CA2599205A1 - Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer - Google Patents

Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer Download PDF

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Publication number
CA2599205A1
CA2599205A1 CA002599205A CA2599205A CA2599205A1 CA 2599205 A1 CA2599205 A1 CA 2599205A1 CA 002599205 A CA002599205 A CA 002599205A CA 2599205 A CA2599205 A CA 2599205A CA 2599205 A1 CA2599205 A1 CA 2599205A1
Authority
CA
Canada
Prior art keywords
group
polar
npl
optionally substituted
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002599205A
Other languages
English (en)
French (fr)
Inventor
Gregory N. Tew
Lachelle S. Arnt
William F. Degrado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
University of Massachusetts Amherst
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2599205A1 publication Critical patent/CA2599205A1/en
Abandoned legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002599205A 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer Abandoned CA2599205A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65609205P 2005-02-25 2005-02-25
US60/656,092 2005-02-25
PCT/US2006/006487 WO2006093813A2 (en) 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer

Publications (1)

Publication Number Publication Date
CA2599205A1 true CA2599205A1 (en) 2006-09-08

Family

ID=36941658

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002599205A Abandoned CA2599205A1 (en) 2005-02-25 2006-02-24 Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer

Country Status (8)

Country Link
US (1) US20060241052A1 (enExample)
EP (5) EP2298074A3 (enExample)
JP (1) JP2008531585A (enExample)
KR (1) KR20080004475A (enExample)
AU (1) AU2006218805A1 (enExample)
CA (1) CA2599205A1 (enExample)
TW (2) TW201231063A (enExample)
WO (1) WO2006093813A2 (enExample)

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CA2789997A1 (en) * 2001-03-08 2002-12-19 William F. Degrado Facially amphiphilic polymers an anti-infective agents
EP2471525A3 (en) 2003-03-17 2012-12-12 The Trustees Of The University Of Pennsylvania Facially amphiphllic polymers and oligomers and uses thereof
TWI388280B (zh) 2004-01-23 2013-03-11 Univ Pennsylvania 面上兩性之聚芳基和聚芳炔基聚合物與寡聚物及其用途
CN102653515A (zh) 2004-06-15 2012-09-05 宝利麦迪克斯股份有限公司 聚阳离子化合物及其用途
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
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CN102164892A (zh) 2008-07-28 2011-08-24 波利梅伊公司 抗疟疾化合物
US8278309B2 (en) 2008-10-27 2012-10-02 Polymedix, Inc. Synthetic mimetics of host defense and uses thereof
BRPI0922947A2 (pt) * 2008-12-10 2015-08-25 Polymedix Inc Métodos para inibir o crescimento de uma espécie de mycobacterium, e para tratar um animal tendo uma infecção de mycobacterium, e, composto.
KR101094299B1 (ko) 2009-12-17 2011-12-19 삼성모바일디스플레이주식회사 선형 증발원 및 이를 포함하는 증착 장치
RU2606128C2 (ru) 2011-05-16 2017-01-10 Селлсьютикс Корпорейшн Соединения для применения в лечении мукозита
US9469616B2 (en) 2011-12-13 2016-10-18 Cellceutix Corporation Cyclic compounds and methods of making and using the same
AU2013209622A1 (en) * 2012-01-18 2014-09-11 Cellceutix Corporation Compounds and methods for treating Candidiasis and Aspergillus infections
CN109305926B (zh) * 2018-10-18 2021-06-25 吉林大学 一种可形成分子内氢键的芳酰胺类金属配体及其制备方法与应用
US11771694B2 (en) 2020-06-05 2023-10-03 Innovation Pharmaceuticals Inc. Arylamide compounds for treatment and prevention of viral infections

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Also Published As

Publication number Publication date
EP1855704A2 (en) 2007-11-21
EP2298074A2 (en) 2011-03-23
TW201231063A (en) 2012-08-01
EP2433627A1 (en) 2012-03-28
KR20080004475A (ko) 2008-01-09
JP2008531585A (ja) 2008-08-14
AU2006218805A1 (en) 2006-09-08
EP1855704A4 (en) 2009-12-02
EP2433628A1 (en) 2012-03-28
TW200722098A (en) 2007-06-16
EP2298074A3 (en) 2011-10-26
WO2006093813A2 (en) 2006-09-08
EP2301349A2 (en) 2011-03-30
WO2006093813A3 (en) 2007-11-22
US20060241052A1 (en) 2006-10-26

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140116