A1 CA 2602442A1
Authority
CA
Canada
Prior art keywords
group
formula
represented
carbon atoms
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002602442A
Other languages
English (en)
French (fr)
Inventor
David F. Woodward
June Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2602442A1 publication Critical patent/CA2602442A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/70Sulfur atoms
    • C07D213/71Sulfur atoms to which a second hetero atom is attached
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
CA002602442A 2005-08-29 2006-08-21 Ep2 receptor agonists for treating glaucoma Abandoned CA2602442A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US71258605P 2005-08-29 2005-08-29
US60/712,586 2005-08-29
US11/472,145 US7696235B2 (en) 2005-08-29 2006-06-21 EP2 receptor agonists for treating glaucoma
US11/472,145 2006-06-21
PCT/US2006/032670 WO2007027468A1 (en) 2005-08-29 2006-08-21 Ep2 receptor agonists for treating glaucoma

Publications (1)

Publication Number Publication Date
CA2602442A1 true CA2602442A1 (en) 2007-03-08

Family

ID=37529305

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002602442A Abandoned CA2602442A1 (en) 2005-08-29 2006-08-21 Ep2 receptor agonists for treating glaucoma

Country Status (7)

Country Link
US (1) US7696235B2 (cg-RX-API-DMAC7.html)
EP (1) EP1919870A1 (cg-RX-API-DMAC7.html)
JP (1) JP2009506113A (cg-RX-API-DMAC7.html)
AU (1) AU2006285177A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0615245A2 (cg-RX-API-DMAC7.html)
CA (1) CA2602442A1 (cg-RX-API-DMAC7.html)
WO (1) WO2007027468A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2659184C (en) * 2006-07-28 2012-02-21 Pfizer Products Inc. Ep2 agonists
US8063240B2 (en) 2007-11-14 2011-11-22 Cayman Chemical Company, Incorporated Prostaglandin E1 and E2 analogs for the treatment of various medical conditions
US8648097B2 (en) * 2008-03-12 2014-02-11 Ube Industries, Ltd. Pyridylaminoacetic acid compound
ES2564010T3 (es) 2009-03-30 2016-03-17 Ube Industries, Ltd. Composición farmacéutica para tratar o prevenir el glaucoma
AU2010293410A1 (en) * 2009-09-11 2012-05-03 Ube Industries, Ltd. Substituted carbonyl compounds
JPWO2011030864A1 (ja) * 2009-09-11 2013-02-07 宇部興産株式会社 アニリン化合物
WO2011030871A1 (ja) * 2009-09-11 2011-03-17 宇部興産株式会社 N-置換ヘテロアリール化合物
CN109072186B (zh) 2016-03-04 2023-06-23 莱兰斯坦福初级大学评议会 利用前列腺素e2进行肌肉再生的组合物和方法
KR102698911B1 (ko) 2017-06-09 2024-08-23 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 근육 질환을 예방하거나 치료하기 위한 조성물 및 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA67754C2 (uk) * 1997-10-10 2004-07-15 Пфайзер, Інк. Агоністи простагландину, фармацевтична композиція на їх основі (варіанти), спосіб нарощення та збереження кісткової маси у хребетних та спосіб лікування (варіанти)
US20020161026A1 (en) * 2000-11-07 2002-10-31 Paralkar Vishwas M. Combination therapies for the stimulation of bone growth
EP1601351A1 (en) 2003-03-04 2005-12-07 Pfizer Products Inc. Use of ep2 selective receptor agonists in medical treatment
WO2005027931A1 (en) * 2003-09-19 2005-03-31 Pfizer Products Inc. Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and an ep2 or ep4 selective agonist

Also Published As

Publication number Publication date
US7696235B2 (en) 2010-04-13
EP1919870A1 (en) 2008-05-14
BRPI0615245A2 (pt) 2011-05-10
AU2006285177A1 (en) 2007-03-08
WO2007027468A1 (en) 2007-03-08
US20070049625A1 (en) 2007-03-01
JP2009506113A (ja) 2009-02-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20130521